Bus from Guanajuato to Mexico City from $46

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Compare all timetables for the bus from Guanajuato to Mexico City

Here is a selection of the cheapest bus trips from the schedule from Guanajuato to Mexico City from various bus operators like ETN Autobuses or Primera Plus for the next days.
today
from $46
tomorrow
from $46
Friday
from $46
Saturday
from $46
Sunday
from $46
Monday
from $46
Tuesday
from $46

Cheapest bus trips today

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    7:45 AM
    Guanajuato
    Central Bus Station
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $62
  • ETN Autobuses
    6h 15m
    0
    7:45 AM
    Guanajuato
    Central Bus Station
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Economy
    $62
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    7:45 AM
    Guanajuato
    Central Bus Station
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $63
  • ETN Autobuses
    6h 10m
    0
    10:30 AM
    Guanajuato
    Central Bus Station
    4:40 PM
    Mexico City
    Norte Bus Station
    0
    ETN Autobuses
    Premium Economy
    $66
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips Friday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $62
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Economy
    $62
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips Saturday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Economy
    $62
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $63
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips Sunday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Economy
    $62
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $62
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips Monday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Economy
    $63
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $63
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    12:45 AM
    Guanajuato
    Central Bus Station
    5:30 AM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    8:00 AM
    Guanajuato
    Central Bus Station
    12:45 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • Primera Plus
    4h 45m
    0
    9:50 AM
    Guanajuato
    Central Bus Station
    2:35 PM
    Mexico City
    Norte Bus Station
    0
    Primera Plus
    Economy
    $46
  • ETN Autobuses
    6h 15m
    0
    5:45 AM
    Guanajuato
    Central Bus Station
    12:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Economy
    $62
  • ETN Autobuses
    6h 15m
    0
    7:45 AM
    Guanajuato
    Central Bus Station
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $62
  • Did you know that if you travel from Guanajuato to Mexico City via Irapuato, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      6h 15m
      0
      5:30 PM
      Guanajuato
      Central Bus Station
      6:30 PM
      Irapuato
      Central Bus Station
      0
      Primera Plus
      Economy
      $6
      • Waiting Time 0h 15m
    • Busbud
      5h 0m
      0
      6:45 PM
      Irapuato
      Hospital Militar Regional Bus Stop
      11:45 PM
      Mexico City
      Norte Bus Station
      0
      Busbud
      Premium Economy
      $19
    Travel time is 1h 30m longer, but you will save $21

Frequency of bus connections between Guanajuato and Mexico City

See here how frequent the connections between Guanajuato and Mexico City are, during different times and days of the week.
Tuesday is the busiest day, with more than 21 daily buses from Guanajuato to Mexico City. Sunday has instead the fewest connections, with only 19 daily coaches between Guanajuato and Mexico City.
The busiest time of the day is the Morning, with 52 buses from Guanajuato to Mexico City, while Night sees the fewest connections between Guanajuato and Mexico City, with 16 offers.

Facts about the bus from Guanajuato to Mexico City

Compare all providers like ETN Autobuses and Primera Plus that travel 19 times every day by bus from Guanajuato to Mexico City in one click! Book your bus ticket from Guanajuato to Mexico City starting from $46!

Cheapest Bus $46
Fastest Bus 4h 45m
Earliest Bus 12:45 AM
Latest Bus 11:59 PM
Daily Bus Routes 19 Ø
Distance 176.1 miles
Bus Companies ETN Autobuses and Primera Plus

Cheapest bus connections from Guanajuato to Mexico City

Every day, 19 buses from 2 bus companies leave Guanajuato for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/26/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/23
Monday 03/24
Tuesday 03/25
Wednesday 03/26
$46
Thursday 03/27
$63
Friday 03/28
$46
Saturday 03/29
$46
Sunday 03/30
$62
Monday 03/31
$46
Tuesday 04/01
$46
Wednesday 04/02
$62
Thursday 04/03
$63
Friday 04/04
$63
Saturday 04/05
$44
Sunday 04/06
$46
Monday 04/07
$61
Tuesday 04/08
$46
Wednesday 04/09
$66
Thursday 04/10
Friday 04/11
$46
Saturday 04/12
$62
Sunday 04/13
$46
Monday 04/14
$66
Tuesday 04/15
$46
Wednesday 04/16
$67
Thursday 04/17
$67
Friday 04/18
$46
Saturday 04/19

