Bus from Santiago del Estero to Buenos Aires from $45

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Compare all timetables for the bus from Santiago del Estero to Buenos Aires

Here is a selection of the cheapest bus trips from the schedule from Santiago del Estero to Buenos Aires from various bus operators like Balut, Vosa or Flecha Bus for the next days.
today
from $56
tomorrow
from $45
Wednesday
from $56
Thursday
from $56
Friday
from $56
Saturday
from $56
Sunday
from $56

Cheapest bus trips today

Prices are for one way and one person
  • 20 de Junio
    16h 15m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Expreso del Oeste
    15h 20m
    0
    8:25 PM
    Santiago del Estero
    Central Bus Station
    11:45 AM
    Buenos Aires
    Liniers Bus Station
    0
    Expreso del Oeste
    Premium Economy
    $56
  • Balut
    13h 35m
    0
    1:40 AM
    Santiago del Estero
    Central Bus Station
    3:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    Balut
    Premium Economy
    $60
  • Rutatlántica
    15h 20m
    0
    5:00 PM
    Santiago del Estero
    Central Bus Station
    8:20 AM
    Buenos Aires
    Julio A. Roca Bus Stop
    0
    Rutatlántica
    Premium Economy
    $63
  • Vosa
    12h 25m
    0
    7:50 PM
    Santiago del Estero
    Central Bus Station
    8:15 AM
    Buenos Aires
    Terminal Ómnibus Campana
    0
    Vosa
    Premium Economy
    $63

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Flecha Bus
    16h 50m
    0
    12:40 AM
    Santiago del Estero
    Central Bus Station
    5:30 PM
    Buenos Aires
    Terminal de Ómnibus Dellepiane
    0
    Flecha Bus
    Premium Economy
    $45
  • 20 de Junio
    16h 50m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:50 PM
    Buenos Aires
    Retiro Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Transporte La Union
    17h 50m
    0
    12:30 PM
    Santiago del Estero
    Central Bus Station
    6:20 AM
    Buenos Aires
    Liniers Bus Station
    0
    Transporte La Union
    Premium Economy
    $56
  • Vía Tac
    14h 20m
    0
    12:20 AM
    Santiago del Estero
    Central Bus Station
    2:40 PM
    Buenos Aires
    Retiro Bus Station
    0
    Vía Tac
    Premium Economy
    $60
  • Balut
    15h 0m
    0
    1:40 AM
    Santiago del Estero
    Central Bus Station
    4:40 PM
    Buenos Aires
    Retiro Bus Station
    0
    Balut
    Premium Economy
    $60

Cheapest bus trips Wednesday

Prices are for one way and one person
  • 20 de Junio
    16h 15m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Transporte La Union
    17h 50m
    0
    12:30 PM
    Santiago del Estero
    Central Bus Station
    6:20 AM
    Buenos Aires
    Liniers Bus Station
    0
    Transporte La Union
    Premium Economy
    $56
  • Balut
    13h 35m
    0
    1:40 AM
    Santiago del Estero
    Central Bus Station
    3:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    Balut
    Premium Economy
    $60
  • Vosa
    12h 25m
    0
    7:50 PM
    Santiago del Estero
    Central Bus Station
    8:15 AM
    Buenos Aires
    Terminal Ómnibus Campana
    0
    Vosa
    Premium Economy
    $63
  • Flecha Bus
    14h 0m
    0
    8:10 PM
    Santiago del Estero
    Central Bus Station
    10:10 AM
    Buenos Aires
    Terminal Ómnibus Campana
    0
    Flecha Bus
    Premium Economy
    $63

Cheapest bus trips Thursday

Prices are for one way and one person
  • 20 de Junio
    16h 50m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:50 PM
    Buenos Aires
    Retiro Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Vía Tac
    15h 25m
    0
    12:20 AM
    Santiago del Estero
    Central Bus Station
    3:45 PM
    Buenos Aires
    Terminal de Ómnibus Dellepiane
    0
    Vía Tac
    Premium Economy
    $60
  • Balut
    13h 50m
    0
    1:40 AM
    Santiago del Estero
    Central Bus Station
    3:30 PM
    Buenos Aires
    Terminal de Ómnibus Dellepiane
    0
    Balut
    Premium Economy
    $60
  • Vosa
    12h 25m
    0
    7:50 PM
    Santiago del Estero
    Central Bus Station
    8:15 AM
    Buenos Aires
    Terminal Ómnibus Campana
    0
    Vosa
    Premium Economy
    $63
  • Rutatlántica
    15h 20m
    0
    5:00 PM
    Santiago del Estero
    Central Bus Station
    8:20 AM
    Buenos Aires
    Julio A. Roca Bus Stop
    0
    Rutatlántica
    Premium Economy
    $63

