Bus from Buenos Aires to Santa Cruz de la Sierra from $132

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Compare all timetables for the bus from Buenos Aires to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from Buenos Aires to Santa Cruz de la Sierra from various bus operators like Autobuses Quirquincho, La Preferida Bus or Bolpar for the next days.
today
from $241
tomorrow
from $132
Tuesday
Wednesday
from $241
Thursday
from $151
Friday
from $241
Saturday
from $151

Cheapest bus trips today

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $241
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $135? You can find the corresponding connections below.
    • Plataforma 10
      49h 0m
      0
      3:00 PM
      Buenos Aires
      Retiro Bus Station
      9:45 AM
      Asunción, PY
      Bus Station
      0
      Plataforma 10
      Premium Economy
      $50
      • Waiting Time 10h 15m
    • Plataforma 10
      20h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Basic
      $56
    Travel time is 11h 0m longer, but you will save $135

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Autobuses Quirquincho
    37h 55m
    0
    3:00 PM
    Buenos Aires
    Retiro Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $132
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $132
  • Bolpar
    39h 0m
    0
    3:00 PM
    Buenos Aires
    Retiro Bus Station
    6:00 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Bolpar
    First Class
    $132
  • Bolpar
    37h 0m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    6:00 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Bolpar
    First Class
    $132
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $241
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $26? You can find the corresponding connections below.
    • Plataforma 10
      49h 0m
      0
      3:00 PM
      Buenos Aires
      Retiro Bus Station
      9:45 AM
      Asunción, PY
      Bus Station
      0
      Plataforma 10
      Premium Economy
      $50
      • Waiting Time 10h 15m
    • Plataforma 10
      20h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Basic
      $56
    Travel time is 13h 5m longer, but you will save $26

Cheapest bus trips Wednesday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $241
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $135? You can find the corresponding connections below.
    • Plataforma 10
      49h 0m
      0
      3:00 PM
      Buenos Aires
      Retiro Bus Station
      9:45 AM
      Asunción, PY
      Bus Station
      0
      Plataforma 10
      Premium Economy
      $50
      • Waiting Time 10h 15m
    • Plataforma 10
      20h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Basic
      $56
    Travel time is 11h 0m longer, but you will save $135

Cheapest bus trips Thursday

Prices are for one way and one person
  • Autobuses Quirquincho
    37h 55m
    0
    3:00 PM
    Buenos Aires
    Retiro Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $151
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $151
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $160
  • Autobuses Quirquincho
    37h 55m
    0
    3:00 PM
    Buenos Aires
    Retiro Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $170
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $45? You can find the corresponding connections below.
    • Plataforma 10
      49h 0m
      0
      3:00 PM
      Buenos Aires
      Retiro Bus Station
      9:45 AM
      Asunción, PY
      Bus Station
      0
      Plataforma 10
      Premium Economy
      $50
      • Waiting Time 10h 15m
    • Plataforma 10
      20h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Basic
      $56
    Travel time is 13h 5m longer, but you will save $45

Cheapest bus trips Friday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $241
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $135? You can find the corresponding connections below.
    • Plataforma 10
      49h 0m
      0
      3:00 PM
      Buenos Aires
      Retiro Bus Station
      9:45 AM
      Asunción, PY
      Bus Station
      0
      Plataforma 10
      Premium Economy
      $50
      • Waiting Time 10h 15m
    • Plataforma 10
      20h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Basic
      $56
    Travel time is 11h 0m longer, but you will save $135

Cheapest bus trips Saturday

Prices are for one way and one person
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $151
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $241
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $45? You can find the corresponding connections below.
    • Plataforma 10
      49h 0m
      0
      3:00 PM
      Buenos Aires
      Retiro Bus Station
      9:45 AM
      Asunción, PY
      Bus Station
      0
      Plataforma 10
      Premium Economy
      $50
      • Waiting Time 10h 15m
    • Plataforma 10
      20h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Basic
      $56
    Travel time is 13h 5m longer, but you will save $45

Facts about the bus from Buenos Aires to Santa Cruz de la Sierra

Compare all providers like Autobuses Quirquincho, La Preferida Bus and Bolpar that travel 3 times every day by bus from Buenos Aires to Santa Cruz de la Sierra in one click! Book your bus ticket from Buenos Aires to Santa Cruz de la Sierra starting from $132!

