How to get from La Serena to Antofagasta

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What is the best way to travel from La Serena to Antofagasta?

Looking for a trip? Compare all the available Buses and Flights for the journey to Antofagasta from La Serena. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 9 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
10h 30m
$24
$34
96
Flight
1h 20m
$43
$173
20

What is the cheapest way to reach Antofagasta from La Serena?

You can get to Antofagasta with just $24 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Saturday
from $28
Sunday
from $29
Monday
from $33
Tuesday
from $29
Wednesday
from $24
Thursday
from $33
Friday
from $24

    Cheapest Buses Saturday

  • Pluss Chile
    11h 35m
    0
    5:50 AM
    La Serena
    Central Bus Station
    5:25 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $28
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    11h 50m
    0
    5:30 AM
    La Serena
    El Sto, 1060
    5:20 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $38
  • Cheapest Flights Saturday

  • LAN Airlines
    1h 20m
    0
    11:07 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    12:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $49
  • JetSmart
    14h 41m
    0
    8:00 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    10:41 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $135
  • Sky Airline
    19h 12m
    0
    11:11 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    6:23 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $209
  • Sky Airline
    9h 24m
    0
    11:11 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:35 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $255
  • LAN Perú
    23h 47m
    0
    4:22 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    4:09 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $296

    Cheapest Buses Sunday

  • Cormar Bus
    11h 30m
    0
    6:40 PM
    La Serena
    Central Bus Station
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $29
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    13h 5m
    0
    3:30 AM
    La Serena
    El Sto, 1060
    4:35 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $38
  • Cheapest Flights Sunday

  • Sky Airline
    1h 25m
    0
    3:49 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    5:14 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $227
  • LAN Airlines
    1h 20m
    0
    8:28 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:48 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $232
  • JetSmart
    7h 50m
    0
    1:30 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:20 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $285
  • Sky Airline
    11h 27m
    0
    11:01 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    10:28 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $311
  • LAN Perú
    6h 29m
    0
    9:40 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    4:09 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $327

    Cheapest Buses Monday

  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Cikbus Elité
    11h 45m
    0
    5:15 AM
    La Serena
    Central Bus Station
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $38
  • Cormar Bus
    11h 0m
    0
    12:40 AM
    La Serena
    Central Bus Station
    11:40 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    First Class
    $39
  • Cheapest Flights Monday

  • JetSmart
    22h 25m
    0
    9:45 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $188
  • LAN Airlines
    1h 20m
    0
    11:00 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    12:20 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $196
  • Sky Airline
    1h 25m
    0
    7:31 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:56 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $198
  • JetSmart
    1h 20m
    0
    10:30 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    11:50 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $199
  • LAN Perú
    13h 14m
    0
    6:19 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    7:33 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $236

    Cheapest Buses Tuesday

  • Cormar Bus
    11h 30m
    0
    6:40 PM
    La Serena
    Central Bus Station
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $29
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Cikbus Elité
    11h 45m
    0
    5:15 AM
    La Serena
    Central Bus Station
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $38
  • Cheapest Flights Tuesday

  • JetSmart
    13h 1m
    0
    7:05 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:06 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $162
  • LAN Perú
    26h 21m
    0
    8:45 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    11:06 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $171
  • JetSmart
    14h 50m
    0
    5:16 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:06 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $188
  • LAN Perú
    26h 29m
    0
    8:45 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    11:14 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $189
  • LAN Airlines
    1h 20m
    0
    12:07 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    1:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $196

    Cheapest Buses Wednesday

  • FlixBus
    11h 35m
    0
    5:10 PM
    La Serena
    Central Bus Station
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $24
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    8:30 PM
    La Serena
    Central Bus Station
    8:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Cormar Bus
    11h 10m
    0
    3:30 PM
    La Serena
    Central Bus Station
    2:40 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    First Class
    $36
  • Cikbus Elité
    11h 45m
    0
    5:15 AM
    La Serena
    Central Bus Station
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $38

    Cheapest Buses Thursday

  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Cormar Bus
    10h 30m
    0
    7:45 PM
    La Serena
    Central Bus Station
    6:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cormar Bus
    First Class
    $38
  • Pullman Bus
    13h 5m
    0
    3:30 AM
    La Serena
    El Sto, 1060
    4:35 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $46
  • Cheapest Flights Thursday

  • LAN Airlines
    1h 20m
    0
    5:02 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    6:22 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $43
  • JetSmart
    1h 20m
    0
    8:30 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:50 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $46
  • Sky Airline
    7h 4m
    0
    2:11 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:15 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $122
  • JetSmart
    6h 11m
    0
    9:45 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    3:56 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $144
  • LAN Perú
    9h 52m
    0
    8:45 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    6:37 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $145

