Bus from Lafayette, LA to Chicago from $128

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Lafayette, LA to Chicago

Here is a selection of the cheapest bus trips from the schedule from Lafayette, LA to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today
tomorrow
$217
Monday
$140
Tuesday
$186
Wednesday
$190
Thursday
$136
Friday
$179

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 15m 8:50 PM Lafayette, LA TA Travel Center 10:05 PM Chicago Downtown Bus Station  Economy $217
FlixBus 33h 0m 11:10 AM Lafayette, LA TA Travel Center 8:10 PM Chicago Downtown Bus Station  Economy $223
Greyhound US 28h 30m 5:35 PM Lafayette, LA Bus Stop 10:05 PM Chicago Downtown Bus Station  Economy $225
Greyhound US 33h 25m 10:35 PM Lafayette, LA Bus Stop 8:00 AM Chicago Union Station  Economy $226
Greyhound US 33h 50m 10:35 PM Lafayette, LA Bus Stop 8:25 AM Chicago Downtown Bus Station  Economy $226

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 28h 15m 5:35 PM Lafayette, LA Bus Stop 9:50 PM Chicago 95th Red Line Station  Economy $140
FlixBus 34h 55m 2:30 AM Lafayette, LA TA Travel Center 1:25 PM Chicago 95th Red Line Station  Economy $140
Greyhound US 30h 20m 9:35 AM Lafayette, LA Bus Stop 3:55 PM Chicago 95th Red Line Station  Economy $141
Greyhound US 32h 0m 9:20 PM Lafayette, LA Bus Stop 5:20 AM Chicago 95th Red Line Station  Economy $141
FlixBus 25h 0m 8:50 PM Lafayette, LA TA Travel Center 9:50 PM Chicago 95th Red Line Station  Economy $141

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 33h 25m 10:35 PM Lafayette, LA Bus Stop 8:00 AM Chicago Union Station  Economy $186
Greyhound US 33h 50m 10:35 PM Lafayette, LA Bus Stop 8:25 AM Chicago Downtown Bus Station  Economy $186
Greyhound US 30h 50m 9:20 PM Lafayette, LA Bus Stop 4:10 AM Chicago Downtown Bus Station  Economy $187
FlixBus 35h 40m 2:30 AM Lafayette, LA TA Travel Center 2:10 PM Chicago Union Station  Economy $191
FlixBus 35h 20m 12:50 PM Lafayette, LA TA Travel Center 12:10 AM Chicago Downtown Bus Station  Economy $204
  • Did you know that if you travel from Lafayette, LA to Chicago via Baton Rouge, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      30h 45m
      0
      10:35 PM
      Lafayette, LA
      Bus Stop
      11:40 PM
      Baton Rouge
      Park & Ride
      0
      FlixBus
      Economy
      $18
      • Waiting Time 6h 25m
    • FlixBus
      23h 15m
      0
      6:05 AM
      Baton Rouge
      Park & Ride
      5:20 AM
      Chicago
      95th Red Line Station
      0
      FlixBus
      Economy
      $139
    Travel Time is 0h 5m shorter, and you will save $29

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 30h 35m 5:35 PM Lafayette, LA Bus Stop 12:10 AM Chicago Downtown Bus Station  Economy $190
FlixBus 35h 20m 12:50 PM Lafayette, LA TA Travel Center 12:10 AM Chicago Downtown Bus Station  Economy $190
Greyhound US 30h 0m 2:00 AM Lafayette, LA Bus Stop 8:00 AM Chicago Union Station  Economy $191
Greyhound US 30h 25m 2:00 AM Lafayette, LA Bus Stop 8:25 AM Chicago Downtown Bus Station  Economy $191
FlixBus 37h 40m 6:20 PM Lafayette, LA TA Travel Center 8:00 AM Chicago Union Station  Economy $219
  • Did you know that if you travel from Lafayette, LA to Chicago via Baton Rouge, you can save more than $33? You can find the corresponding connections below.
    • FlixBus
      30h 45m
      0
      10:35 PM
      Lafayette, LA
      Bus Stop
      11:40 PM
      Baton Rouge
      Park & Ride
      0
      FlixBus
      Economy
      $18
      • Waiting Time 6h 25m
    • FlixBus
      23h 15m
      0
      6:05 AM
      Baton Rouge
      Park & Ride
      5:20 AM
      Chicago
      95th Red Line Station
      0
      FlixBus
      Economy
      $139
    Travel time is 0h 45m longer, but you will save $33