Cheapest bus trips Friday

Prices are for one way and one person
  • 20 de Junio
    16h 50m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:50 PM
    Buenos Aires
    Retiro Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Transporte La Union
    17h 50m
    0
    12:30 PM
    Santiago del Estero
    Central Bus Station
    6:20 AM
    Buenos Aires
    Liniers Bus Station
    0
    Transporte La Union
    Premium Economy
    $56
  • Vía Tac
    14h 20m
    0
    12:20 AM
    Santiago del Estero
    Central Bus Station
    2:40 PM
    Buenos Aires
    Retiro Bus Station
    0
    Vía Tac
    Premium Economy
    $60
  • Balut
    15h 0m
    0
    1:40 AM
    Santiago del Estero
    Central Bus Station
    4:40 PM
    Buenos Aires
    Retiro Bus Station
    0
    Balut
    Premium Economy
    $60
  • Flecha Bus
    14h 0m
    0
    8:10 PM
    Santiago del Estero
    Central Bus Station
    10:10 AM
    Buenos Aires
    Terminal Ómnibus Campana
    0
    Flecha Bus
    Premium Economy
    $63

Cheapest bus trips Saturday

Prices are for one way and one person
  • 20 de Junio
    16h 15m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Expreso del Oeste
    14h 50m
    0
    8:25 PM
    Santiago del Estero
    Central Bus Station
    11:15 AM
    Buenos Aires
    Liniers Bus Station
    0
    Expreso del Oeste
    Premium Economy
    $56
  • La Unión
    18h 0m
    0
    12:30 PM
    Santiago del Estero
    Central Bus Station
    6:30 AM
    Buenos Aires
    Retiro Bus Station
    0
    La Unión
    Business
    $56
  • Transporte La Union
    17h 50m
    0
    12:30 PM
    Santiago del Estero
    Central Bus Station
    6:20 AM
    Buenos Aires
    Liniers Bus Station
    0
    Transporte La Union
    Premium Economy
    $56
  • Vía Tac
    15h 10m
    0
    12:20 AM
    Santiago del Estero
    Central Bus Station
    3:30 PM
    Buenos Aires
    Liniers Bus Station
    0
    Vía Tac
    Premium Economy
    $60

Cheapest bus trips Sunday

Prices are for one way and one person
  • 20 de Junio
    16h 15m
    0
    1:00 AM
    Santiago del Estero
    Central Bus Station
    5:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    20 de Junio
    Premium Economy
    $56
  • Transporte La Union
    17h 50m
    0
    12:30 PM
    Santiago del Estero
    Central Bus Station
    6:20 AM
    Buenos Aires
    Liniers Bus Station
    0
    Transporte La Union
    Premium Economy
    $56
  • Vía Tac
    15h 10m
    0
    12:20 AM
    Santiago del Estero
    Central Bus Station
    3:30 PM
    Buenos Aires
    Liniers Bus Station
    0
    Vía Tac
    Premium Economy
    $60
  • Balut
    13h 35m
    0
    1:40 AM
    Santiago del Estero
    Central Bus Station
    3:15 PM
    Buenos Aires
    Liniers Bus Station
    0
    Balut
    Premium Economy
    $60
  • Rutatlántica
    15h 20m
    0
    5:00 PM
    Santiago del Estero
    Central Bus Station
    8:20 AM
    Buenos Aires
    Julio A. Roca Bus Stop
    0
    Rutatlántica
    Premium Economy
    $63

Frequency of bus connections between Santiago del Estero and Buenos Aires

See here how frequent the connections between Santiago del Estero and Buenos Aires are, during different times and days of the week.
Monday is the busiest day, with more than 75 daily buses from Santiago del Estero to Buenos Aires. Wednesday has instead the fewest connections, with only 34 daily coaches between Santiago del Estero and Buenos Aires.
The busiest time of the day is the Night, with 190 buses from Santiago del Estero to Buenos Aires, while Afternoon sees the fewest connections between Santiago del Estero and Buenos Aires, with 76 offers.

Facts about the bus from Santiago del Estero to Buenos Aires

Compare all providers like Balut, Vosa and Flecha Bus that travel 53 times every day by bus from Santiago del Estero to Buenos Aires in one click! Book your bus ticket from Santiago del Estero to Buenos Aires starting from $45!

Cheapest Bus $45
Fastest Bus 12h 25m
Earliest Bus 1:00 AM
Latest Bus 11:05 PM
Daily Bus Routes 53 Ø
Distance 586.1 miles
Bus Companies Balut, Vosa, Flecha Bus, 20 de Junio, Rutatlántica, Vía Tac, Almirante Brown, Expreso del Oeste, La Veloz del Norte, Vía Bariloche and 5 more.

