Compare all timetables for the bus from Milan to Siena
Cheapest bus trips today
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FlixBus5h 45m03:30 PMMilanLampugnano Bus Station9:15 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/1/2025 3:30:00 PM to Train Station, Siena (Italy) arriving at 5/1/2025 9:15:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 45m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/1/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/1/2025 6:35:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 0m
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Itabus8h 0m09:00 AMMilanLampugnano Bus Station5:00 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/1/2025 9:00:00 AM to Train Station, Siena (Italy) arriving at 5/1/2025 5:00:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 8h 0m
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FlixBus5h 35m02:25 PMMilanSan Donato Bus Station8:00 PMSienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 5/1/2025 2:25:00 PM to Train Station, Siena (Italy) arriving at 5/1/2025 8:00:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 35m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/1/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/1/2025 6:35:00 PM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 6h 0m
Cheapest bus trips tomorrow
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/2/2025 6:15:00 AM to Train Station, Siena (Italy) arriving at 5/2/2025 12:30:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 6h 15m
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FlixBus5h 50m012:25 PMMilanLampugnano Bus Station6:15 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/2/2025 12:25:00 PM to Train Station, Siena (Italy) arriving at 5/2/2025 6:15:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 5h 50m
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FlixBus5h 45m03:30 PMMilanLampugnano Bus Station9:15 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/2/2025 3:30:00 PM to Train Station, Siena (Italy) arriving at 5/2/2025 9:15:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 5h 45m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/2/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/2/2025 6:35:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 6h 0m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/2/2025 12:35:00 PM to Central Bus Station, Siena (Italy) arriving at 5/2/2025 6:35:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 0m
Cheapest bus trips Saturday
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Itabus5h 45m012:10 AMMilanLampugnano Bus Station5:55 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/3/2025 12:10:00 AM to Train Station, Siena (Italy) arriving at 5/3/2025 5:55:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 45m
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Itabus5h 45m012:10 AMMilanLampugnano Bus Station5:55 AMSienaTrain Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/3/2025 12:10:00 AM to Train Station, Siena (Italy) arriving at 5/3/2025 5:55:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 45m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/3/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/3/2025 6:35:00 PM. 50 Premium Economy ticket for $24 per person are available. Travel duration is 6h 0m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/3/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/3/2025 6:35:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 6h 0m
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Itabus13h 50m010:30 PMMilanLampugnano Bus Station12:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/3/2025 10:30:00 PM to Train Station, Siena (Italy) arriving at 5/4/2025 12:20:00 PM. 50 Premium Economy ticket for $94 per person are available. Travel duration is 13h 50m
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5h 0mMilan6 mi12:55 AMSan Donato MilaneseSan Donato M35:55 AMSienaTrain Station0 miEconomyA Bus from goes from San Donato M3, San Donato Milanese (Italy) at 5/3/2025 12:55:00 AM to Train Station, Siena (Italy) arriving at 5/3/2025 5:55:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 5h 0m
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Cheapest bus trips Sunday
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FlixBus5h 45m05:35 AMMilanLampugnano Bus Station11:20 AMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/4/2025 5:35:00 AM to Train Station, Siena (Italy) arriving at 5/4/2025 11:20:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/4/2025 6:15:00 AM to Train Station, Siena (Italy) arriving at 5/4/2025 12:30:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 15m
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FlixBus5h 40m06:50 AMMilanSan Donato Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 5/4/2025 6:50:00 AM to Train Station, Siena (Italy) arriving at 5/4/2025 12:30:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 40m
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Itabus7h 30m08:35 PMMilanLampugnano Bus Station4:05 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/4/2025 8:35:00 PM to Train Station, Siena (Italy) arriving at 5/5/2025 4:05:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 7h 30m
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Itabus8h 0m09:00 AMMilanLampugnano Bus Station5:00 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/4/2025 9:00:00 AM to Train Station, Siena (Italy) arriving at 5/4/2025 5:00:00 PM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 8h 0m
Cheapest bus trips Monday
