Bus Middlesbrough to Southampton - Compare all Companies

Compare all timetables for the bus from Middlesbrough to Southampton

Here is a selection of the cheapest bus trips from the schedule from Middlesbrough to Southampton from various bus operators like National Express for the next days.

today

$53

tomorrow

Sunday

$53

Monday

$56

Tuesday

$44

Wednesday

$57

Thursday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	National Express	10h 40m	1:25 PM	Middlesbrough	Bus Station	12:05 AM	Southampton	Bus Station		Economy	$53	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/19/2025 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/20/2025 12:05:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 10h 40m
	National Express	9h 20m	4:10 PM	Middlesbrough	Bus Station	1:30 AM	Southampton	Bus Station		Economy	$53	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/19/2025 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/20/2025 1:30:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 9h 20m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
National Express	9h 15m	4:15 PM	Middlesbrough	Bus Station	1:30 AM	Southampton	Bus Station	Economy	$53	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/21/2025 4:15:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/22/2025 1:30:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 9h 15m
National Express	10h 20m	9:30 AM	Middlesbrough	Bus Station	7:50 PM	Southampton	Bus Station	Economy	$57	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/21/2025 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/21/2025 7:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 20m
National Express	10h 35m	12:45 AM	Middlesbrough	Bus Station	11:20 AM	Southampton	Bus Station	Economy	$58	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/21/2025 12:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/21/2025 11:20:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 35m
National Express	10h 40m	1:25 PM	Middlesbrough	Bus Station	12:05 AM	Southampton	Bus Station	Economy	$61	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/21/2025 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/22/2025 12:05:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 10h 40m
National Express	10h 0m	7:15 AM	Middlesbrough	Bus Station	5:15 PM	Southampton	Bus Station	Economy	$71	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/21/2025 7:15:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/21/2025 5:15:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 10h 0m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
National Express	11h 10m	9:30 AM	Middlesbrough	Bus Station	8:40 PM	Southampton	Bus Station	Economy	$56	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/22/2025 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/22/2025 8:40:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 11h 10m
National Express	9h 20m	4:10 PM	Middlesbrough	Bus Station	1:30 AM	Southampton	Bus Station	Economy	$56	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/22/2025 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/23/2025 1:30:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 9h 20m
National Express	11h 10m	8:30 AM	Middlesbrough	Bus Station	7:40 PM	Southampton	Bus Station	Economy	$63	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/22/2025 8:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/22/2025 7:40:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 11h 10m
National Express	10h 40m	1:25 PM	Middlesbrough	Bus Station	12:05 AM	Southampton	Bus Station	Economy	$63	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/22/2025 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/23/2025 12:05:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 10h 40m
National Express	10h 35m	12:45 AM	Middlesbrough	Bus Station	11:20 AM	Southampton	Bus Station	Economy	$67	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/22/2025 12:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/22/2025 11:20:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 10h 35m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
National Express	10h 10m	1:25 PM	Middlesbrough	Bus Station	11:35 PM	Southampton	Bus Station	Economy	$44	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/23/2025 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/23/2025 11:35:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 10h 10m
National Express	10h 50m	4:10 PM	Middlesbrough	Bus Station	3:00 AM	Southampton	Bus Station	Economy	$44	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/23/2025 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/24/2025 3:00:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 10h 50m
National Express	10h 35m	12:45 AM	Middlesbrough	Bus Station	11:20 AM	Southampton	Bus Station	Economy	$61	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/23/2025 12:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/23/2025 11:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 10h 35m
National Express	10h 40m	9:30 AM	Middlesbrough	Bus Station	8:10 PM	Southampton	Bus Station	Economy	$65	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/23/2025 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/23/2025 8:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 40m
National Express	10h 30m	7:00 AM	Middlesbrough	Bus Station	5:30 PM	Southampton	Bus Station	Economy	$67	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/23/2025 7:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/23/2025 5:30:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 10h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
National Express	10h 35m	12:45 AM	Middlesbrough	Bus Station	11:20 AM	Southampton	Bus Station	Economy	$57	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/24/2025 12:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/24/2025 11:20:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 35m
National Express	10h 40m	9:30 AM	Middlesbrough	Bus Station	8:10 PM	Southampton	Bus Station	Economy	$65	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/24/2025 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/24/2025 8:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 40m
National Express	10h 30m	7:00 AM	Middlesbrough	Bus Station	5:30 PM	Southampton	Bus Station	Economy	$67	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/24/2025 7:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/24/2025 5:30:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 10h 30m
National Express	9h 50m	11:00 AM	Middlesbrough	Bus Station	8:50 PM	Southampton	Bus Station	Economy	$71	A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/24/2025 11:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 12/24/2025 8:50:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 9h 50m

Did you know that if you travel from Middlesbrough to Southampton via Leeds, you can save more than $7? You can find the corresponding connections below.
- National Express
  
  11h 20m
  
  0
  
  11:00 AM
  
  Middlesbrough
  Bus Station
  
  12:30 PM
  
  Leeds
  Bus Station
  
  0
  
  Economy
  
  $16
  
  A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 12/24/2025 11:00:00 AM to Bus Station, Leeds (United Kingdom) arriving at 12/24/2025 12:30:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 1h 30m
- National Express
  
  8h 50m
  
  0
  
  1:30 PM
  
  Leeds
  Bus Station
  
  10:20 PM
  
  Southampton
  Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from National Express goes from Bus Station, Leeds (United Kingdom) at 12/24/2025 1:30:00 PM to Bus Station, Southampton (United Kingdom) arriving at 12/24/2025 10:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 50m
Travel time is 1h 30m longer, but you will save $7

Best Price Offer: The price for the cheapest bus from Middlesbrough to Southampton is $35 on 12/16/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Middlesbrough and Southampton

See here how frequent the connections between Middlesbrough and Southampton are, during different times and days of the week.

