Bus from Milan to Messina from $21

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Compare all timetables for the bus from Milan to Messina

Here is a selection of the cheapest bus trips from the schedule from Milan to Messina from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.
today
from $67
tomorrow
from $67
Monday
from $39
Tuesday
from $57
Wednesday
from $54
Thursday
from $21
Friday
from $48

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    17h 25m
    0
    12:55 PM
    Milan
    Lampugnano Bus Station
    6:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $67
  • FlixBus
    17h 15m
    0
    5:05 PM
    Milan
    San Donato Bus Station
    10:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $77
  • FlixBus
    18h 0m
    0
    4:20 PM
    Milan
    Lampugnano Bus Station
    10:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $78
  • MarinoBus
    20h 0m
    0
    8:40 AM
    Milan
    Lampugnano Bus Station
    4:40 AM
    Messina
    Central Station
    0
    MarinoBus
    Economy
    $99
  • Did you know that if you travel from Milan to Messina via San Donato Milanese, you can save more than $26? You will find the corresponding connections below.
    • Save more than 39%
      23h 15m
      Milan
      6 mi
      7:35 AM
      San Donato Milanese
      San Donato M3
      6:50 AM
      Messina
      Piazza della Repubblica
      0 mi
      Premium Economy
      $41
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $42? You can find the corresponding connections below.
    • Distribusion
      19h 40m
      0
      12:10 AM
      Milan
      Lampugnano Bus Station
      8:50 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      10h 55m
      0
      8:55 AM
      Rome
      Tiburtina Bus Station
      7:50 PM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $17
    Travel time is 2h 25m longer, but you will save $42

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    17h 25m
    0
    12:55 PM
    Milan
    Lampugnano Bus Station
    6:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $67
  • Itabus
    20h 25m
    0
    9:20 AM
    Milan
    Lampugnano Bus Station
    5:45 AM
    Messina
    Piazza della Repubblica
    0
    Itabus
    Premium Economy
    $68
  • FlixBus
    21h 10m
    0
    8:45 PM
    Milan
    Lampugnano Bus Station
    5:55 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $70
  • FlixBus
    20h 25m
    0
    9:30 PM
    Milan
    San Donato Bus Station
    5:55 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $70
  • Itabus
    20h 25m
    0
    9:20 AM
    Milan
    Lampugnano Bus Station
    5:45 AM
    Messina
    Piazza della Repubblica
    0
    Itabus
    Economy
    $84
  • Did you know that if you travel from Milan to Messina via San Donato Milanese, you can save more than $-3? You will find the corresponding connections below.
    • 23h 15m
      Milan
      6 mi
      7:35 AM
      San Donato Milanese
      San Donato M3
      6:50 AM
      Messina
      Piazza della Repubblica
      0 mi
      Economy
      $70
  • Did you know that if you travel from Villa San Giovanni to Milan via Messina, you can save more than $56? You will find the corresponding connections below.
    • Save more than 84%
      0h 59m
      0 mi
      5:51 AM
      Villa San Giovanni
      Station
      6:50 AM
      Messina
      Central Station
      600 mi
      Milan
      Premium Economy
      $11
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $42? You can find the corresponding connections below.
    • Distribusion
      19h 40m
      0
      12:10 AM
      Milan
      Lampugnano Bus Station
      8:50 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      10h 55m
      0
      8:55 AM
      Rome
      Tiburtina Bus Station
      7:50 PM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $17
    Travel time is 2h 15m longer, but you will save $42

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    19h 0m
    0
    3:30 PM
    Milan
    Lampugnano Bus Station
    10:30 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $39
  • FlixBus
    21h 5m
    0
    10:45 PM
    Milan
    Lampugnano Bus Station
    7:50 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $40
  • FlixBus
    20h 30m
    0
    11:20 PM
    Milan
    San Donato Bus Station
    7:50 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $41
  • FlixBus
    19h 20m
    0
    10:30 AM
    Milan
    Lampugnano Bus Station
    5:50 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $42
  • FlixBus
    20h 10m
    0
    9:40 AM
    Milan
    San Donato Bus Station
    5:50 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $46
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $14? You can find the corresponding connections below.
    • Distribusion
      19h 40m
      0
      12:10 AM
      Milan
      Lampugnano Bus Station
      8:50 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      10h 55m
      0
      8:55 AM
      Rome
      Tiburtina Bus Station
      7:50 PM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $17
    Travel time is 0h 40m longer, but you will save $14