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 33h 0m 2:30 AM Lafayette, LA TA Travel Center 11:30 AM Chicago Downtown Bus Station  Economy $136
Greyhound US 30h 50m 9:20 PM Lafayette, LA Bus Stop 4:10 AM Chicago Downtown Bus Station  Economy $138
Greyhound US 28h 30m 5:35 PM Lafayette, LA Bus Stop 10:05 PM Chicago Downtown Bus Station  Economy $139
FlixBus 25h 15m 8:50 PM Lafayette, LA TA Travel Center 10:05 PM Chicago Downtown Bus Station  Economy $140
Greyhound US 30h 0m 2:00 AM Lafayette, LA Bus Stop 8:00 AM Chicago Canal & Van Buren  Economy $147

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 15m 8:50 PM Lafayette, LA TA Travel Center 10:05 PM Chicago Downtown Bus Station  Economy $179
Greyhound US 28h 30m 5:35 PM Lafayette, LA Bus Stop 10:05 PM Chicago Downtown Bus Station  Economy $186
FlixBus 32h 50m 11:20 AM Lafayette, LA TA Travel Center 8:10 PM Chicago Downtown Bus Station  Economy $191
FlixBus 33h 0m 2:30 AM Lafayette, LA TA Travel Center 11:30 AM Chicago Downtown Bus Station  Economy $196
Greyhound US 29h 40m 9:35 AM Lafayette, LA Bus Stop 3:15 PM Chicago Downtown Bus Station  Economy $204
  • Did you know that if you travel from Lafayette, LA to Chicago via Baton Rouge, you can save more than $22? You can find the corresponding connections below.
    • FlixBus
      30h 45m
      0
      10:35 PM
      Lafayette, LA
      Bus Stop
      11:40 PM
      Baton Rouge
      Park & Ride
      0
      FlixBus
      Economy
      $18
      • Waiting Time 6h 25m
    • FlixBus
      23h 15m
      0
      6:05 AM
      Baton Rouge
      Park & Ride
      5:20 AM
      Chicago
      95th Red Line Station
      0
      FlixBus
      Economy
      $139
    Travel time is 5h 30m longer, but you will save $22

Best Price Offer: The price for the cheapest bus from Lafayette, LA to Chicago is $128 on 1/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Lafayette, LA and Chicago

See here how frequent the connections between Lafayette, LA and Chicago are, during different times and days of the week.
Monday is the busiest day, with more than 36 daily buses from Lafayette, LA to Chicago. Wednesday has instead the fewest connections, with only 9 daily coaches between Lafayette, LA and Chicago.
The busiest time of the day is the Evening, with 41 buses from Lafayette, LA to Chicago, while Morning sees the fewest connections between Lafayette, LA and Chicago, with 16 offers.

Facts about the bus from Lafayette, LA to Chicago

Compare all providers like Greyhound US and FlixBus that travel 18 times every day by bus from Lafayette, LA to Chicago in one click! Book your bus ticket from Lafayette, LA to Chicago starting from $128!

