Bus from Rome to Prague from $73

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Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus or RegioJet for the next days.
today
from $98
tomorrow
from $73
Monday
from $124
Tuesday
from $123
Wednesday
from $127
Thursday
from $105
Friday
from $104

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    25h 15m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    10:15 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $98
  • FlixBus
    20h 30m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:30 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $99
  • FlixBus
    26h 55m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    11:55 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $99
  • FlixBus
    20h 40m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:40 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $99
  • FlixBus
    22h 30m
    0
    10:15 AM
    Rome
    Tiburtina Bus Station
    8:45 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $105
  • Did you know that if you travel from Rome to Prague via Trieste, you can save more than $26? You can find the corresponding connections below.
    • Distribusion
      22h 15m
      0
      10:00 AM
      Rome
      Tiburtina Bus Station
      7:30 PM
      Trieste
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $28
      • Waiting Time 1h 45m
    • FlixBus
      11h 0m
      0
      9:15 PM
      Trieste
      Central Station
      8:15 AM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $43
    Travel time is 1h 45m longer, but you will save $26

Cheapest bus trips tomorrow

Prices are for one way and one person
  • RegioJet
    20h 10m
    0
    1:00 PM
    Rome
    Tiburtina Bus Station
    9:10 AM
    Prague
    ÚAN Florenc
    0
    RegioJet
    Economy
    $73
  • RegioJet
    20h 39m
    0
    1:00 PM
    Rome
    Tiburtina Bus Station
    9:39 AM
    Prague
    Wilsonova Bus Station
    0
    RegioJet
    Economy
    $82
  • FlixBus
    21h 30m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    10:35 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $124
  • FlixBus
    20h 20m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    9:25 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $124
  • FlixBus
    25h 10m
    0
    12:20 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $131

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    22h 45m
    0
    9:20 PM
    Rome
    Tiburtina Bus Station
    8:05 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $124
  • FlixBus
    22h 55m
    0
    9:20 PM
    Rome
    Tiburtina Bus Station
    8:15 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $124
  • FlixBus
    22h 15m
    0
    11:05 PM
    Rome
    Tiburtina Bus Station
    9:20 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $159
  • FlixBus
    23h 35m
    0
    11:05 PM
    Rome
    Tiburtina Bus Station
    10:40 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $159
  • FlixBus
    22h 50m
    0
    11:05 PM
    Rome
    Tiburtina Bus Station
    9:55 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $159
  • Did you know that if you travel from Rome to Prague via Trieste, you can save more than $52? You can find the corresponding connections below.
    • Distribusion
      22h 15m
      0
      10:00 AM
      Rome
      Tiburtina Bus Station
      7:30 PM
      Trieste
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $28
      • Waiting Time 1h 45m
    • FlixBus
      11h 0m
      0
      9:15 PM
      Trieste
      Central Station
      8:15 AM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $43
    Travel time is the same as the direct connection, but you will save $52

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    27h 40m
    0
    11:35 PM
    Rome
    Anagnina Bus Station
    3:15 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $123
  • FlixBus
    23h 35m
    0
    11:05 PM
    Rome
    Tiburtina Bus Station
    10:40 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $131
  • FlixBus
    22h 15m
    0
    11:05 PM
    Rome
    Tiburtina Bus Station
    9:20 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $132
  • FlixBus
    22h 50m
    0
    11:05 PM
    Rome
    Tiburtina Bus Station
    9:55 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $132
  • FlixBus
    22h 45m
    0
    9:20 PM
    Rome
    Tiburtina Bus Station
    8:05 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $142
  • Did you know that if you travel from Rome to Prague via Trieste, you can save more than $51? You can find the corresponding connections below.
    • Distribusion
      22h 15m
      0
      10:00 AM
      Rome
      Tiburtina Bus Station
      7:30 PM
      Trieste
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $28
      • Waiting Time 1h 45m
    • FlixBus
      11h 0m
      0
      9:15 PM
      Trieste
      Central Station
      8:15 AM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $43
    Travel time is the same as the direct connection, but you will save $51

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    25h 15m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    10:15 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $127
  • FlixBus
    20h 30m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:30 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $127
  • FlixBus
    26h 55m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    11:55 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $127
  • FlixBus
    20h 40m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:40 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $127
  • FlixBus
    23h 20m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    8:20 PM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $127
  • Did you know that if you travel from Rome to Prague via Trieste, you can save more than $55? You can find the corresponding connections below.
    • Distribusion
      22h 15m
      0
      10:00 AM
      Rome
      Tiburtina Bus Station
      7:30 PM
      Trieste
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $28
      • Waiting Time 1h 45m
    • FlixBus
      11h 0m
      0
      9:15 PM
      Trieste
      Central Station
      8:15 AM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $43
    Travel time is 1h 45m longer, but you will save $55

