Bus from Mexico City to Guanajuato from $49

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Compare all timetables for the bus from Mexico City to Guanajuato

Here is a selection of the cheapest bus trips from the schedule from Mexico City to Guanajuato from various bus operators like ETN Autobuses or Primera Plus for the next days.
today
from $49
tomorrow
from $49
Tuesday
from $49
Wednesday
from $49
Thursday
from $49
Friday
from $49
Saturday
from $49

Cheapest bus trips today

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $64
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $65

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $64
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $65

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $64
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $65

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $64
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $64

Cheapest bus trips Thursday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $64
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $65

Cheapest bus trips Friday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $63
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $63

Cheapest bus trips Saturday

Prices are for one way and one person
  • Primera Plus
    4h 45m
    0
    6:20 AM
    Mexico City
    Norte Bus Station
    11:05 AM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    8:10 AM
    Mexico City
    Norte Bus Station
    12:55 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Primera Plus
    4h 45m
    0
    10:00 AM
    Mexico City
    Norte Bus Station
    2:45 PM
    Guanajuato
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Premium Economy
    $63
  • ETN Autobuses
    6h 30m
    0
    2:00 PM
    Mexico City
    Observatorio Central Bus Station
    8:30 PM
    Guanajuato
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $64

Frequency of bus connections between Mexico City and Guanajuato

See here how frequent the connections between Mexico City and Guanajuato are, during different times and days of the week.
Sunday is the busiest day, with more than 22 daily buses from Mexico City to Guanajuato. Monday has instead the fewest connections, with only 21 daily coaches between Mexico City and Guanajuato.
The busiest time of the day is the Afternoon, with 70 buses from Mexico City to Guanajuato, while Evening sees the fewest connections between Mexico City and Guanajuato, with 30 offers.

Facts about the bus from Mexico City to Guanajuato

Compare all providers like ETN Autobuses and Primera Plus that travel 21 times every day by bus from Mexico City to Guanajuato in one click! Book your bus ticket from Mexico City to Guanajuato starting from $49!

Cheapest Bus $49
Fastest Bus 4h 45m
Earliest Bus 6:20 AM
Latest Bus 11:50 PM
Daily Bus Routes 21 Ø
Distance 176.1 miles
Bus Companies ETN Autobuses and Primera Plus

Cheapest bus connections from Mexico City to Guanajuato

Every day, 21 buses from 2 bus companies leave Mexico City for Guanajuato: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/27
$64
Monday 04/28
$49
Tuesday 04/29
$49
Wednesday 04/30
$49
Thursday 05/01
$49
Friday 05/02
$63
Saturday 05/03
$49
Sunday 05/04
$63
Monday 05/05
$49
Tuesday 05/06
$49
Wednesday 05/07
$49
Thursday 05/08
Friday 05/09
$49
Saturday 05/10
$49
Sunday 05/11
$49
Monday 05/12
$49
Tuesday 05/13
$66
Wednesday 05/14
$49
Thursday 05/15
$48
Friday 05/16
$49
Saturday 05/17
$49
Sunday 05/18
$65
Monday 05/19
$66
Tuesday 05/20
$63
Wednesday 05/21
$49
Thursday 05/22
$49
Friday 05/23
$68
Saturday 05/24

The cheapest time to travel from Mexico City to Guanajuato

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to Guanajuato, for the next 30 days.
With a price starting from $49, Sunday is the cheapest day for a bus from Mexico City to Guanajuato. Sunday instead is the most expensive day with prices starting from $49.
Morning is the cheapest day time for bus tickets from Mexico City to Guanajuato, with $49. Morning is the most expensive time of the day with prices starting from $49.

How to save money travelling from Mexico City to Guanajuato

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to Guanajuato in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to Guanajuato, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to Guanajuato are also emptier.

Beloved bus companies from Mexico City to Guanajuato

These are the most booked bus companies between Mexico City to Guanajuato from our users.

Primera Plus from Mexico City to Guanajuato

Primera Plus

Here you will find the key facts about the Primera Plus bus route Mexico City to Guanajuato:

Cheapest Price $49
Fastest Bus 4h 45m
Earliest Bus 6:20 AM
Last Bus 11:50 PM
Daily Connections 8 Ø
Found on 4/26/2025

ETN Autobuses from Mexico City to Guanajuato

ETN Autobuses

Here you will find the key facts about the ETN Autobuses bus route Mexico City to Guanajuato:

Cheapest Price $63
Fastest Bus 5h 20m
Earliest Bus 6:30 AM
Last Bus 6:30 PM
Daily Connections 13 Ø
Found on 4/27/2025

All bus stations and stops in Mexico City and Guanajuato

In the map below, you can see where to find all bus stations in Mexico City and Guanajuato.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to Guanajuato? Compare all modes of transports from Mexico City to Guanajuato.

Service and Comfort on the bus from Mexico City to Guanajuato

Want to know which seat classes are available on the buses from Mexico City to Guanajuato? Or which bus companies serve the route Mexico City to Guanajuato? Below you will find answers to your questions.

FAQs about the Mexico City to Guanajuato bus

How much does a Mexico City Guanajuato bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $49 and takes 4h 45m to reach Guanajuato. Compare offers to save money!

How much could I save by comparing buses from Mexico City to Guanajuato?

This route is offered by 2 companies with a range of ticket prices between $49 and $71. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Guanajuato.

On average, how many connections are available from Mexico City to Guanajuato each day?

Every day, the Mexico City to Guanajuato bus route is served by approximately 21 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to Guanajuato take?

The fastest bus from Mexico City to Guanajuato is offered by Primera Plus and takes 4h 45m. Bus tickets for this connection cost $49. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to Guanajuato?

The earliest bus arriving in Guanajuato from Mexico City starts at 6:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to Guanajuato?

The latest bus trip departing from Mexico City for Guanajuato starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City Guanajuato route?

When traveling by bus from Mexico City to Guanajuato, passengers can travel with ETN Autobuses and Primera Plus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and Guanajuato?

You can check all the direct connections between Mexico City and Guanajuato by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses and Primera Plus.

What can I take with me on the Mexico City to Guanajuato bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City Guanajuato bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City Guanajuato bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to Guanajuato on your planned travel date.

Available seat classes which are offered on the bus route Mexico City to Guanajuato

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mexico City and to Guanajuato

Here’s an overview of the most popular bus routes to Mexico City and to Guanajuato. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Buses Mazatlán - Mexico City Buses Mazatlán - Mexico City
Buses from San Miguel de Allende to Guanajuato Buses from San Miguel de Allende to Guanajuato
Buses Guadalajara, JC - Guanajuato Buses Guadalajara, JC - Guanajuato
From Santiago de Queretaro to Guanajuato bus From Santiago de Queretaro to Guanajuato bus
Bus León de los Aldama to Guanajuato Bus León de los Aldama to Guanajuato
Popular Airport Shuttles to Mexico City and to Guanajuato
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