Bus from Santa Fe, SF to Mendoza from $70

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Compare all timetables for the bus from Santa Fe, SF to Mendoza

Here is a selection of the cheapest bus trips from the schedule from Santa Fe, SF to Mendoza from various bus operators like 20 de Junio, Andesmar or Flecha Bus for the next days.
today
from $70
tomorrow
from $70
Tuesday
from $70
Wednesday
from $72
Thursday
from $70
Friday
from $70
Saturday
from $70

Cheapest bus trips today

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $24

Cheapest bus trips tomorrow

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $24

Cheapest bus trips Tuesday

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • 20 de Junio
    15h 30m
    0
    5:30 PM
    Santa Fe, SF
    Central Bus Station
    9:00 AM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • Andesmar
    15h 45m
    0
    5:15 PM
    Santa Fe, SF
    Central Bus Station
    9:00 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Business
    $72
  • Andesmar
    15h 45m
    0
    5:15 PM
    Santa Fe, SF
    Central Bus Station
    9:00 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $24

Cheapest bus trips Wednesday

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $72
  • 20 de Junio
    15h 30m
    0
    5:30 PM
    Santa Fe, SF
    Central Bus Station
    9:00 AM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $26? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $26

Cheapest bus trips Thursday

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • 20 de Junio
    15h 30m
    0
    5:30 PM
    Santa Fe, SF
    Central Bus Station
    9:00 AM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $24

Cheapest bus trips Friday

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • 20 de Junio
    15h 30m
    0
    5:30 PM
    Santa Fe, SF
    Central Bus Station
    9:00 AM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $24

Cheapest bus trips Saturday

Prices are for one way and one person
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • 20 de Junio
    16h 10m
    0
    3:05 AM
    Santa Fe, SF
    Central Bus Station
    7:15 PM
    Mendoza
    Bus Station
    0
    20 de Junio
    Premium Economy
    $70
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Andesmar
    14h 52m
    0
    9:00 PM
    Santa Fe, SF
    Central Bus Station
    11:52 AM
    Mendoza
    Bus Station
    0
    Andesmar
    Premium Economy
    $72
  • Flecha Bus
    14h 20m
    0
    6:30 AM
    Santa Fe, SF
    Central Bus Station
    8:50 PM
    Mendoza
    Bus Station
    0
    Flecha Bus
    Premium Economy
    $79
  • Did you know that if you travel from Santa Fe, SF to Mendoza via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
    • Voyenbus
      20h 20m
      0
      3:05 AM
      Santa Fe, SF
      Central Bus Station
      8:35 AM
      Córdoba, CD
      Bus Station
      0
      Voyenbus
      Premium Economy
      $19
      • Waiting Time 4h 25m
    • Plataforma 10
      10h 25m
      0
      1:00 PM
      Córdoba, CD
      Bus Station
      11:25 PM
      Mendoza
      Bus Station
      0
      Plataforma 10
      Basic
      $27
    Travel time is 6h 0m longer, but you will save $24

Frequency of bus connections between Santa Fe, SF and Mendoza

See here how frequent the connections between Santa Fe, SF and Mendoza are, during different times and days of the week.
Friday is the busiest day, with more than 20 daily buses from Santa Fe, SF to Mendoza. Sunday has instead the fewest connections, with only 12 daily coaches between Santa Fe, SF and Mendoza.
The busiest time of the day is the Night, with 34 buses from Santa Fe, SF to Mendoza, while Morning sees the fewest connections between Santa Fe, SF and Mendoza, with 14 offers.

Facts about the bus from Santa Fe, SF to Mendoza

Compare all providers like 20 de Junio, Andesmar and Flecha Bus that travel 15 times every day by bus from Santa Fe, SF to Mendoza in one click! Book your bus ticket from Santa Fe, SF to Mendoza starting from $70!

