What is the best way to travel from Brussels to Prague?
Looking for a trip? Compare all the available Buses and Flights for the journey to Prague from Brussels. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Brussels?
You can get to Prague with just $46 by taking a Flight from Ryanair, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Ryanair1h 30m07:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport9:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/24/2025 7:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 9:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 30m
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Buzz19h 0m01:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport8:25 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/24/2025 1:25:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/25/2025 8:25:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 0m
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Brussels Airlines1h 25m09:00 PMBrussels AirportBrussels Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/24/2025 9:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 10:25:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 1h 25m
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Vueling Airlines9h 30m010:25 AMBrussels AirportBrussels Airport7:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/24/2025 10:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 7:55:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 9h 30m
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KLM Cityhopper5h 40m03:05 PMBrussels AirportBrussels Airport8:45 PMPrague AirportPrague Airport - T1/20EconomyA Flight from KLM Cityhopper goes from Brussels Airport, Brussels Airport (Belgium) at 4/24/2025 3:05:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 8:45:00 PM. 50 Economy ticket for $232 per person are available. Travel duration is 5h 40m
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FlixBus14h 40m04:15 PMBrusselsMidi Bus Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 4:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 6:55:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 1:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 0m
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FlixBus18h 35m04:15 PMBrusselsMidi Bus Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 4:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/25/2025 10:50:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 35m
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BlaBlaCar Bus20h 0m011:30 PMBrusselsMidi Bus Station7:30 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 7:30:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 20h 0m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/25/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/26/2025 1:10:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 15h 0m
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FlixBus13h 55m010:30 AMBrusselsNorth Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/25/2025 10:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/26/2025 12:25:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 55m
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/25/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/26/2025 12:05:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 35m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/25/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 10:55:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 19h 44m
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BlaBlaCar Bus19h 55m011:30 PMBrusselsMidi Bus Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/25/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/26/2025 7:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 55m
Cheapest Buses Friday
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/26/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/27/2025 12:05:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 13h 35m
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FlixBus18h 55m03:45 PMBrusselsHeysel10:40 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Heysel, Brussels (Belgium) at 4/26/2025 3:45:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/27/2025 10:40:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 55m
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FlixBus15h 15m09:25 PMBrusselsNorth Station12:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/26/2025 9:25:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/27/2025 12:40:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 15h 15m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/26/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/26/2025 10:55:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 44m
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Ryanair11h 45m07:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport6:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/26/2025 7:05:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 6:50:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 11h 45m
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Buzz9h 50m09:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport7:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/26/2025 9:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 7:20:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 9h 50m
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Wizz Air22h 40m08:40 AMBrussels South Charleroi AirportBrussels South Charleroi Airport7:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/26/2025 8:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 7:20:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 22h 40m
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British Airways12h 15m09:35 PMBrussels AirportBrussels Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from British Airways goes from Brussels Airport, Brussels Airport (Belgium) at 4/26/2025 9:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 9:50:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 12h 15m
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Iberia28h 35m07:05 AMBrussels AirportBrussels Airport11:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Iberia goes from Brussels Airport, Brussels Airport (Belgium) at 4/26/2025 7:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 11:40:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 28h 35m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Ryanair1h 30m06:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport7:55 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/27/2025 6:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 7:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 1h 30m
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AirBaltic1h 25m09:00 PMBrussels AirportBrussels Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from AirBaltic goes from Brussels Airport, Brussels Airport (Belgium) at 4/27/2025 9:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 10:25:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 1h 25m
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Buzz9h 15m09:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport7:05 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/27/2025 9:50:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 7:05:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 9h 15m
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SAS Scandinavian Airlines21h 35m09:20 PMBrussels AirportBrussels Airport6:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from SAS Scandinavian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/27/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 6:55:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 35m
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KLM Cityhopper5h 40m03:05 PMBrussels AirportBrussels Airport8:45 PMPrague AirportPrague Airport - T1/20EconomyA Flight from KLM Cityhopper goes from Brussels Airport, Brussels Airport (Belgium) at 4/27/2025 3:05:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 8:45:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 5h 40m
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RegioJet11h 50m06:30 PMBrusselsMidi Bus Station6:20 AMPragueWilsonova Bus Station0EconomyA Bus from RegioJet goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 6:30:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/28/2025 6:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 50m
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RegioJet11h 55m06:30 PMBrusselsMidi Bus Station6:25 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 6:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 6:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 55m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 1:10:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 15h 0m