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FlixBus6h 10m06:15 AMMilanLampugnano Bus Station12:25 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/5/2025 6:15:00 AM to Train Station, Siena (Italy) arriving at 5/5/2025 12:25:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 6h 10m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 5/5/2025 8:15:00 AM to Train Station, Siena (Italy) arriving at 5/5/2025 3:40:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 7h 25m
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FlixBus5h 35m06:50 AMMilanSan Donato Bus Station12:25 PMSienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 5/5/2025 6:50:00 AM to Train Station, Siena (Italy) arriving at 5/5/2025 12:25:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 5h 35m
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Itabus8h 0m09:00 AMMilanLampugnano Bus Station5:00 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/5/2025 9:00:00 AM to Central Bus Station, Siena (Italy) arriving at 5/5/2025 5:00:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 8h 0m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/5/2025 12:35:00 PM to Central Bus Station, Siena (Italy) arriving at 5/5/2025 6:35:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 0m
Cheapest bus trips Tuesday
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Itabus5h 45m012:10 AMMilanLampugnano Bus Station5:55 AMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/6/2025 12:10:00 AM to Central Bus Station, Siena (Italy) arriving at 5/6/2025 5:55:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 45m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/6/2025 12:35:00 PM to Central Bus Station, Siena (Italy) arriving at 5/6/2025 6:35:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 6h 0m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/6/2025 12:35:00 PM to Central Bus Station, Siena (Italy) arriving at 5/6/2025 6:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 0m
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Itabus5h 45m012:10 AMMilanLampugnano Bus Station5:55 AMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/6/2025 12:10:00 AM to Central Bus Station, Siena (Italy) arriving at 5/6/2025 5:55:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 45m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/6/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/6/2025 6:35:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 0m
Cheapest bus trips Wednesday
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/7/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/7/2025 6:35:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 0m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/7/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/7/2025 6:35:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 0m
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Itabus5h 45m012:10 AMMilanLampugnano Bus Station5:55 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/7/2025 12:10:00 AM to Train Station, Siena (Italy) arriving at 5/7/2025 5:55:00 AM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 5h 45m
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Itabus6h 0m012:35 PMMilanLampugnano Bus Station6:35 PMSienaTrain Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/7/2025 12:35:00 PM to Train Station, Siena (Italy) arriving at 5/7/2025 6:35:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 6h 0m
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Itabus5h 45m012:10 AMMilanLampugnano Bus Station5:55 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 5/7/2025 12:10:00 AM to Train Station, Siena (Italy) arriving at 5/7/2025 5:55:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 5h 45m
Frequency of bus connections between Milan and Siena
Facts about the bus from Milan to Siena
Compare all providers like FlixBus and Itabus that travel 14 times every day by bus from Milan to Siena in one click! Book your bus ticket from Milan to Siena starting from $11!
Cheapest Bus | $11 |
Fastest Bus | 4h 20m |
Earliest Bus | 1:10 AM |
Latest Bus | 12:35 PM |
Daily Bus Routes | 14 Ø |
Distance | 182.3 miles |
Bus Companies | FlixBus and Itabus |
Cheapest bus connections from Milan to Siena
Every day, 14 buses from 2 bus companies leave Milan for Siena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/01/2025 and for the following days.
The cheapest time to travel from Milan to Siena
How to save money travelling from Milan to Siena
Book the ticket from Milan to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Siena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Siena are also emptier.All bus stations and stops in Milan and Siena
In the map below, you can see where to find all bus stations in Milan and Siena.
Compare the bus with other modes of transport
Service and Comfort on the bus from Milan to Siena
FAQs about the Milan to Siena bus
How much does a Milan Siena bus trip cost?
How much could I save by comparing buses from Milan to Siena?
On average, how many connections are available from Milan to Siena each day?
How long does a bus journey from Milan to Siena take?
What time is the first bus from Milan to Siena?
What time is the last bus from Milan to Siena?
Which bus companies operate the Milan Siena route?
Is there a direct bus between Milan and Siena?
What can I take with me on the Milan to Siena bus route?
What equipment is available for the Milan Siena bus route?
Available seat classes which are offered on the bus route Milan to Siena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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