Cheapest bus connections from Santiago del Estero to Buenos Aires

Every day, 53 buses from 15 bus companies leave Santiago del Estero for Buenos Aires: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/31/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/30
Monday 03/31
$44
Tuesday 04/01
$45
Wednesday 04/02
$56
Thursday 04/03
$56
Friday 04/04
$44
Saturday 04/05
$56
Sunday 04/06
$44
Monday 04/07
$60
Tuesday 04/08
$56
Wednesday 04/09
$60
Thursday 04/10
$56
Friday 04/11
$56
Saturday 04/12
$44
Sunday 04/13
$56
Monday 04/14
$56
Tuesday 04/15
$66
Wednesday 04/16
$56
Thursday 04/17
$56
Friday 04/18
$56
Saturday 04/19
$56
Sunday 04/20
$44
Monday 04/21
$56
Tuesday 04/22
$56
Wednesday 04/23
$56
Thursday 04/24
$63
Friday 04/25
$60
Saturday 04/26

The cheapest time to travel from Santiago del Estero to Buenos Aires

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago del Estero to Buenos Aires, for the next 30 days.
With a price starting from $45, Tuesday is the cheapest day for a bus from Santiago del Estero to Buenos Aires. Thursday instead is the most expensive day with prices starting from $56.
Night is the cheapest day time for bus tickets from Santiago del Estero to Buenos Aires, with $45. Afternoon is the most expensive time of the day with prices starting from $56.

How to save money travelling from Santiago del Estero to Buenos Aires

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago del Estero to Buenos Aires in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago del Estero to Buenos Aires, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago del Estero to Buenos Aires are also emptier.

All bus stations and stops in Santiago del Estero and Buenos Aires

In the map below, you can see where to find all bus stations in Santiago del Estero and Buenos Aires.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago del Estero to Buenos Aires? Compare all modes of transports from Santiago del Estero to Buenos Aires.

Service and Comfort on the bus from Santiago del Estero to Buenos Aires

Want to know which seat classes are available on the buses from Santiago del Estero to Buenos Aires? Or which bus companies serve the route Santiago del Estero to Buenos Aires? Below you will find answers to your questions.

FAQs about the Santiago del Estero to Buenos Aires bus

How much does a Santiago del Estero Buenos Aires bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $45 and takes 16h 50m to reach Buenos Aires. Compare offers to save money!

How much could I save by comparing buses from Santiago del Estero to Buenos Aires?

This route is offered by 15 companies with a range of ticket prices between $45 and $103. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buenos Aires.

On average, how many connections are available from Santiago del Estero to Buenos Aires each day?

Every day, the Santiago del Estero to Buenos Aires bus route is served by approximately 53 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago del Estero to Buenos Aires take?

The fastest bus from Santiago del Estero to Buenos Aires is offered by Vosa and takes 12h 25m. Bus tickets for this connection cost $80. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago del Estero to Buenos Aires?

The earliest bus arriving in Buenos Aires from Santiago del Estero starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago del Estero to Buenos Aires?

The latest bus trip departing from Santiago del Estero for Buenos Aires starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago del Estero Buenos Aires route?

When traveling by bus from Santiago del Estero to Buenos Aires, passengers can travel with Balut, Vosa and Flecha Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago del Estero and Buenos Aires?

You can check all the direct connections between Santiago del Estero and Buenos Aires by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Balut, Vosa and Flecha Bus.

What can I take with me on the Santiago del Estero to Buenos Aires bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago del Estero Buenos Aires bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago del Estero Buenos Aires bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago del Estero to Buenos Aires on your planned travel date.

Available seat classes which are offered on the bus route Santiago del Estero to Buenos Aires

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

More bus routes to Santiago del Estero and to Buenos Aires

Here’s an overview of the most popular bus routes to Santiago del Estero and to Buenos Aires. Simply click on the connection of your choice, and you will find all the details about your bus route!
From San Miguel de Tucumán to Santiago del Estero bus From San Miguel de Tucumán to Santiago del Estero bus
Bus Rosario, SF - Santiago del Estero Bus Rosario, SF - Santiago del Estero
Bus from Termas de Río Hondo to Santiago del Estero Bus from Termas de Río Hondo to Santiago del Estero
Buses El Talar to Santiago del Estero Buses El Talar to Santiago del Estero
Bus to Buenos Aires from Santiago, RM Bus to Buenos Aires from Santiago, RM
Buses Asunción, PY - Buenos Aires Buses Asunción, PY - Buenos Aires
Bus Córdoba, CD to Buenos Aires Bus Córdoba, CD to Buenos Aires
Bus São Paulo to Buenos Aires Bus São Paulo to Buenos Aires
Popular Airport Shuttles to Santiago del Estero and to Buenos Aires
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