Monday is the busiest day, with more than 7 daily buses from Middlesbrough to Southampton. Friday has instead the fewest connections, with only 2 daily coaches between Middlesbrough and Southampton.

The busiest time of the day is the Morning, with 13 buses from Middlesbrough to Southampton, while Night sees the fewest connections between Middlesbrough and Southampton, with 4 offers.

Facts about the bus from Middlesbrough to Southampton

Compare all providers like National Express that travel 5 times every day by bus from Middlesbrough to Southampton in one click! Book your bus ticket from Middlesbrough to Southampton starting from $35!

Cheapest Bus	$35
Fastest Bus	9h 15m
Earliest Bus	1:25 PM
Latest Bus	11:00 AM
Daily Bus Routes	5 Ø
Distance	253.4 miles
Bus Companies	National Express

Cheapest bus connections from Middlesbrough to Southampton

Every day, 5 buses from 1 bus companies leave Middlesbrough for Southampton: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$53

Saturday 12/20

Sunday 12/21

$53

Monday 12/22

$56

Tuesday 12/23

$44

Wednesday 12/24

$57

Thursday 12/25

Friday 12/26

$80

Saturday 12/27

Sunday 12/28

$57

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Middlesbrough to Southampton

See here on which day and which time of the day you can find the cheapest bus ticket from Middlesbrough to Southampton, for the next 30 days.

With a price starting from $44, Tuesday is the cheapest day for a bus from Middlesbrough to Southampton. Wednesday instead is the most expensive day with prices starting from $57.

Night is the cheapest day time for bus tickets from Middlesbrough to Southampton, with $22. Morning is the most expensive time of the day with prices starting from $56.

How to save money travelling from Middlesbrough to Southampton

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Middlesbrough to Southampton in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Middlesbrough to Southampton, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Middlesbrough to Southampton are also emptier.

Beloved bus companies from Middlesbrough to Southampton

These are the most booked bus companies between Middlesbrough to Southampton from our users.

National Express from Middlesbrough to Southampton

Here you will find the key facts about the National Express bus route Middlesbrough to Southampton:

Cheapest Price	$44
Fastest Bus	9h 15m
Earliest Bus	1:25 PM
Last Bus	11:00 AM
Daily Connections	5 Ø
Found on	12/16/2025

All bus stations and stops in Middlesbrough and Southampton

In the map below, you can see where to find all bus stations in Middlesbrough and Southampton.

Bus Station

Newport Rd

Arriva Travel Shop

Cannon Park Way Bus Stop

Riverside Stadium

Bus Station

Harbour Parade 2

Solent University

East Park Terrace

University

Highfield Interchange Highfield Interchange

Port

Town Quay

New Road

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Middlesbrough to Southampton? Compare all modes of transports from Middlesbrough to Southampton.

Service and Comfort on the bus from Middlesbrough to Southampton

Want to know which seat classes are available on the buses from Middlesbrough to Southampton? Or which bus companies serve the route Middlesbrough to Southampton? Below you will find answers to your questions.

FAQs about the Middlesbrough to Southampton bus

How much does a Middlesbrough Southampton bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $35 and takes 10h 10m to reach Southampton. Compare offers to save money!

How much could I save by comparing buses from Middlesbrough to Southampton?

This route is offered by 1 companies with a range of ticket prices between $35 and $81. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Southampton.

On average, how many connections are available from Middlesbrough to Southampton each day?

Every day, the Middlesbrough to Southampton bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Middlesbrough to Southampton take?

The fastest bus from Middlesbrough to Southampton is offered by National Express and takes 9h 15m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Middlesbrough to Southampton?

The earliest bus arriving in Southampton from Middlesbrough starts at 1:25 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Middlesbrough to Southampton?

The latest bus trip departing from Middlesbrough for Southampton starts at 11:00 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Middlesbrough Southampton route?

When traveling by bus from Middlesbrough to Southampton, passengers can travel with National Express. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Middlesbrough and Southampton?

You can check all the direct connections between Middlesbrough and Southampton by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: National Express.

What can I take with me on the Middlesbrough to Southampton bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Middlesbrough Southampton bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Middlesbrough Southampton bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Middlesbrough to Southampton on your planned travel date.

How does CheckMyBus find the best bus deals from Middlesbrough to Southampton?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Middlesbrough and Southampton. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Middlesbrough to Southampton?

Prices and availability for 5 trips between Middlesbrough and Southampton change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Middlesbrough to Southampton

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Middlesbrough and to Southampton

Here’s an overview of the most popular bus routes to Middlesbrough and to Southampton. Simply click on the connection of your choice, and you will find all the details about your bus route!