Bus San Antonio, TX to San Diego: Compare prices and save money

Compare all timetables for the bus from San Antonio, TX to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to San Diego from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

from $178

tomorrow

Thursday

from $145

Friday

from $107

Saturday

from $160

Sunday

Monday

from $135

Cheapest bus trips today

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	41h 45m	6:05 AM	San Antonio, TX	Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$178	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 8/12/2025 6:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2025 11:50:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 41h 45m
Greyhound US	38h 5m	6:10 AM	San Antonio, TX	Bus Station	8:15 PM	San Diego	Old Town Transit Center	Economy	$180	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/12/2025 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2025 8:15:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 38h 5m
Greyhound US	39h 20m	6:10 AM	San Antonio, TX	Bus Station	9:30 PM	San Diego	Seaport Village	Economy	$182	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/12/2025 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 8/13/2025 9:30:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 39h 20m
FlixBus	38h 25m	6:20 PM	San Antonio, TX	Bus Station	8:45 AM	San Diego	La Jolla Village	Economy	$184	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/12/2025 6:20:00 PM to La Jolla Village, San Diego (USA) arriving at 8/14/2025 8:45:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 38h 25m
FlixBus	45h 20m	6:20 PM	San Antonio, TX	Bus Station	3:40 PM	San Diego	SDSU Transit Center	Economy	$184	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/12/2025 6:20:00 PM to SDSU Transit Center, San Diego (USA) arriving at 8/14/2025 3:40:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 45h 20m

Cheapest bus trips Thursday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 45m	6:20 PM	San Antonio, TX	Bus Station	10:05 AM	San Diego	San Ysidro Transit Center	Economy	$145	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/14/2025 6:20:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/16/2025 10:05:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 41h 45m
FlixBus	47h 20m	9:00 PM	San Antonio, TX	Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$149	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/14/2025 9:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/16/2025 6:20:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 47h 20m
Greyhound US	36h 0m	6:10 AM	San Antonio, TX	Bus Station	4:10 PM	San Diego	San Ysidro Transit Center	Economy	$161	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/14/2025 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/15/2025 4:10:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 36h 0m

Cheapest bus trips Friday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 30m	6:10 AM	San Antonio, TX	Bus Station	3:40 PM	San Diego	San Ysidro Transit Center	Economy	$107	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/15/2025 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/16/2025 3:40:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 33h 30m
Greyhound US	37h 35m	12:40 PM	San Antonio, TX	Bus Station	2:15 AM	San Diego	San Ysidro Transit Center	Economy	$121	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/15/2025 12:40:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/17/2025 2:15:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 37h 35m
FlixBus	39h 45m	6:20 PM	San Antonio, TX	Bus Station	10:05 AM	San Diego	San Ysidro Transit Center	Economy	$121	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/15/2025 6:20:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/17/2025 10:05:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 39h 45m

Cheapest bus trips Saturday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	47h 20m	9:00 PM	San Antonio, TX	Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$160	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/16/2025 9:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/18/2025 6:20:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 47h 20m
Greyhound US	36h 0m	6:10 AM	San Antonio, TX	Bus Station	4:10 PM	San Diego	San Ysidro Transit Center	Economy	$161	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/16/2025 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/17/2025 4:10:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 36h 0m
FlixBus	43h 30m	6:20 PM	San Antonio, TX	Bus Station	11:50 AM	San Diego	San Ysidro Transit Center	Economy	$164	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/16/2025 6:20:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/18/2025 11:50:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 43h 30m
Greyhound US	41h 20m	6:10 AM	San Antonio, TX	Bus Station	9:30 PM	San Diego	Seaport Village	Economy	$167	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/16/2025 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 8/17/2025 9:30:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 41h 20m
Greyhound Lines Mexico	37h 40m	6:05 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$169	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 8/16/2025 6:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/17/2025 5:45:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 37h 40m

Did you know that if you travel from San Antonio, TX to San Diego via El Paso, TX, you can save more than $21? You can find the corresponding connections below.
- FlixBus
  
  34h 0m
  
  0
  
  6:10 AM
  
  San Antonio, TX
  Bus Station
  
  3:35 PM
  
  El Paso, TX
  Bus Station
  
  0
  
  Economy
  
  $71
  
  A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/17/2025 6:10:00 AM to Bus Station, El Paso, TX (USA) arriving at 8/17/2025 3:35:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 9h 25m
- FlixBus
  
  23h 15m
  
  0
  
  4:55 PM
  
  El Paso, TX
  Bus Station
  
  4:10 PM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $68
  
  A Bus from FlixBus goes from Bus Station, El Paso, TX (USA) at 8/17/2025 4:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/18/2025 4:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 23h 15m
Travel time is the same as the direct connection, but you will save $21