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FlixBus15h 15m09:25 PMBrusselsNorth Station12:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/27/2025 9:25:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 12:40:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 15m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/27/2025 10:55:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 19h 44m
Cheapest Flights Sunday
Cheapest Buses Sunday
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FlixBus14h 40m04:15 PMBrusselsMidi Bus Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 4:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/29/2025 6:55:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/29/2025 1:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 15h 0m
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/28/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/29/2025 12:05:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 35m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 10:55:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 44m
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BlaBlaCar Bus19h 55m011:30 PMBrusselsMidi Bus Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/29/2025 7:25:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 19h 55m
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Ryanair1h 30m06:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport8:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 6:55:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 8:25:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 1h 30m
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Ryanair13h 15m06:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport7:35 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 6:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 7:35:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 13h 15m
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Ryanair6h 45m02:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport8:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 2:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 8:55:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 6h 45m
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Ryanair4h 30m02:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport6:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 2:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 6:40:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 30m
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Ryanair4h 45m08:05 AMBrussels South Charleroi AirportBrussels South Charleroi Airport12:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 8:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 12:50:00 PM. 50 Economy ticket for $303 per person are available. Travel duration is 4h 45m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus14h 40m04:15 PMBrusselsMidi Bus Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/29/2025 4:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/30/2025 6:55:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/29/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/30/2025 1:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 15h 0m
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FlixBus13h 55m010:30 AMBrusselsNorth Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/29/2025 10:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/30/2025 12:25:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 55m
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/29/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/30/2025 12:05:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 35m
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FlixBus18h 35m04:15 PMBrusselsMidi Bus Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/29/2025 4:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/30/2025 10:50:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 18h 35m
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Brussels Airlines1h 30m09:30 AMBrussels AirportBrussels Airport11:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 9:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 11:00:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 1h 30m
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EasyJet Airline4h 40m08:05 AMBrussels AirportBrussels Airport12:45 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 8:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 12:45:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 4h 40m
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Bringer Air Cargo Taxi Aereo6h 0m08:40 AMBrussels AirportBrussels Airport2:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 8:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 2:40:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 6h 0m
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Skyscanner4h 15m04:00 PMBrussels AirportBrussels Airport8:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 4:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 8:15:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 4h 15m
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KLM Cityhopper4h 20m06:10 AMBrussels AirportBrussels Airport10:30 AMPrague AirportPrague Airport - T1/20EconomyA Flight from KLM Cityhopper goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 6:10:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 10:30:00 AM. 50 Economy ticket for $233 per person are available. Travel duration is 4h 20m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/30/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 5/1/2025 12:05:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30 AMBrusselsNorth Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/30/2025 10:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 5/1/2025 12:25:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 55m
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FlixBus17h 55m03:15 AMBrusselsMidi Bus Station9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/30/2025 3:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/30/2025 9:10:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 55m
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FlixBus18h 15m03:15 AMBrusselsMidi Bus Station9:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/30/2025 3:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/30/2025 9:30:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 18h 15m
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FlixBus15h 55m07:00 AMBrusselsNorth Station10:55 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/30/2025 7:00:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/30/2025 10:55:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 55m
Cheapest Buses Wednesday
What are the fastest trips from Brussels to Prague?
You can get to Prague from Brussels in just 1h 25m with a Flight from Brussels Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Brussels Airlines1h 25m09:00 PMBrussels AirportBrussels Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/24/2025 9:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 10:25:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 1h 25m
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Ryanair1h 30m07:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport9:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/24/2025 7:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 9:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 30m
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KLM Cityhopper5h 40m03:05 PMBrussels AirportBrussels Airport8:45 PMPrague AirportPrague Airport - T1/20EconomyA Flight from KLM Cityhopper goes from Brussels Airport, Brussels Airport (Belgium) at 4/24/2025 3:05:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 8:45:00 PM. 50 Economy ticket for $232 per person are available. Travel duration is 5h 40m
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Vueling Airlines9h 30m010:25 AMBrussels AirportBrussels Airport7:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/24/2025 10:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/24/2025 7:55:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 9h 30m
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Buzz19h 0m01:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport8:25 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/24/2025 1:25:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/25/2025 8:25:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 0m