Cheapest Bus $132
Fastest Bus 35h 55m
Earliest Bus 4:30 PM
Latest Bus 5:00 PM
Daily Bus Routes 3 Ø
Distance 1,199.3 miles
Bus Companies Autobuses Quirquincho, La Preferida Bus and Bolpar

Cheapest bus connections from Buenos Aires to Santa Cruz de la Sierra

Every day, 3 buses from 3 bus companies leave Buenos Aires for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/30/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/30
$241
Monday 03/31
$132
Tuesday 04/01
Wednesday 04/02
$241
Thursday 04/03
$151
Friday 04/04
$241
Saturday 04/05
$151
Sunday 04/06
$182
Monday 04/07
$151
Tuesday 04/08
$182
Wednesday 04/09
$151
Thursday 04/10
Friday 04/11
$182
Saturday 04/12
Sunday 04/13
$182
Monday 04/14
Tuesday 04/15
Wednesday 04/16
Thursday 04/17
Friday 04/18
Saturday 04/19
Sunday 04/20
Monday 04/21
$241
Tuesday 04/22
$151
Wednesday 04/23
Thursday 04/24
Friday 04/25
$151
Saturday 04/26

How to save money travelling from Buenos Aires to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buenos Aires to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buenos Aires to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buenos Aires to Santa Cruz de la Sierra are also emptier.

Beloved bus companies from Buenos Aires to Santa Cruz de la Sierra

These are the most booked bus companies between Buenos Aires to Santa Cruz de la Sierra from our users.

La Preferida Bus from Buenos Aires to Santa Cruz de la Sierra

La Preferida Bus

Here you will find the key facts about the La Preferida Bus bus route Buenos Aires to Santa Cruz de la Sierra:

Cheapest Price $241
Fastest Bus 38h 0m
Earliest Bus 4:30 PM
Last Bus 4:30 PM
Daily Connections 1 Ø
Found on 3/27/2025

All bus stations and stops in Buenos Aires and Santa Cruz de la Sierra

In the map below, you can see where to find all bus stations in Buenos Aires and Santa Cruz de la Sierra.

Service and Comfort on the bus from Buenos Aires to Santa Cruz de la Sierra

Want to know which seat classes are available on the buses from Buenos Aires to Santa Cruz de la Sierra? Or which bus companies serve the route Buenos Aires to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the Buenos Aires to Santa Cruz de la Sierra bus

How much does a Buenos Aires Santa Cruz de la Sierra bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $132 and takes 37h 55m to reach Santa Cruz de la Sierra. Compare offers to save money!

How much could I save by comparing buses from Buenos Aires to Santa Cruz de la Sierra?

This route is offered by 3 companies with a range of ticket prices between $132 and $241. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Cruz de la Sierra.

On average, how many connections are available from Buenos Aires to Santa Cruz de la Sierra each day?

Every day, the Buenos Aires to Santa Cruz de la Sierra bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buenos Aires to Santa Cruz de la Sierra take?

The fastest bus from Buenos Aires to Santa Cruz de la Sierra is offered by Autobuses Quirquincho and takes 35h 55m. Bus tickets for this connection cost $159. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buenos Aires to Santa Cruz de la Sierra?

The earliest bus arriving in Santa Cruz de la Sierra from Buenos Aires starts at 4:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buenos Aires to Santa Cruz de la Sierra?

The latest bus trip departing from Buenos Aires for Santa Cruz de la Sierra starts at 5:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buenos Aires Santa Cruz de la Sierra route?

When traveling by bus from Buenos Aires to Santa Cruz de la Sierra, passengers can travel with Autobuses Quirquincho, La Preferida Bus and Bolpar. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buenos Aires and Santa Cruz de la Sierra?

You can check all the direct connections between Buenos Aires and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Autobuses Quirquincho, La Preferida Bus and Bolpar.

What can I take with me on the Buenos Aires to Santa Cruz de la Sierra bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buenos Aires Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buenos Aires Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buenos Aires to Santa Cruz de la Sierra on your planned travel date.

Available seat classes which are offered on the bus route Buenos Aires to Santa Cruz de la Sierra

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Buenos Aires and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to Buenos Aires and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Buenos Aires and to Santa Cruz de la Sierra
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