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    17h 25m
    0
    12:55 PM
    Milan
    Lampugnano Bus Station
    6:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $57
  • FlixBus
    20h 30m
    0
    11:20 PM
    Milan
    San Donato Bus Station
    7:50 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $59
  • FlixBus
    21h 5m
    0
    10:45 PM
    Milan
    Lampugnano Bus Station
    7:50 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $60
  • FlixBus
    21h 30m
    0
    8:50 AM
    Milan
    San Donato Bus Station
    6:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $64
  • FlixBus
    18h 50m
    0
    3:30 PM
    Milan
    Lampugnano Bus Station
    10:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $65
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $32? You can find the corresponding connections below.
    • Distribusion
      19h 40m
      0
      12:10 AM
      Milan
      Lampugnano Bus Station
      8:50 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      10h 55m
      0
      8:55 AM
      Rome
      Tiburtina Bus Station
      7:50 PM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $17
    Travel time is 2h 15m longer, but you will save $32

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    17h 25m
    0
    12:55 PM
    Milan
    Lampugnano Bus Station
    6:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $54
  • FlixBus
    20h 40m
    0
    11:10 PM
    Milan
    San Donato Bus Station
    7:50 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $58
  • FlixBus
    21h 20m
    0
    10:30 PM
    Milan
    Lampugnano Bus Station
    7:50 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $59
  • FlixBus
    23h 25m
    0
    6:30 PM
    Milan
    San Donato Bus Station
    5:55 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $62
  • FlixBus
    20h 20m
    0
    3:30 PM
    Milan
    Lampugnano Bus Station
    11:50 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $63
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $29? You can find the corresponding connections below.
    • Distribusion
      19h 40m
      0
      12:10 AM
      Milan
      Lampugnano Bus Station
      8:50 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      10h 55m
      0
      8:55 AM
      Rome
      Tiburtina Bus Station
      7:50 PM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $17
    Travel time is 2h 15m longer, but you will save $29

Cheapest bus trips Thursday

Prices are for one way and one person
  • Itabus
    23h 20m
    0
    7:30 AM
    Milan
    San Donato Bus Station
    6:50 AM
    Messina
    Piazza della Repubblica
    0
    Itabus
    Economy
    $21
  • FlixBus
    20h 20m
    0
    3:30 PM
    Milan
    Lampugnano Bus Station
    11:50 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $32
  • Itabus
    20h 25m
    0
    9:20 AM
    Milan
    Lampugnano Bus Station
    5:45 AM
    Messina
    Central Station
    0
    Itabus
    Economy
    $37
  • FlixBus
    19h 20m
    0
    10:30 AM
    Milan
    Lampugnano Bus Station
    5:50 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $49
  • Autoservizi Salemi
    17h 55m
    0
    10:45 AM
    Milan
    San Donato Bus Station
    4:40 AM
    Messina
    Piazza della Repubblica
    0
    Autoservizi Salemi
    Economy
    $78

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    18h 50m
    0
    3:30 PM
    Milan
    Lampugnano Bus Station
    10:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $48
  • FlixBus
    17h 25m
    0
    12:55 PM
    Milan
    Lampugnano Bus Station
    6:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $60
  • FlixBus
    19h 35m
    0
    2:45 PM
    Milan
    San Donato Bus Station
    10:20 AM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $65
  • FlixBus
    21h 10m
    0
    8:45 PM
    Milan
    Lampugnano Bus Station
    5:55 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $73
  • FlixBus
    20h 25m
    0
    9:30 PM
    Milan
    San Donato Bus Station
    5:55 PM
    Messina
    Piazza della Repubblica
    0
    FlixBus
    Economy
    $73
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $23? You can find the corresponding connections below.
    • Distribusion
      19h 40m
      0
      12:10 AM
      Milan
      Lampugnano Bus Station
      8:50 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      10h 55m
      0
      8:55 AM
      Rome
      Tiburtina Bus Station
      7:50 PM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $17
    Travel time is 2h 15m longer, but you will save $23

Frequency of bus connections between Milan and Messina

See here how frequent the connections between Milan and Messina are, during different times and days of the week.
Thursday is the busiest day, with more than 15 daily buses from Milan to Messina. Tuesday has instead the fewest connections, with only 9 daily coaches between Milan and Messina.
The busiest time of the day is the Evening, with 26 buses from Milan to Messina, while Night sees the fewest connections between Milan and Messina, with 12 offers.