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FlixBus14h 40m04:15 PMBrusselsMidi Bus Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 4:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 6:55:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 1:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 0m
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FlixBus18h 35m04:15 PMBrusselsMidi Bus Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 4:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/25/2025 10:50:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 35m
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BlaBlaCar Bus20h 0m011:30 PMBrusselsMidi Bus Station7:30 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/24/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 7:30:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 20h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/25/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/26/2025 12:05:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30 AMBrusselsNorth Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/25/2025 10:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/26/2025 12:25:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 55m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/25/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/26/2025 1:10:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 15h 0m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/25/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/25/2025 10:55:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 19h 44m
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BlaBlaCar Bus19h 55m011:30 PMBrusselsMidi Bus Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/25/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/26/2025 7:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 55m
Fastest Buses Friday
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Buzz9h 50m09:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport7:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/26/2025 9:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 7:20:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 9h 50m
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Ryanair11h 45m07:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport6:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/26/2025 7:05:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 6:50:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 11h 45m
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British Airways12h 15m09:35 PMBrussels AirportBrussels Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from British Airways goes from Brussels Airport, Brussels Airport (Belgium) at 4/26/2025 9:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 9:50:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 12h 15m
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Wizz Air22h 40m08:40 AMBrussels South Charleroi AirportBrussels South Charleroi Airport7:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/26/2025 8:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 7:20:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 22h 40m
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Iberia28h 35m07:05 AMBrussels AirportBrussels Airport11:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Iberia goes from Brussels Airport, Brussels Airport (Belgium) at 4/26/2025 7:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 11:40:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 28h 35m
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/26/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/27/2025 12:05:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 13h 35m
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FlixBus15h 15m09:25 PMBrusselsNorth Station12:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/26/2025 9:25:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/27/2025 12:40:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 15h 15m
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FlixBus18h 55m03:45 PMBrusselsHeysel10:40 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Heysel, Brussels (Belgium) at 4/26/2025 3:45:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/27/2025 10:40:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 55m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/26/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/26/2025 10:55:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 44m
Fastest Flights Saturday
Fastest Buses Saturday
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AirBaltic1h 25m09:00 PMBrussels AirportBrussels Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from AirBaltic goes from Brussels Airport, Brussels Airport (Belgium) at 4/27/2025 9:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 10:25:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 1h 25m
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Ryanair1h 30m06:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport7:55 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/27/2025 6:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 7:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 1h 30m
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KLM Cityhopper5h 40m03:05 PMBrussels AirportBrussels Airport8:45 PMPrague AirportPrague Airport - T1/20EconomyA Flight from KLM Cityhopper goes from Brussels Airport, Brussels Airport (Belgium) at 4/27/2025 3:05:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/27/2025 8:45:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 5h 40m
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Buzz9h 15m09:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport7:05 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/27/2025 9:50:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 7:05:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 9h 15m
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SAS Scandinavian Airlines21h 35m09:20 PMBrussels AirportBrussels Airport6:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from SAS Scandinavian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/27/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 6:55:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 35m
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RegioJet11h 50m06:30 PMBrusselsMidi Bus Station6:20 AMPragueWilsonova Bus Station0EconomyA Bus from RegioJet goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 6:30:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/28/2025 6:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 50m
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RegioJet11h 55m06:30 PMBrusselsMidi Bus Station6:25 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 6:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 6:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 55m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 1:10:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 15h 0m
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FlixBus15h 15m09:25 PMBrusselsNorth Station12:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/27/2025 9:25:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 12:40:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 15m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/27/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/27/2025 10:55:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 19h 44m
Fastest Flights Sunday
Fastest Buses Sunday
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Ryanair1h 30m06:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport8:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 6:55:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 8:25:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 1h 30m
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Ryanair4h 30m02:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport6:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 2:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 6:40:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 30m
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Ryanair4h 45m08:05 AMBrussels South Charleroi AirportBrussels South Charleroi Airport12:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 8:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 12:50:00 PM. 50 Economy ticket for $303 per person are available. Travel duration is 4h 45m
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Ryanair6h 45m02:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport8:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 2:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 8:55:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 6h 45m
