Bus Philadelphia to Charleston, SC: Compare prices and save money

Compare all timetables for the bus from Philadelphia to Charleston, SC

Here is a selection of the cheapest bus trips from the schedule from Philadelphia to Charleston, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Monday

$223

Tuesday

Wednesday

Thursday

Friday

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 30m	10:00 PM	Philadelphia	Spring Garden St Station	6:30 PM	Charleston, SC	Bus Station	Economy	$223	A Bus from FlixBus goes from Spring Garden St Station, Philadelphia (USA) at 12/22/2025 10:00:00 PM to Bus Station, Charleston, SC (USA) arriving at 12/23/2025 6:30:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 20h 30m
Greyhound US	22h 0m	8:30 PM	Philadelphia	Spring Garden St Station	6:30 PM	Charleston, SC	Bus Station	Economy	$224	A Bus from Greyhound US goes from Spring Garden St Station, Philadelphia (USA) at 12/22/2025 8:30:00 PM to Bus Station, Charleston, SC (USA) arriving at 12/23/2025 6:30:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 22h 0m
FlixBus	28h 30m	2:00 PM	Philadelphia	JFK & Broad	6:30 PM	Charleston, SC	Bus Station	Economy	$245	A Bus from FlixBus goes from JFK & Broad, Philadelphia (USA) at 12/22/2025 2:00:00 PM to Bus Station, Charleston, SC (USA) arriving at 12/23/2025 6:30:00 PM. 50 Economy ticket for $245 per person are available. Travel duration is 28h 30m
Greyhound US	22h 30m	8:00 PM	Philadelphia	IRS Building	6:30 PM	Charleston, SC	Bus Station	Economy	$268	A Bus from Greyhound US goes from IRS Building, Philadelphia (USA) at 12/22/2025 8:00:00 PM to Bus Station, Charleston, SC (USA) arriving at 12/23/2025 6:30:00 PM. 50 Economy ticket for $268 per person are available. Travel duration is 22h 30m

Did you know that if you travel from Philadelphia to Charleston, SC via Myrtle Beach, SC, you can save more than $97? You can find the corresponding connections below.
- Busbud
  
  22h 30m
  
  0
  
  8:00 PM
  
  Philadelphia
  Schuylkill Ave and Walnut Street
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $111
  
  A Bus from Busbud goes from Schuylkill Ave and Walnut Street, Philadelphia (USA) at 12/23/2025 8:00:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/24/2025 3:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 19h 50m
- FlixBus
  
  2h 25m
  
  0
  
  4:05 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  6:30 PM
  
  Charleston, SC
  Bus Station
  
  0
  
  Economy
  
  $15
  
  A Bus from FlixBus goes from Bus Stop, Myrtle Beach, SC (USA) at 12/24/2025 4:05:00 PM to Bus Station, Charleston, SC (USA) arriving at 12/24/2025 6:30:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 2h 25m
Travel time is 2h 0m longer, but you will save $97

Best Price Offer: The price for the cheapest bus from Philadelphia to Charleston, SC is $103 on 12/14/2025. Flexible travelers save on ticket prices.

Facts about the bus from Philadelphia to Charleston, SC

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Philadelphia to Charleston, SC in one click! Book your bus ticket from Philadelphia to Charleston, SC starting from $103!

Cheapest Bus	$103
Fastest Bus	20h 30m
Earliest Bus	2:00 PM
Latest Bus	10:00 PM
Daily Bus Routes	4 Ø
Distance	562.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Philadelphia to Charleston, SC

Every day, 4 buses from 2 bus companies leave Philadelphia for Charleston, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/20/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

$223

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

How to save money travelling from Philadelphia to Charleston, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Philadelphia to Charleston, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Philadelphia to Charleston, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Philadelphia to Charleston, SC are also emptier.

All bus stations and stops in Philadelphia and Charleston, SC

In the map below, you can see where to find all bus stations in Philadelphia and Charleston, SC.

Central Bus Station

Filbert St 1001

Market St

Spring Garden St Station

Spring Garden St & 2nd St

JFK & Broad

John F Kennedy Blvd 1401

30th Street Station

Market St 2955

Bus Station

Dorchester Rd 3610

BI-LO Shopping Center Downtown

Meeting St 445

Service and Comfort on the bus from Philadelphia to Charleston, SC

Want to know which seat classes are available on the buses from Philadelphia to Charleston, SC? Or which bus companies serve the route Philadelphia to Charleston, SC? Below you will find answers to your questions.

FAQs about the Philadelphia to Charleston, SC bus

How much does a Philadelphia Charleston, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $103 and takes 20h 30m to reach Charleston, SC. Compare offers to save money!

How much could I save by comparing buses from Philadelphia to Charleston, SC?

This route is offered by 2 companies with a range of ticket prices between $103 and $268. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charleston, SC.

On average, how many connections are available from Philadelphia to Charleston, SC each day?

Every day, the Philadelphia to Charleston, SC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Philadelphia to Charleston, SC take?

The fastest bus from Philadelphia to Charleston, SC is offered by FlixBus and takes 20h 30m. Bus tickets for this connection cost $223. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Philadelphia to Charleston, SC?

The earliest bus arriving in Charleston, SC from Philadelphia starts at 2:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Philadelphia to Charleston, SC?

The latest bus trip departing from Philadelphia for Charleston, SC starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Philadelphia Charleston, SC route?

When traveling by bus from Philadelphia to Charleston, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Philadelphia and Charleston, SC?

You can check all the direct connections between Philadelphia and Charleston, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Philadelphia to Charleston, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Philadelphia Charleston, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Philadelphia Charleston, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Philadelphia to Charleston, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Philadelphia to Charleston, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Philadelphia and Charleston, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Philadelphia to Charleston, SC?

Prices and availability for 4 trips between Philadelphia and Charleston, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Philadelphia to Charleston, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Philadelphia and to Charleston, SC

Here’s an overview of the most popular bus routes to Philadelphia and to Charleston, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!