Cheapest bus trips Monday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	48h 55m	7:15 PM	San Antonio, TX	Bus Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$135	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 8/18/2025 7:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/20/2025 6:10:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 48h 55m
Greyhound Lines Mexico	48h 20m	7:15 PM	San Antonio, TX	Bus Station	5:35 PM	San Diego	La Jolla Village	Economy	$136	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 8/18/2025 7:15:00 PM to La Jolla Village, San Diego (USA) arriving at 8/20/2025 5:35:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 48h 20m
Greyhound US	41h 20m	6:10 AM	San Antonio, TX	Bus Station	9:30 PM	San Diego	Seaport Village	Economy	$151	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/18/2025 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 8/19/2025 9:30:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 41h 20m
Greyhound US	39h 35m	6:10 AM	San Antonio, TX	Bus Station	7:45 PM	San Diego	La Jolla Village	Economy	$152	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/18/2025 6:10:00 AM to La Jolla Village, San Diego (USA) arriving at 8/19/2025 7:45:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 39h 35m
FlixBus	40h 55m	6:20 PM	San Antonio, TX	Bus Station	9:15 AM	San Diego	Old Town Transit Center	Economy	$159	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/18/2025 6:20:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/20/2025 9:15:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 40h 55m

Best Price Offer: The price for the cheapest bus from San Antonio, TX to San Diego is $107 on 8/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and San Diego

See here how frequent the connections between San Antonio, TX and San Diego are, during different times and days of the week.

Saturday is the busiest day, with more than 17 daily buses from San Antonio, TX to San Diego. Thursday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and San Diego.

The busiest time of the day is the Evening, with 27 buses from San Antonio, TX to San Diego, while Afternoon sees the fewest connections between San Antonio, TX and San Diego, with 1 offers.

Facts about the bus from San Antonio, TX to San Diego

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 10 times every day by bus from San Antonio, TX to San Diego in one click! Book your bus ticket from San Antonio, TX to San Diego starting from $107!

Cheapest Bus	$107
Fastest Bus	32h 40m
Earliest Bus	1:30 AM
Latest Bus	7:15 PM
Daily Bus Routes	10 Ø
Distance	1,126.5 miles
Bus Companies	FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from San Antonio, TX to San Diego

Every day, 10 buses from 3 bus companies leave San Antonio, TX for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/12/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/10

Monday 08/11

Tuesday 08/12

$193

Wednesday 08/13

Thursday 08/14

$145

Friday 08/15

$107

Saturday 08/16

$167

Sunday 08/17

Monday 08/18

$135

Tuesday 08/19

$155

Wednesday 08/20

$172

Thursday 08/21

Friday 08/22

Saturday 08/23

Sunday 08/24

Monday 08/25

Tuesday 08/26

Wednesday 08/27

Thursday 08/28

Friday 08/29

Saturday 08/30

Sunday 08/31

Monday 09/01

Tuesday 09/02

Wednesday 09/03

Thursday 09/04

Friday 09/05

Saturday 09/06

The cheapest time to travel from San Antonio, TX to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to San Diego, for the next 30 days.

With a price starting from $107, Friday is the cheapest day for a bus from San Antonio, TX to San Diego. Saturday instead is the most expensive day with prices starting from $160.

Morning is the cheapest day time for bus tickets from San Antonio, TX to San Diego, with $107. Evening is the most expensive time of the day with prices starting from $121.

How to save money travelling from San Antonio, TX to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to San Diego are also emptier.

All bus stations and stops in San Antonio, TX and San Diego

In the map below, you can see where to find all bus stations in San Antonio, TX and San Diego.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Urban Loop

W. Southcross & Buffalo Bus Stop

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Downtown

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from San Antonio, TX to San Diego

Want to know which seat classes are available on the buses from San Antonio, TX to San Diego? Or which bus companies serve the route San Antonio, TX to San Diego? Below you will find answers to your questions.

FAQs about the San Antonio, TX to San Diego bus

How much does a San Antonio, TX San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 33h 30m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to San Diego?

This route is offered by 3 companies with a range of ticket prices between $107 and $203. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Antonio, TX to San Diego each day?

Every day, the San Antonio, TX to San Diego bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to San Diego take?

The fastest bus from San Antonio, TX to San Diego is offered by Greyhound US and takes 32h 40m. Bus tickets for this connection cost $167. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to San Diego?

The earliest bus arriving in San Diego from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to San Diego?

The latest bus trip departing from San Antonio, TX for San Diego starts at 7:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX San Diego route?

When traveling by bus from San Antonio, TX to San Diego, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and San Diego?

You can check all the direct connections between San Antonio, TX and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to San Diego on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to San Diego

Here’s an overview of the most popular bus routes to San Antonio, TX and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!