Cheapest Bus $70
Fastest Bus 14h 20m
Earliest Bus 3:05 AM
Latest Bus 9:00 PM
Daily Bus Routes 15 Ø
Distance 484.2 miles
Bus Companies 20 de Junio, Andesmar and Flecha Bus

Cheapest bus connections from Santa Fe, SF to Mendoza

Every day, 15 buses from 3 bus companies leave Santa Fe, SF for Mendoza: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/11/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
$70
Monday 05/12
$70
Tuesday 05/13
$70
Wednesday 05/14
$72
Thursday 05/15
$70
Friday 05/16
$70
Saturday 05/17
$70
Sunday 05/18
$72
Monday 05/19
$72
Tuesday 05/20
$70
Wednesday 05/21
$70
Thursday 05/22
$70
Friday 05/23
$70
Saturday 05/24
$70
Sunday 05/25
Monday 05/26
$70
Tuesday 05/27
Wednesday 05/28
$70
Thursday 05/29
$70
Friday 05/30
Saturday 05/31
$70
Sunday 06/01
$70
Monday 06/02
Tuesday 06/03
$70
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07

The cheapest time to travel from Santa Fe, SF to Mendoza

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Fe, SF to Mendoza, for the next 30 days.
With a price starting from $70, Sunday is the cheapest day for a bus from Santa Fe, SF to Mendoza. Wednesday instead is the most expensive day with prices starting from $72.
Afternoon is the cheapest day time for bus tickets from Santa Fe, SF to Mendoza, with $70. Morning is the most expensive time of the day with prices starting from $79.

How to save money travelling from Santa Fe, SF to Mendoza

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Fe, SF to Mendoza in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Fe, SF to Mendoza, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Fe, SF to Mendoza are also emptier.

All bus stations and stops in Santa Fe, SF and Mendoza

In the map below, you can see where to find all bus stations in Santa Fe, SF and Mendoza.

Service and Comfort on the bus from Santa Fe, SF to Mendoza

Want to know which seat classes are available on the buses from Santa Fe, SF to Mendoza? Or which bus companies serve the route Santa Fe, SF to Mendoza? Below you will find answers to your questions.

FAQs about the Santa Fe, SF to Mendoza bus

How much does a Santa Fe, SF Mendoza bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $70 and takes 16h 10m to reach Mendoza. Compare offers to save money!

How much could I save by comparing buses from Santa Fe, SF to Mendoza?

This route is offered by 3 companies with a range of ticket prices between $70 and $91. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mendoza.

On average, how many connections are available from Santa Fe, SF to Mendoza each day?

Every day, the Santa Fe, SF to Mendoza bus route is served by approximately 15 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Fe, SF to Mendoza take?

The fastest bus from Santa Fe, SF to Mendoza is offered by Flecha Bus and takes 14h 20m. Bus tickets for this connection cost $79. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Fe, SF to Mendoza?

The earliest bus arriving in Mendoza from Santa Fe, SF starts at 3:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Fe, SF to Mendoza?

The latest bus trip departing from Santa Fe, SF for Mendoza starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Fe, SF Mendoza route?

When traveling by bus from Santa Fe, SF to Mendoza, passengers can travel with 20 de Junio, Andesmar and Flecha Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Fe, SF and Mendoza?

You can check all the direct connections between Santa Fe, SF and Mendoza by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: 20 de Junio, Andesmar and Flecha Bus.

What can I take with me on the Santa Fe, SF to Mendoza bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Fe, SF Mendoza bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Fe, SF Mendoza bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Fe, SF to Mendoza on your planned travel date.

Available seat classes which are offered on the bus route Santa Fe, SF to Mendoza

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

More bus routes to Santa Fe, SF and to Mendoza

Here’s an overview of the most popular bus routes to Santa Fe, SF and to Mendoza. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buenos Aires to Santa Fe, SF bus Buenos Aires to Santa Fe, SF bus
Bus Córdoba, CD - Santa Fe, SF Bus Córdoba, CD - Santa Fe, SF
Buses Florianópolis, SC to Santa Fe, SF Buses Florianópolis, SC to Santa Fe, SF
Buses San Nicolas de los Arroyos - Santa Fe, SF Buses San Nicolas de los Arroyos - Santa Fe, SF
From San Rafael, MZ to Mendoza bus From San Rafael, MZ to Mendoza bus
Buses Puerto Madryn to Mendoza Buses Puerto Madryn to Mendoza
Bus Penitentes to Mendoza Bus Penitentes to Mendoza
From Santiago, RM to Mendoza bus From Santiago, RM to Mendoza bus
Popular Airport Shuttles to Santa Fe, SF and to Mendoza
CheckMyBus › Buses in Argentina › Bus to Santa Fe, SF › Bus to Mendoza

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