Bus San Francisco to Santa Ana, CA: Compare prices and save money

Compare all timetables for the bus from San Francisco to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from San Francisco to Santa Ana, CA from various bus operators like Greyhound US or FlixBus for the next days.

today

from $56

tomorrow

Tuesday

Wednesday

Thursday

from $42

Friday

Saturday

Cheapest bus trips today

Prices are for one way and one person

Greyhound US

15h 30m

0

6:30 AM

San Francisco
Bus Station Transbay

10:00 PM

Santa Ana, CA
Bus Stop

0

Economy

$56

A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 4/27/2025 6:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 4/27/2025 10:00:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 15h 30m
Greyhound US

15h 35m

0

4:00 PM

San Francisco
Bus Station Transbay

7:35 AM

Santa Ana, CA
Bus Stop

0

Economy

$56

A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 4/27/2025 4:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 4/28/2025 7:35:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 15h 35m
FlixBus

12h 30m

0

9:30 AM

San Francisco
5th/Townsend

10:00 PM

Santa Ana, CA
Bus Stop

0

Economy

$56

A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 4/27/2025 9:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 4/27/2025 10:00:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 12h 30m
FlixBus

11h 0m

0

8:35 PM

San Francisco
5th/Townsend

7:35 AM

Santa Ana, CA
Bus Stop

0

Economy

$56

A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 4/27/2025 8:35:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 4/28/2025 7:35:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 11h 0m
FlixBus

10h 5m

0

11:25 PM

San Francisco
5th/Townsend

9:30 AM

Santa Ana, CA
Bus Stop

0

Economy

$57

A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 4/27/2025 11:25:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 4/28/2025 9:30:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 5m

Cheapest bus trips Thursday

Prices are for one way and one person

Greyhound US

15h 30m

0

6:30 AM

San Francisco
Bus Station Transbay

10:00 PM

Santa Ana, CA
Bus Stop

0

Economy

$42

A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 5/1/2025 6:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 5/1/2025 10:00:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 15h 30m
FlixBus

10h 5m

0

11:25 PM

San Francisco
5th/Townsend

9:30 AM

Santa Ana, CA
Bus Stop

0

Economy

$43

A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 5/1/2025 11:25:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 5/2/2025 9:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 5m
Greyhound US

15h 35m

0

4:00 PM

San Francisco
Bus Station Transbay

7:35 AM

Santa Ana, CA
Bus Stop

0

Economy

$51

A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 5/1/2025 4:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 5/2/2025 7:35:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 15h 35m
FlixBus

11h 0m

0

8:35 PM

San Francisco
5th/Townsend

7:35 AM

Santa Ana, CA
Bus Stop

0

Economy

$51

A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 5/1/2025 8:35:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 5/2/2025 7:35:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 0m
Greyhound US

10h 50m

0

10:40 PM

San Francisco
Bus Station Transbay

9:30 AM

Santa Ana, CA
Bus Stop

0

Economy

$59

A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 5/1/2025 10:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 5/2/2025 9:30:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 10h 50m

Frequency of bus connections between San Francisco and Santa Ana, CA

See here how frequent the connections between San Francisco and Santa Ana, CA are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from San Francisco to Santa Ana, CA. Thursday has instead the fewest connections, with only 5 daily coaches between San Francisco and Santa Ana, CA.

The busiest time of the day is the Evening, with 6 buses from San Francisco to Santa Ana, CA, while Afternoon sees the fewest connections between San Francisco and Santa Ana, CA, with 2 offers.

Facts about the bus from San Francisco to Santa Ana, CA

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from San Francisco to Santa Ana, CA in one click! Book your bus ticket from San Francisco to Santa Ana, CA starting from $42!

Cheapest Bus	$42
Fastest Bus	10h 5m
Earliest Bus	6:30 AM
Latest Bus	11:25 PM
Daily Bus Routes	5 Ø
Distance	376.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from San Francisco to Santa Ana, CA

Every day, 5 buses from 2 bus companies leave San Francisco for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/27

$56

Monday 04/28

Tuesday 04/29

Wednesday 04/30

Thursday 05/01

$42

Friday 05/02

Saturday 05/03

Sunday 05/04

Monday 05/05

Tuesday 05/06

$41

Wednesday 05/07

Thursday 05/08

Friday 05/09

Saturday 05/10

Sunday 05/11

Monday 05/12

Tuesday 05/13

Wednesday 05/14

Thursday 05/15

Friday 05/16

Saturday 05/17

Sunday 05/18

Monday 05/19

Tuesday 05/20

Wednesday 05/21

Thursday 05/22

Friday 05/23

Saturday 05/24

The cheapest time to travel from San Francisco to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to Santa Ana, CA, for the next 30 days.

With a price starting from $42, Thursday is the cheapest day for a bus from San Francisco to Santa Ana, CA. Sunday instead is the most expensive day with prices starting from $56.

Morning is the cheapest day time for bus tickets from San Francisco to Santa Ana, CA, with $42. Afternoon is the most expensive time of the day with prices starting from $51.

How to save money travelling from San Francisco to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Santa Ana, CA are also emptier.

All bus stations and stops in San Francisco and Santa Ana, CA

In the map below, you can see where to find all bus stations in San Francisco and Santa Ana, CA.

Bus Station Transbay

Folsom Street 200

South Van Ness Ave & Market St

5th/Townsend

Townsend St 400

Beach St & Hyde St

Union Square

Post St 470

Bus Stop

1000 E Santa Ana Blvd 105

Service and Comfort on the bus from San Francisco to Santa Ana, CA

Want to know which seat classes are available on the buses from San Francisco to Santa Ana, CA? Or which bus companies serve the route San Francisco to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the San Francisco to Santa Ana, CA bus

How much does a San Francisco Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 15h 30m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from San Francisco to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $42 and $64. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from San Francisco to Santa Ana, CA each day?

Every day, the San Francisco to Santa Ana, CA bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to Santa Ana, CA take?

The fastest bus from San Francisco to Santa Ana, CA is offered by FlixBus and takes 10h 5m. Bus tickets for this connection cost $57. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from San Francisco starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to Santa Ana, CA?

The latest bus trip departing from San Francisco for Santa Ana, CA starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco Santa Ana, CA route?

When traveling by bus from San Francisco to Santa Ana, CA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and Santa Ana, CA?

You can check all the direct connections between San Francisco and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Santa Ana, CA on your planned travel date.

Available seat classes which are offered on the bus route San Francisco to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to Santa Ana, CA

Here’s an overview of the most popular bus routes to San Francisco and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!