Facts about the bus from Milan to Messina

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 11 times every day by bus from Milan to Messina in one click! Book your bus ticket from Milan to Messina starting from $21!

Cheapest Bus $21
Fastest Bus 17h 15m
Earliest Bus 8:40 AM
Latest Bus 11:20 PM
Daily Bus Routes 11 Ø
Distance 599.7 miles
Bus Companies FlixBus, Itabus, Autoservizi Salemi and MarinoBus

Cheapest bus connections from Milan to Messina

Every day, 11 buses from 4 bus companies leave Milan for Messina: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/23/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/16
Monday 03/17
Tuesday 03/18
Wednesday 03/19
Thursday 03/20
Friday 03/21
Saturday 03/22
$67
Sunday 03/23
$56
Monday 03/24
$39
Tuesday 03/25
$57
Wednesday 03/26
$54
Thursday 03/27
$38
Friday 03/28
$48
Saturday 03/29
$41
Sunday 03/30
$46
Monday 03/31
$57
Tuesday 04/01
$33
Wednesday 04/02
$29
Thursday 04/03
$26
Friday 04/04
$36
Saturday 04/05
Sunday 04/06
$43
Monday 04/07
$35
Tuesday 04/08
Wednesday 04/09
$25
Thursday 04/10
$22
Friday 04/11
Saturday 04/12

The cheapest time to travel from Milan to Messina

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Messina, for the next 30 days.
With a price starting from $21, Thursday is the cheapest day for a bus from Milan to Messina. Sunday instead is the most expensive day with prices starting from $67.
Morning is the cheapest day time for bus tickets from Milan to Messina, with $21. Night is the most expensive time of the day with prices starting from $74.

How to save money travelling from Milan to Messina

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Messina in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Messina, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Messina are also emptier.

Beloved bus companies from Milan to Messina

These are the most booked bus companies between Milan to Messina from our users.

FlixBus from Milan to Messina

FlixBus

Here you will find the key facts about the FlixBus bus route Milan to Messina:

Cheapest Price $32
Fastest Bus 17h 15m
Earliest Bus 9:40 AM
Last Bus 11:20 PM
Daily Connections 9 Ø
Found on 3/20/2025

All bus stations and stops in Milan and Messina

In the map below, you can see where to find all bus stations in Milan and Messina.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Messina? Compare all modes of transports from Milan to Messina.

Service and Comfort on the bus from Milan to Messina

Want to know which seat classes are available on the buses from Milan to Messina? Or which bus companies serve the route Milan to Messina? Below you will find answers to your questions.

FAQs about the Milan to Messina bus

How much does a Milan Messina bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 23h 20m to reach Messina. Compare offers to save money!

How much could I save by comparing buses from Milan to Messina?

This route is offered by 4 companies with a range of ticket prices between $21 and $125. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Messina.

On average, how many connections are available from Milan to Messina each day?

Every day, the Milan to Messina bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Messina take?

The fastest bus from Milan to Messina is offered by FlixBus and takes 17h 15m. Bus tickets for this connection cost $77. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Messina?

The earliest bus arriving in Messina from Milan starts at 8:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Messina?

The latest bus trip departing from Milan for Messina starts at 11:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Messina route?

When traveling by bus from Milan to Messina, passengers can travel with FlixBus, Itabus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Messina?

You can check all the direct connections between Milan and Messina by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the Milan to Messina bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Messina bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Messina bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Messina on your planned travel date.

Available seat classes which are offered on the bus route Milan to Messina

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Messina

Here’s an overview of the most popular bus routes to Milan and to Messina. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Buses to Messina from Taormina Buses to Messina from Taormina
Bus Palermo to Messina Bus Palermo to Messina
Catania to Messina bus Catania to Messina bus
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Popular Airport Shuttles to Milan and to Messina
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