Cheapest Bus $128
Fastest Bus 25h 0m
Earliest Bus 2:00 AM
Latest Bus 10:35 PM
Daily Bus Routes 18 Ø
Distance 841.4 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Lafayette, LA to Chicago

Every day, 18 buses from 2 bus companies leave Lafayette, LA for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/20/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
$243
Monday 12/22
$140
Tuesday 12/23
$227
Wednesday 12/24
$190
Thursday 12/25
$136
Friday 12/26
$179
Saturday 12/27
Sunday 12/28
$190
Monday 12/29
$174
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
Monday 01/05
Tuesday 01/06
Wednesday 01/07
$151
Thursday 01/08
$128
Friday 01/09
Saturday 01/10

The cheapest time to travel from Lafayette, LA to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Lafayette, LA to Chicago, for the next 30 days.
With a price starting from $128, Thursday is the cheapest day for a bus from Lafayette, LA to Chicago. Tuesday instead is the most expensive day with prices starting from $186.
Night is the cheapest day time for bus tickets from Lafayette, LA to Chicago, with $128. Morning is the most expensive time of the day with prices starting from $141.

How to save money travelling from Lafayette, LA to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lafayette, LA to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lafayette, LA to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lafayette, LA to Chicago are also emptier.

Beloved bus companies from Lafayette, LA to Chicago

These are the most booked bus companies between Lafayette, LA to Chicago from our users.

FlixBus from Lafayette, LA to Chicago

FlixBus

Here you will find the key facts about the FlixBus bus route Lafayette, LA to Chicago:

Cheapest Price $136
Fastest Bus 25h 0m
Earliest Bus 2:30 AM
Last Bus 8:50 PM
Daily Connections 6 Ø
Found on 12/18/2025

All bus stations and stops in Lafayette, LA and Chicago

In the map below, you can see where to find all bus stations in Lafayette, LA and Chicago.

Service and Comfort on the bus from Lafayette, LA to Chicago

Want to know which seat classes are available on the buses from Lafayette, LA to Chicago? Or which bus companies serve the route Lafayette, LA to Chicago? Below you will find answers to your questions.

FAQs about the Lafayette, LA to Chicago bus

How much does a Lafayette, LA Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $128 and takes 33h 0m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Lafayette, LA to Chicago?

This route is offered by 2 companies with a range of ticket prices between $128 and $304. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Lafayette, LA to Chicago each day?

Every day, the Lafayette, LA to Chicago bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lafayette, LA to Chicago take?

The fastest bus from Lafayette, LA to Chicago is offered by FlixBus and takes 25h 0m. Bus tickets for this connection cost $157. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lafayette, LA to Chicago?

The earliest bus arriving in Chicago from Lafayette, LA starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lafayette, LA to Chicago?

The latest bus trip departing from Lafayette, LA for Chicago starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lafayette, LA Chicago route?

When traveling by bus from Lafayette, LA to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lafayette, LA and Chicago?

You can check all the direct connections between Lafayette, LA and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Lafayette, LA to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lafayette, LA Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lafayette, LA Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lafayette, LA to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Lafayette, LA to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 18 daily trips between Lafayette, LA and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lafayette, LA to Chicago?

Prices and availability for 18 trips between Lafayette, LA and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lafayette, LA to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lafayette, LA and to Chicago

Here’s an overview of the most popular bus routes to Lafayette, LA and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Lafayette, LA from Jackson, MS Buses to Lafayette, LA from Jackson, MS
Buses Montrose, CO to Lafayette, LA Buses Montrose, CO to Lafayette, LA
Houston to Lafayette, LA bus Houston to Lafayette, LA bus
Buses from New Orleans, LA to Lafayette, LA Buses from New Orleans, LA to Lafayette, LA
Buses from Dallas to Chicago Buses from Dallas to Chicago
Buses Iowa City, IA to Chicago Buses Iowa City, IA to Chicago
Bus Bloomington, IN to Chicago Bus Bloomington, IN to Chicago
Buses Cleveland - Chicago Buses Cleveland - Chicago
Popular Airport Shuttles to Lafayette, LA and to Chicago
CheckMyBus › Buses in USA › Bus to Lafayette, LA › Bus to Chicago

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.