Bus from Florence, SC to Durham, NC from $47

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Compare all timetables for the bus from Florence, SC to Durham, NC

Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Durham, NC from various bus operators like Wanda Coach or FlixBus for the next days.
today
from $60
tomorrow
Thursday
from $55
Friday
from $60
Saturday
from $47
Sunday
from $47
Monday
from $60

Cheapest bus trips today

Prices are for one way and one person
  • Wanda Coach
    3h 30m
    0
    7:00 PM
    Florence, SC
    Exxon Gas Station
    10:30 PM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 30m
    0
    9:00 PM
    Florence, SC
    Exxon Gas Station
    12:30 AM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      4h 51m
      0
      11:59 PM
      Florence, SC
      TA Travel Center
      2:35 AM
      Raleigh, NC
      New Bern Ave
      0
      FlixBus
      Economy
      $34
      • Waiting Time 1h 40m
    • Busbud
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Transportation Center
      0
      Busbud
      Economy
      $10
    Travel time is 1h 21m longer, but you will save $16

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    8h 26m
    0
    11:59 PM
    Florence, SC
    TA Travel Center
    8:25 AM
    Durham, NC
    Exxon
    0
    FlixBus
    Economy
    $55
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      4h 51m
      0
      11:59 PM
      Florence, SC
      TA Travel Center
      2:35 AM
      Raleigh, NC
      New Bern Ave
      0
      FlixBus
      Economy
      $34
      • Waiting Time 1h 40m
    • Busbud
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Transportation Center
      0
      Busbud
      Economy
      $10
    Travel Time is 3h 35m shorter, and you will save $11

Cheapest bus trips Friday

Prices are for one way and one person
  • Wanda Coach
    3h 30m
    0
    7:00 PM
    Florence, SC
    Exxon Gas Station
    10:30 PM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 30m
    0
    9:00 PM
    Florence, SC
    Exxon Gas Station
    12:30 AM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      4h 51m
      0
      11:59 PM
      Florence, SC
      TA Travel Center
      2:35 AM
      Raleigh, NC
      New Bern Ave
      0
      FlixBus
      Economy
      $34
      • Waiting Time 1h 40m
    • Busbud
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Transportation Center
      0
      Busbud
      Economy
      $10
    Travel time is 1h 21m longer, but you will save $16

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    8h 26m
    0
    11:59 PM
    Florence, SC
    TA Travel Center
    8:25 AM
    Durham, NC
    Exxon
    0
    FlixBus
    Economy
    $47
  • Wanda Coach
    3h 30m
    0
    7:00 PM
    Florence, SC
    Exxon Gas Station
    10:30 PM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 30m
    0
    9:00 PM
    Florence, SC
    Exxon Gas Station
    12:30 AM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 30m
    0
    7:00 PM
    Florence, SC
    Shell Gas Station
    10:30 PM
    Durham, NC
    BP Hillandale Rd
    0
    Wanda Coach
    Economy
    $60

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    8h 26m
    0
    11:59 PM
    Florence, SC
    TA Travel Center
    8:25 AM
    Durham, NC
    Exxon
    0
    FlixBus
    Economy
    $47
  • Wanda Coach
    3h 30m
    0
    7:00 PM
    Florence, SC
    Shell Gas Station
    10:30 PM
    Durham, NC
    BP Hillandale Rd
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 30m
    0
    9:00 PM
    Florence, SC
    Shell Gas Station
    12:30 AM
    Durham, NC
    BP Hillandale Rd
    0
    Wanda Coach
    Economy
    $60

Cheapest bus trips Monday

Prices are for one way and one person
  • Wanda Coach
    3h 30m
    0
    7:00 PM
    Florence, SC
    Exxon Gas Station
    10:30 PM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 30m
    0
    9:00 PM
    Florence, SC
    Exxon Gas Station
    12:30 AM
    Durham, NC
    BP Guess Road
    0
    Wanda Coach
    Economy
    $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      4h 51m
      0
      11:59 PM
      Florence, SC
      TA Travel Center
      2:35 AM
      Raleigh, NC
      New Bern Ave
      0
      FlixBus
      Economy
      $34
      • Waiting Time 1h 40m
    • Busbud
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Transportation Center
      0
      Busbud
      Economy
      $10
    Travel time is 1h 21m longer, but you will save $16

Facts about the bus from Florence, SC to Durham, NC

Compare all providers like Wanda Coach and FlixBus that travel 2 times every day by bus from Florence, SC to Durham, NC in one click! Book your bus ticket from Florence, SC to Durham, NC starting from $47!