    Cheapest Buses Friday

  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $24
  • Cormar Bus
    11h 30m
    0
    6:40 PM
    La Serena
    Central Bus Station
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $28
  • FlixBus
    11h 35m
    0
    5:10 PM
    La Serena
    Central Bus Station
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    1:30 PM
    La Serena
    Central Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    13h 5m
    0
    3:30 AM
    La Serena
    El Sto, 1060
    4:35 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $46
  • Cheapest Flights Friday

  • JetSmart
    1h 20m
    0
    7:13 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:33 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $43
  • LAN Airlines
    1h 20m
    0
    3:25 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    4:45 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $44
  • Sky Airline
    11h 8m
    0
    9:40 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:48 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $111
  • Sky Airline
    12h 56m
    0
    7:52 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:48 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $121
  • LAN Airlines
    10h 40m
    0
    10:25 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:05 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $130

What are the fastest trips from La Serena to Antofagasta?

You can get to Antofagasta from La Serena in just 1h 20m with a Flight from LAN Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Saturday
from 1h 20m
Sunday
from 1h 20m
Monday
from 1h 20m
Tuesday
from 1h 20m
Wednesday
from 11h 10m
Thursday
from 1h 20m
Friday
from 1h 20m

    Fastest Flights Saturday

  • LAN Airlines
    1h 20m
    0
    11:07 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    12:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $49
  • Sky Airline
    9h 24m
    0
    11:11 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:35 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $255
  • JetSmart
    14h 41m
    0
    8:00 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    10:41 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $135
  • Sky Airline
    19h 12m
    0
    11:11 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    6:23 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $209
  • LAN Perú
    23h 47m
    0
    4:22 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    4:09 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $296
  • Fastest Buses Saturday

  • Pluss Chile
    11h 35m
    0
    5:50 AM
    La Serena
    Central Bus Station
    5:25 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $28
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman Bus
    11h 50m
    0
    5:30 AM
    La Serena
    El Sto, 1060
    5:20 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $38
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35

    Fastest Flights Sunday

  • LAN Airlines
    1h 20m
    0
    8:28 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:48 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $232
  • Sky Airline
    1h 25m
    0
    3:49 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    5:14 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $227
  • LAN Perú
    6h 29m
    0
    9:40 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    4:09 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $327
  • JetSmart
    7h 50m
    0
    1:30 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:20 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $285
  • Sky Airline
    11h 27m
    0
    11:01 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    10:28 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $311
  • Fastest Buses Sunday

  • Cormar Bus
    11h 30m
    0
    6:40 PM
    La Serena
    Central Bus Station
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $29
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    13h 5m
    0
    3:30 AM
    La Serena
    El Sto, 1060
    4:35 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $38

    Fastest Flights Monday

  • LAN Airlines
    1h 20m
    0
    11:00 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    12:20 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $196
  • JetSmart
    1h 20m
    0
    10:30 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    11:50 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $199
  • Sky Airline
    1h 25m
    0
    7:31 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:56 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $198
  • LAN Perú
    13h 14m
    0
    6:19 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    7:33 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $236
  • JetSmart
    22h 25m
    0
    9:45 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $188
  • Fastest Buses Monday

  • Cormar Bus
    11h 0m
    0
    12:40 AM
    La Serena
    Central Bus Station
    11:40 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    First Class
    $39
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Cikbus Elité
    11h 45m
    0
    5:15 AM
    La Serena
    Central Bus Station
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $38
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35

    Fastest Flights Tuesday

  • LAN Airlines
    1h 20m
    0
    12:07 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    1:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $196
  • JetSmart
    13h 1m
    0
    7:05 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:06 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $162
  • JetSmart
    14h 50m
    0
    5:16 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:06 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $188
  • LAN Perú
    26h 21m
    0
    8:45 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    11:06 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $171
  • LAN Perú
    26h 29m
    0
    8:45 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    11:14 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $189
  • Fastest Buses Tuesday

  • Cormar Bus
    11h 30m
    0
    6:40 PM
    La Serena
    Central Bus Station
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $29
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Cikbus Elité
    11h 45m
    0
    5:15 AM
    La Serena
    Central Bus Station
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $38
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35