The cheapest time to travel from Guanajuato to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from Guanajuato to Mexico City, for the next 30 days.
With a price starting from $46, Sunday is the cheapest day for a bus from Guanajuato to Mexico City. Sunday instead is the most expensive day with prices starting from $46.
Morning is the cheapest day time for bus tickets from Guanajuato to Mexico City, with $46. Morning is the most expensive time of the day with prices starting from $46.

How to save money travelling from Guanajuato to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Guanajuato to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Guanajuato to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Guanajuato to Mexico City are also emptier.

Beloved bus companies from Guanajuato to Mexico City

These are the most booked bus companies between Guanajuato to Mexico City from our users.

Primera Plus from Guanajuato to Mexico City

Primera Plus

Here you will find the key facts about the Primera Plus bus route Guanajuato to Mexico City:

Cheapest Price $46
Fastest Bus 4h 45m
Earliest Bus 12:45 AM
Last Bus 6:00 PM
Daily Connections 8 Ø
Found on 3/25/2025

ETN Autobuses from Guanajuato to Mexico City

ETN Autobuses

Here you will find the key facts about the ETN Autobuses bus route Guanajuato to Mexico City:

Cheapest Price $62
Fastest Bus 5h 16m
Earliest Bus 7:45 AM
Last Bus 11:59 PM
Daily Connections 11 Ø
Found on 3/25/2025

All bus stations and stops in Guanajuato and Mexico City

In the map below, you can see where to find all bus stations in Guanajuato and Mexico City.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Guanajuato to Mexico City? Compare all modes of transports from Guanajuato to Mexico City.

Service and Comfort on the bus from Guanajuato to Mexico City

Want to know which seat classes are available on the buses from Guanajuato to Mexico City? Or which bus companies serve the route Guanajuato to Mexico City? Below you will find answers to your questions.

FAQs about the Guanajuato to Mexico City bus

How much does a Guanajuato Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $46 and takes 4h 45m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from Guanajuato to Mexico City?

This route is offered by 2 companies with a range of ticket prices between $46 and $71. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from Guanajuato to Mexico City each day?

Every day, the Guanajuato to Mexico City bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Guanajuato to Mexico City take?

The fastest bus from Guanajuato to Mexico City is offered by Primera Plus and takes 4h 45m. Bus tickets for this connection cost $46. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Guanajuato to Mexico City?

The earliest bus arriving in Mexico City from Guanajuato starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Guanajuato to Mexico City?

The latest bus trip departing from Guanajuato for Mexico City starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Guanajuato Mexico City route?

When traveling by bus from Guanajuato to Mexico City, passengers can travel with ETN Autobuses and Primera Plus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Guanajuato and Mexico City?

You can check all the direct connections between Guanajuato and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses and Primera Plus.

What can I take with me on the Guanajuato to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Guanajuato Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Guanajuato Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Guanajuato to Mexico City on your planned travel date.

Available seat classes which are offered on the bus route Guanajuato to Mexico City

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Guanajuato and to Mexico City

Here’s an overview of the most popular bus routes to Guanajuato and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from San Miguel de Allende to Guanajuato Bus from San Miguel de Allende to Guanajuato
Bus from Guadalajara, JC to Guanajuato Bus from Guadalajara, JC to Guanajuato
Bus from Santiago de Queretaro to Guanajuato Bus from Santiago de Queretaro to Guanajuato
Buses León de los Aldama - Guanajuato Buses León de los Aldama - Guanajuato
Bus from Ciudad Juárez to Mexico City Bus from Ciudad Juárez to Mexico City
Buses to Mexico City from Monterrey, NL Buses to Mexico City from Monterrey, NL
Bus to Mexico City from Veracruz Bus to Mexico City from Veracruz
Buses to Mexico City from Mazatlán Buses to Mexico City from Mazatlán
Popular Airport Shuttles to Guanajuato and to Mexico City
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