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Ryanair13h 15m06:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport7:35 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 4/28/2025 6:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/28/2025 7:35:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 13h 15m
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/28/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/29/2025 12:05:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 35m
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FlixBus14h 40m04:15 PMBrusselsMidi Bus Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 4:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/29/2025 6:55:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/29/2025 1:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 15h 0m
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BlaBlaCar Bus19h 44m03:11 AMBrusselsMidi Bus Station10:55 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 3:11:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/28/2025 10:55:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 44m
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BlaBlaCar Bus19h 55m011:30 PMBrusselsMidi Bus Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 4/28/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/29/2025 7:25:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 19h 55m
Fastest Flights Monday
Fastest Buses Monday
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Brussels Airlines1h 30m09:30 AMBrussels AirportBrussels Airport11:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 9:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 11:00:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 1h 30m
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Skyscanner4h 15m04:00 PMBrussels AirportBrussels Airport8:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 4:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 8:15:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 4h 15m
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KLM Cityhopper4h 20m06:10 AMBrussels AirportBrussels Airport10:30 AMPrague AirportPrague Airport - T1/20EconomyA Flight from KLM Cityhopper goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 6:10:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 10:30:00 AM. 50 Economy ticket for $233 per person are available. Travel duration is 4h 20m
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EasyJet Airline4h 40m08:05 AMBrussels AirportBrussels Airport12:45 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 8:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 12:45:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 4h 40m
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Bringer Air Cargo Taxi Aereo6h 0m08:40 AMBrussels AirportBrussels Airport2:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Brussels Airport, Brussels Airport (Belgium) at 4/29/2025 8:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 4/29/2025 2:40:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 6h 0m
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/29/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/30/2025 12:05:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30 AMBrusselsNorth Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/29/2025 10:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/30/2025 12:25:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 55m
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FlixBus14h 40m04:15 PMBrusselsMidi Bus Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/29/2025 4:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/30/2025 6:55:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m010:10 PMBrusselsMidi Bus Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/29/2025 10:10:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/30/2025 1:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 15h 0m
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FlixBus18h 35m04:15 PMBrusselsMidi Bus Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/29/2025 4:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 4/30/2025 10:50:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 18h 35m
Fastest Flights Tuesday
Fastest Buses Tuesday
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FlixBus13h 35m010:30 AMBrusselsNorth Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/30/2025 10:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 5/1/2025 12:05:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30 AMBrusselsNorth Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/30/2025 10:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 5/1/2025 12:25:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 55m
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FlixBus15h 55m07:00 AMBrusselsNorth Station10:55 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 4/30/2025 7:00:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/30/2025 10:55:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 55m
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FlixBus17h 55m03:15 AMBrusselsMidi Bus Station9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/30/2025 3:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 4/30/2025 9:10:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 55m
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FlixBus18h 15m03:15 AMBrusselsMidi Bus Station9:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 4/30/2025 3:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 4/30/2025 9:30:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 18h 15m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Brussels to Prague
What are the most popular stations in Brussels and Prague?
In Brussels, you will usually depart from Midi Bus Station, North Station or Gare Centrale, while in Prague you will be arriving at ÚAN Florenc, Train station Wilsonova or Wilsonova Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Brussels? With 8 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Brussels and Prague, you can pay as low as $46 with a Flight from Ryanair.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Brussels Airlines: you will get to Prague in just 1h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Brussels and Prague are FlixBus, Ryanair and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Brussels and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Saint-Gilles or to Horoměřice, and look at flights from Brussels South Charleroi Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Brussels to Prague?
The most popular companies between Brussels and Prague, are FlixBus, Ryanair and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, BlaBlaCar Bus and RegioJet
Airlines: Ryanair, Buzz, KLM Cityhopper and 10 more.
All you need to know when you travel from Brussels to Prague
Check all information on comfort and services on all modes of transports from Brussels to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Brussels to Prague
How can I reach Prague from Brussels?
Every day, there are on average 8 connections between Bus and Flight, with which you can get to Prague from Brussels.
How far is Prague from Brussels?
The distance between Brussels and Prague is 446.6 miles.
What is the most ecofriendly mode of transport between Brussels and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Brussels to Prague?
You can get to Prague with just $46 by taking a Flight from Ryanair.
What is the fastest way to get from Brussels to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 25m with a Flight from Brussels Airlines.
More routes to Brussels and to Prague
Looking for more options? Here you can see the most popular routes to Brussels and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Brussels
- Amsterdam to Brussels
- Basel to Brussels
- Berlin to Brussels
- Biarritz to Brussels
- Bordeaux to Brussels
- Bruges (BE) to Brussels
- Brussels South Charleroi Airport to Brussels
- Charleroi to Brussels
- Cologne/Bonn Airport to Brussels
- Geneva to Brussels
- Graz to Brussels
- Hamburg to Brussels
- Lille to Brussels
- Linz to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Madrid to Brussels
- Paris to Brussels
- Porto to Brussels
- San Sebastian to Brussels
- Vienna to Brussels
- Warsaw to Brussels
- Zurich to Brussels
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bern to Prague
- Brno to Prague
- Chomutov to Prague
- Cologne/Bonn Airport to Prague
- Dresden to Prague
- Dusseldorf to Prague
- Frankfurt am Main to Prague
- Humpolec to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- London to Prague
- Milan to Prague
- Most to Prague
- Munich to Prague
- Nuremberg to Prague
- Olomouc to Prague
- Pardubice to Prague
- Paris to Prague
- Pilsen to Prague
- Rome to Prague
- Vienna to Prague
- Zurich to Prague