How to get from Antofagasta to Santiago, RM

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What is the best way to travel from Antofagasta to Santiago, RM?

Looking for a trip? Compare all the available Buses and Flights for the journey to Santiago, RM from Antofagasta. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 9 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
17h 0m
$24
$33
85
Flight
1h 52m
$25
$51
36

What is the cheapest way to reach Santiago, RM from Antofagasta?

You can get to Santiago, RM with just $24 by taking a Bus from Cikbus Elité, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Tuesday
from $24
Wednesday
from $31
Thursday
from $30
Friday
from $25
Saturday
from $31
Sunday
from $31
Monday
from $31

    Cheapest Buses Tuesday

  • Cikbus Elité
    18h 50m
    0
    3:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $24
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Cormar Bus
    18h 11m
    0
    11:59 PM
    Antofagasta
    Camus Bus Station
    6:10 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    $35
  • Cheapest Flights Tuesday

  • JetSmart
    1h 52m
    0
    8:36 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:28 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $48
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $48
  • LAN Perú
    1h 52m
    0
    7:19 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:11 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $54
  • LAN Perú
    1h 52m
    0
    8:49 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:41 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $54
  • LAN Airlines
    1h 52m
    0
    7:50 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:42 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $54

    Cheapest Buses Wednesday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    19h 15m
    0
    11:30 AM
    Antofagasta
    Camus Bus Station
    6:45 AM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cheapest Flights Wednesday

  • LAN Perú
    1h 52m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:51 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $43
  • JetSmart
    1h 52m
    0
    10:35 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:27 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $48
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $51
  • Sky Airline
    1h 56m
    0
    11:25 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:21 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $53
  • LAN Perú
    1h 52m
    0
    7:18 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:10 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $68

    Cheapest Buses Thursday

  • Cikbus Elité
    17h 45m
    0
    2:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:30 AM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Cormar Bus
    18h 11m
    0
    11:59 PM
    Antofagasta
    Camus Bus Station
    6:10 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    $32
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Cheapest Flights Thursday

  • Sky Airline
    1h 56m
    0
    2:13 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    4:09 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $65
  • LAN Airlines
    1h 52m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:51 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $70
  • Sky Airline
    25h 47m
    0
    9:53 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:40 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $73
  • LAN Airlines
    22h 3m
    0
    1:37 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:40 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $74
  • JetSmart
    1h 52m
    0
    8:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:51 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $76

    Cheapest Flights Friday

  • LAN Perú
    1h 52m
    0
    8:04 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:56 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $25
  • Sky Airline
    1h 56m
    0
    9:23 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:19 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • LAN Airlines
    1h 52m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:51 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $44
  • JetSmart
    1h 52m
    0
    3:52 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    5:44 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • JetSmart
    11h 15m
    0
    12:00 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:15 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $45
  • Cheapest Buses Friday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37

    Cheapest Buses Saturday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37

    Cheapest Buses Sunday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Cormar Bus
    18h 11m
    0
    11:59 PM
    Antofagasta
    Camus Bus Station
    6:10 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    $32
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
  • Cheapest Flights Sunday

  • LAN Airlines
    1h 52m
    0
    7:19 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:11 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $42
  • LAN Perú
    1h 52m
    0
    8:15 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:07 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $42
  • JetSmart
    1h 52m
    0
    7:18 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:10 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • Sky Airline
    1h 56m
    0
    8:38 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:34 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • LAN Airlines
    1h 52m
    0
    10:39 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:31 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $46

    Cheapest Buses Monday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cheapest Flights Monday

  • Sky Airline
    1h 56m
    0
    7:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:32 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • Sky Airline
    1h 56m
    0
    10:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:32 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • JetSmart
    1h 52m
    0
    11:51 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:43 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • JetSmart
    1h 52m
    0
    6:28 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    8:20 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • LAN Perú
    1h 52m
    0
    7:16 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:08 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $46

What are the fastest trips from Antofagasta to Santiago, RM?

You can get to Santiago, RM from Antofagasta in just 1h 52m with a Flight from JetSmart. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Tuesday
from 1h 52m
Wednesday
from 1h 52m
Thursday
from 1h 52m
Friday
from 1h 52m
Saturday
from 17h 0m
Sunday
from 1h 52m
Monday
from 1h 52m

    Fastest Flights Tuesday

  • JetSmart
    1h 52m
    0
    8:36 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:28 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $48
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $48
  • LAN Perú
    1h 52m
    0
    7:19 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:11 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $54
  • LAN Perú
    1h 52m
    0
    8:49 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:41 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $54
  • LAN Airlines
    1h 52m
    0
    7:50 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:42 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $54
  • Fastest Buses Tuesday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Cormar Bus
    18h 11m
    0
    11:59 PM
    Antofagasta
    Camus Bus Station
    6:10 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    $35
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Cikbus Elité
    18h 50m
    0
    3:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $24