Cheapest Bus $47
Fastest Bus 3h 30m
Earliest Bus 7:00 PM
Latest Bus 9:00 PM
Daily Bus Routes 2 Ø
Distance 133.6 miles
Bus Companies Wanda Coach and FlixBus

Cheapest bus connections from Florence, SC to Durham, NC

Every day, 2 buses from 2 bus companies leave Florence, SC for Durham, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/23/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/20
Monday 04/21
Tuesday 04/22
$60
Wednesday 04/23
Thursday 04/24
$55
Friday 04/25
$60
Saturday 04/26
$60
Sunday 04/27
$60
Monday 04/28
$60
Tuesday 04/29
$60
Wednesday 04/30
Thursday 05/01
$46
Friday 05/02
Saturday 05/03
Sunday 05/04
Monday 05/05
Tuesday 05/06
Wednesday 05/07
Thursday 05/08
Friday 05/09
Saturday 05/10
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
Friday 05/16
Saturday 05/17

How to save money travelling from Florence, SC to Durham, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence, SC to Durham, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Durham, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Durham, NC are also emptier.

Beloved bus companies from Florence, SC to Durham, NC

These are the most booked bus companies between Florence, SC to Durham, NC from our users.

FlixBus from Florence, SC to Durham, NC

FlixBus

Here you will find the key facts about the FlixBus bus route Florence, SC to Durham, NC:

Cheapest Price $47
Fastest Bus 8h 26m
Earliest Bus 11:59 PM
Last Bus 11:59 PM
Daily Connections 1 Ø
Found on 4/19/2025

All bus stations and stops in Florence, SC and Durham, NC

In the map below, you can see where to find all bus stations in Florence, SC and Durham, NC.

Service and Comfort on the bus from Florence, SC to Durham, NC

Want to know which seat classes are available on the buses from Florence, SC to Durham, NC? Or which bus companies serve the route Florence, SC to Durham, NC? Below you will find answers to your questions.

FAQs about the Florence, SC to Durham, NC bus

How much does a Florence, SC Durham, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $47 and takes 8h 26m to reach Durham, NC. Compare offers to save money!

How much could I save by comparing buses from Florence, SC to Durham, NC?

This route is offered by 2 companies with a range of ticket prices between $47 and $60. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Durham, NC.

On average, how many connections are available from Florence, SC to Durham, NC each day?

Every day, the Florence, SC to Durham, NC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence, SC to Durham, NC take?

The fastest bus from Florence, SC to Durham, NC is offered by Wanda Coach and takes 3h 30m. Bus tickets for this connection cost $60. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence, SC to Durham, NC?

The earliest bus arriving in Durham, NC from Florence, SC starts at 7:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence, SC to Durham, NC?

The latest bus trip departing from Florence, SC for Durham, NC starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence, SC Durham, NC route?

When traveling by bus from Florence, SC to Durham, NC, passengers can travel with Wanda Coach and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence, SC and Durham, NC?

You can check all the direct connections between Florence, SC and Durham, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Wanda Coach and FlixBus.

What can I take with me on the Florence, SC to Durham, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Durham, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence, SC Durham, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Durham, NC on your planned travel date.

Available seat classes which are offered on the bus route Florence, SC to Durham, NC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence, SC and to Durham, NC

Here’s an overview of the most popular bus routes to Florence, SC and to Durham, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Florence, SC and to Durham, NC
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