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    24h 25m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    1:30 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $105
  • FlixBus
    25h 10m
    0
    12:20 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $106
  • FlixBus
    22h 30m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    6:00 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $112
  • FlixBus
    22h 45m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    6:15 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $112
  • FlixBus
    27h 40m
    0
    11:35 PM
    Rome
    Anagnina Bus Station
    3:15 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $118
  • Did you know that if you travel from Rome to Prague via Trieste, you can save more than $33? You can find the corresponding connections below.
    • Distribusion
      22h 15m
      0
      10:00 AM
      Rome
      Tiburtina Bus Station
      7:30 PM
      Trieste
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $28
      • Waiting Time 1h 45m
    • FlixBus
      11h 0m
      0
      9:15 PM
      Trieste
      Central Station
      8:15 AM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $43
    Travel Time is 0h 15m shorter, and you will save $33

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    24h 25m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    1:30 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $104
  • FlixBus
    20h 30m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:30 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $113
  • FlixBus
    20h 40m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:40 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $113
  • FlixBus
    26h 55m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    11:55 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $114
  • FlixBus
    25h 15m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    10:15 PM
    Prague
    Roztyly
    0
    FlixBus
    Economy
    $114
  • Did you know that if you travel from Rome to Prague via Trieste, you can save more than $32? You can find the corresponding connections below.
    • Distribusion
      22h 15m
      0
      10:00 AM
      Rome
      Tiburtina Bus Station
      7:30 PM
      Trieste
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $28
      • Waiting Time 1h 45m
    • FlixBus
      11h 0m
      0
      9:15 PM
      Trieste
      Central Station
      8:15 AM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $43
    Travel time is 1h 45m longer, but you will save $32

Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Sunday is the busiest day, with more than 43 daily buses from Rome to Prague. Monday has instead the fewest connections, with only 33 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 107 buses from Rome to Prague, while Night sees the fewest connections between Rome and Prague, with 10 offers.

Facts about the bus from Rome to Prague

Compare all providers like FlixBus and RegioJet that travel 37 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from $73!

Cheapest Bus $73
Fastest Bus 19h 10m
Earliest Bus 1:40 AM
Latest Bus 11:35 PM
Daily Bus Routes 37 Ø
Distance 572.5 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Rome to Prague

Every day, 37 buses from 2 bus companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/13
Monday 04/14
Tuesday 04/15
Wednesday 04/16
Thursday 04/17
Friday 04/18
Saturday 04/19
$98
Sunday 04/20
$124
Monday 04/21
$124
Tuesday 04/22
$123
Wednesday 04/23
$127
Thursday 04/24
$105
Friday 04/25
$104
Saturday 04/26
$109
Sunday 04/27
$108
Monday 04/28
$93
Tuesday 04/29
$85
Wednesday 04/30
$106
Thursday 05/01
$80
Friday 05/02
$79
Saturday 05/03
$75
Sunday 05/04
$79
Monday 05/05
$71
Tuesday 05/06
$68
Wednesday 05/07
$70
Thursday 05/08
$69
Friday 05/09
$73
Saturday 05/10

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from $73, Sunday is the cheapest day for a bus from Rome to Prague. Wednesday instead is the most expensive day with prices starting from $127.
Afternoon is the cheapest day time for bus tickets from Rome to Prague, with $73. Night is the most expensive time of the day with prices starting from $129.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Prague are also emptier.

All bus stations and stops in Rome and Prague

In the map below, you can see where to find all bus stations in Rome and Prague.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Prague? Compare all modes of transports from Rome to Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the buses from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $73 and takes 20h 10m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Rome to Prague?

This route is offered by 2 companies with a range of ticket prices between $73 and $276. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Rome to Prague each day?

Every day, the Rome to Prague bus route is served by approximately 37 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Prague take?

The fastest bus from Rome to Prague is offered by FlixBus and takes 19h 10m. Bus tickets for this connection cost $132. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus arriving in Prague from Rome starts at 1:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Prague?

The latest bus trip departing from Rome for Prague starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Prague route?

When traveling by bus from Rome to Prague, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Rome to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Milan to Prague bus Milan to Prague bus
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Bus Vienna to Prague Bus Vienna to Prague
Popular Airport Shuttles to Rome and to Prague
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