    Fastest Flights Wednesday

  • LAN Perú
    1h 52m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:51 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $43
  • JetSmart
    1h 52m
    0
    10:35 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:27 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $48
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $51
  • LAN Perú
    1h 52m
    0
    7:18 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:10 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $68
  • Sky Airline
    1h 56m
    0
    11:25 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:21 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $53
  • Fastest Buses Wednesday

  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    19h 15m
    0
    11:30 AM
    Antofagasta
    Camus Bus Station
    6:45 AM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37

    Fastest Flights Thursday

  • LAN Airlines
    1h 52m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:51 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $70
  • JetSmart
    1h 52m
    0
    8:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:51 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $76
  • Sky Airline
    1h 56m
    0
    2:13 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    4:09 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $65
  • LAN Airlines
    22h 3m
    0
    1:37 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:40 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $74
  • Sky Airline
    25h 47m
    0
    9:53 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:40 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $73
  • Fastest Buses Thursday

  • Cikbus Elité
    17h 45m
    0
    2:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:30 AM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Cormar Bus
    18h 11m
    0
    11:59 PM
    Antofagasta
    Camus Bus Station
    6:10 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33

    Fastest Flights Friday

  • LAN Perú
    1h 52m
    0
    8:04 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:56 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $25
  • LAN Airlines
    1h 52m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:51 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $44
  • JetSmart
    1h 52m
    0
    3:52 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    5:44 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • Sky Airline
    1h 56m
    0
    9:23 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:19 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • JetSmart
    11h 15m
    0
    12:00 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:15 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $45
  • Fastest Buses Friday

  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37

    Fastest Buses Saturday

  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37

    Fastest Flights Sunday

  • LAN Airlines
    1h 52m
    0
    7:19 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:11 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $42
  • LAN Perú
    1h 52m
    0
    8:15 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:07 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $42
  • JetSmart
    1h 52m
    0
    7:18 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:10 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • LAN Airlines
    1h 52m
    0
    10:39 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:31 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $46
  • Sky Airline
    1h 56m
    0
    8:38 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:34 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • Fastest Buses Sunday

  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Cormar Bus
    18h 11m
    0
    11:59 PM
    Antofagasta
    Camus Bus Station
    6:10 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37

    Fastest Flights Monday

  • JetSmart
    1h 52m
    0
    11:51 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:43 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • JetSmart
    1h 52m
    0
    6:28 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    8:20 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $44
  • LAN Perú
    1h 52m
    0
    7:16 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:08 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $46
  • Sky Airline
    1h 56m
    0
    7:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:32 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • Sky Airline
    1h 56m
    0
    10:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:32 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $44
  • Fastest Buses Monday

  • Pullman San Andres
    17h 0m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    4:30 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • FlixBus
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    $31
  • Nueva Andimar Vip
    18h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $33
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Camus Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
Here you will find all operators and timetables for a Bus from Antofagasta to Santiago, RM

What are the most popular stations in Antofagasta and Santiago, RM?

In Antofagasta, you will usually depart from Camus Bus Station, Carlos Oviedo Cavada Bus Station or Maipú, while in Santiago, RM you will be arriving at Terminal San Borja, Sur Bus Station or Terminal Sur Bus Stop, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Santiago, RM from Antofagasta? With 9 connections between 9 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and Santiago, RM, you can pay as low as $24 with a Bus from Cikbus Elité.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from JetSmart: you will get to Santiago, RM in just 1h 52m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and Santiago, RM are JetSmart, FlixBus and Nueva Andimar Vip, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Antofagasta and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to Lo Prado, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Antofagasta to Santiago, RM?

The most popular companies between Antofagasta and Santiago, RM, are JetSmart, FlixBus and Nueva Andimar Vip. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus, Nueva Andimar Vip, Pluss Chile and 4 more.

Airlines: JetSmart, LAN Perú, Sky Airline and 1 more.

All you need to know when you travel from Antofagasta to Santiago, RM

Check all information on comfort and services on all modes of transports from Antofagasta to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Antofagasta to Santiago, RM

How can I reach Santiago, RM from Antofagasta?

Every day, there are on average 9 connections between Bus and Flight, with which you can get to Santiago, RM from Antofagasta.

How far is Santiago, RM from Antofagasta?

The distance between Antofagasta and Santiago, RM is 677.0 miles.

What is the most ecofriendly mode of transport between Antofagasta and Santiago, RM?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 29 kgs of CO2, a train 38 kgs, a car 185 kgs, and a flight 268 kgs.

What is the cheapest mode of transport from Antofagasta to Santiago, RM?

You can get to Santiago, RM with just $24 by taking a Bus from Cikbus Elité.

What is the fastest way to get from Antofagasta to Santiago, RM?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 1h 52m with a Flight from JetSmart.

More routes to Antofagasta and to Santiago, RM

Looking for more options? Here you can see the most popular routes to Antofagasta and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!

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