    Fastest Buses Wednesday

  • Cormar Bus
    11h 10m
    0
    3:30 PM
    La Serena
    Central Bus Station
    2:40 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    First Class
    $36
  • FlixBus
    11h 35m
    0
    5:10 PM
    La Serena
    Central Bus Station
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $24
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Cikbus Elité
    11h 45m
    0
    5:15 AM
    La Serena
    Central Bus Station
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $38
  • Pullman San Andres
    12h 10m
    0
    8:30 PM
    La Serena
    Central Bus Station
    8:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35

    Fastest Flights Thursday

  • LAN Airlines
    1h 20m
    0
    5:02 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    6:22 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $43
  • JetSmart
    1h 20m
    0
    8:30 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:50 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $46
  • JetSmart
    6h 11m
    0
    9:45 AM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    3:56 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $144
  • Sky Airline
    7h 4m
    0
    2:11 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:15 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $122
  • LAN Perú
    9h 52m
    0
    8:45 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    6:37 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $145
  • Fastest Buses Thursday

  • Cormar Bus
    10h 30m
    0
    7:45 PM
    La Serena
    Central Bus Station
    6:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cormar Bus
    First Class
    $38
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    10:00 PM
    La Serena
    Central Bus Station
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    13h 5m
    0
    3:30 AM
    La Serena
    El Sto, 1060
    4:35 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $46

    Fastest Flights Friday

  • JetSmart
    1h 20m
    0
    7:13 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:33 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $43
  • LAN Airlines
    1h 20m
    0
    3:25 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    4:45 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $44
  • LAN Airlines
    10h 40m
    0
    10:25 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    9:05 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $130
  • Sky Airline
    11h 8m
    0
    9:40 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:48 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $111
  • Sky Airline
    12h 56m
    0
    7:52 PM
    La Florida, La Serena Airport
    La Florida, La Serena Airport
    8:48 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $121
  • Fastest Buses Friday

  • Cormar Bus
    11h 30m
    0
    6:40 PM
    La Serena
    Central Bus Station
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $28
  • Nueva Andimar Vip
    11h 35m
    0
    2:00 PM
    La Serena
    Central Bus Station
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $24
  • FlixBus
    11h 35m
    0
    5:10 PM
    La Serena
    Central Bus Station
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    12h 10m
    0
    1:30 PM
    La Serena
    Central Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    13h 5m
    0
    3:30 AM
    La Serena
    El Sto, 1060
    4:35 PM
    Antofagasta
    Camus Bus Station
    0
    Pullman Bus
    First Class
    $46
Here you will find all operators and timetables for a Bus from La Serena to Antofagasta

What are the most popular stations in La Serena and Antofagasta?

In La Serena, you will usually depart from Avda. Fco de Aguirre Station, Central Bus Station or El Sto, 1060, while in Antofagasta you will be arriving at Carlos Oviedo Cavada Bus Station, Camus Bus Station or Maipú, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Antofagasta from La Serena? With 9 connections between 9 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between La Serena and Antofagasta, you can pay as low as $24 with a Bus from FlixBus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Airlines: you will get to Antofagasta in just 1h 20m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting La Serena and Antofagasta are JetSmart, Sky Airline and Nueva Andimar Vip, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in La Serena and Antofagasta is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Florida, La Serena Airport or to La Negra, and look at flights from La Florida, La Serena Airport, and landing at Andrés Sabella Gálvez, Antofagasta Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from La Serena to Antofagasta?

The most popular companies between La Serena and Antofagasta, are JetSmart, Sky Airline and Nueva Andimar Vip. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Nueva Andimar Vip, FlixBus, Pullman San Andres and 4 more.

Airlines: JetSmart, Sky Airline, LAN Airlines and 1 more.

All you need to know when you travel from La Serena to Antofagasta

Check all information on comfort and services on all modes of transports from La Serena to Antofagasta. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from La Serena to Antofagasta

How can I reach Antofagasta from La Serena?

Every day, there are on average 9 connections between Bus and Flight, with which you can get to Antofagasta from La Serena.

How far is Antofagasta from La Serena?

The distance between La Serena and Antofagasta is 435.4 miles.

What is the most ecofriendly mode of transport between La Serena and Antofagasta?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 119 kgs, and a flight 172 kgs.

What is the cheapest mode of transport from La Serena to Antofagasta?

You can get to Antofagasta with just $24 by taking a Bus from FlixBus.

What is the fastest way to get from La Serena to Antofagasta?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Antofagasta in just 1h 20m with a Flight from LAN Airlines.

More routes to La Serena and to Antofagasta

Looking for more options? Here you can see the most popular routes to La Serena and to Antofagasta. Simply click on a connection, and you’ll find all the details about the route!

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