What is the best way to travel from Lyon to Rome?
Looking for a trip? Compare all the available Buses, Carpool and Flights for the journey to Rome from Lyon. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Lyon?
You can get to Rome with just $40 by taking a Bus from Itabus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/8/2025 7:00:00 AM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/8/2025 7:00:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 30m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/7/2025 11:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 30m
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FlixBus15h 40m08:05 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 8:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/7/2025 11:45:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 15h 40m
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BlaBlaCar10h 20m05:00 AMLyon3:20 PMRome0EconomyA Car from BlaBlaCar goes from , Lyon (France) at 5/7/2025 5:00:00 AM to , Rome (Italy) arriving at 5/7/2025 3:20:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 10h 20m
Cheapest Buses Wednesday
Cheapest Carpool Wednesday
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/8/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/8/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/9/2025 12:15:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 15h 30m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/8/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 4:05:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 16h 6m
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LC Perú24h 25m09:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 9:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 10:15:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 24h 25m
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Vueling Airlines10h 5m010:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 10:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 8:20:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 10h 5m
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LC Perú12h 15m09:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 9:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 5/9/2025 10:05:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 12h 15m
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EasyJet Airline17h 55m04:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:10 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 4:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 10:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 17h 55m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/9/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 11:45:00 PM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 14h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/9/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 11:45:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 10m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/9/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/10/2025 12:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 15h 30m
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LC Perú24h 25m09:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 9:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/10/2025 10:15:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 24h 25m
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EasyJet Airline1h 35m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:35 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 7:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 8:35:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 35m
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Vueling Airlines13h 40m06:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 6:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/10/2025 8:20:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 13h 40m
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Volotea6h 0m07:45 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:45 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 7:45:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 1:45:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 6h 0m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/10/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/10/2025 11:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 10m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/11/2025 12:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 15h 30m
Cheapest Buses Saturday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 11:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 4:05:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/12/2025 12:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 30m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 11:45:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 14h 30m
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LC Perú24h 20m08:40 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:00 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 8:40:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/12/2025 9:00:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 24h 20m
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EasyJet Airline1h 25m07:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 7:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/11/2025 9:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 1h 25m
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LC Perú11h 40m09:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:30 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 9:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 5/12/2025 9:30:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 11h 40m
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Volotea4h 55m011:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 11:30:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/11/2025 4:25:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 4h 55m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/12/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/13/2025 12:15:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/12/2025 11:45:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 14h 10m
Cheapest Buses Monday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/14/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 11:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 4:05:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 50m
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EasyJet Airline1h 25m07:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:50 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 7:25:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/13/2025 8:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 1h 25m
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Volotea17h 5m08:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:35 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 8:30:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/14/2025 1:35:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 5m
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Vueling Airlines4h 40m09:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/13/2025 2:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 4h 40m
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Tunisair23h 10m011:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Tunisair goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 11:05:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/14/2025 10:15:00 AM. 50 Economy ticket for $207 per person are available. Travel duration is 23h 10m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
What are the fastest trips from Lyon to Rome?
You can get to Rome from Lyon in just 1h 25m with a Flight from EasyJet Airline. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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BlaBlaCar10h 20m05:00 AMLyon3:20 PMRome0EconomyA Car from BlaBlaCar goes from , Lyon (France) at 5/7/2025 5:00:00 AM to , Rome (Italy) arriving at 5/7/2025 3:20:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 10h 20m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/7/2025 11:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/8/2025 7:00:00 AM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/8/2025 7:00:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 30m
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FlixBus15h 40m08:05 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/7/2025 8:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/7/2025 11:45:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 15h 40m
Fastest Carpool Wednesday
Fastest Buses Wednesday
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Vueling Airlines10h 5m010:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 10:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 8:20:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 10h 5m
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LC Perú12h 15m09:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 9:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 5/9/2025 10:05:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 12h 15m
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EasyJet Airline17h 55m04:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:10 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 4:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 10:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 17h 55m
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Air Malta20h 30m011:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/8/2025 11:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 8:10:00 PM. 50 Economy ticket for $201 per person are available. Travel duration is 20h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/8/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/8/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/9/2025 12:15:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 15h 30m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/8/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 4:05:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 16h 6m
Fastest Flights Thursday
Fastest Buses Thursday
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EasyJet Airline1h 35m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:35 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 7:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 8:35:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 35m
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Volotea6h 0m07:45 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:45 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 7:45:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/9/2025 1:45:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 6h 0m
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Vueling Airlines13h 40m06:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 6:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/10/2025 8:20:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 13h 40m
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Tunisair22h 0m05:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station3:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Tunisair goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/9/2025 5:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/10/2025 3:05:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 22h 0m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/9/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 11:45:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/9/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/9/2025 11:45:00 PM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 14h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/9/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/10/2025 12:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 15h 30m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/10/2025 11:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/10/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/10/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/11/2025 12:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 15h 30m
Fastest Buses Saturday
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EasyJet Airline1h 25m07:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 7:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/11/2025 9:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 1h 25m
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Volotea4h 55m011:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 11:30:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/11/2025 4:25:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 4h 55m
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LC Perú11h 40m09:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:30 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 9:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 5/12/2025 9:30:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 11h 40m
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Vueling Airlines14h 15m06:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/11/2025 6:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/12/2025 8:20:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 14h 15m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 11:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 11:45:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/11/2025 4:05:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/11/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/12/2025 12:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 30m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/12/2025 11:45:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/12/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/12/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/13/2025 12:15:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 15h 30m
Fastest Buses Monday
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EasyJet Airline1h 25m07:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:50 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 7:25:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/13/2025 8:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 1h 25m
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Vueling Airlines4h 40m09:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/13/2025 2:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 4h 40m
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KLM Cityhopper8h 40m02:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:45 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from KLM Cityhopper goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 2:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/13/2025 10:45:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 8h 40m
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Volotea17h 5m08:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:35 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 5/13/2025 8:30:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 5/14/2025 1:35:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 5m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 11:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/13/2025 4:05:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 50m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 5/13/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/14/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
Fastest Flights Tuesday
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Lyon to Rome
What are the most popular stations in Lyon and Rome?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Rome you will be arriving at Tiburtina Bus Station, Anagnina Bus Station or Termini Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Lyon? With 8 connections between 4 Bus, Carpool and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Rome, you can pay as low as $40 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Rome in just 1h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Rome are Itabus, FlixBus and LC Perú, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Settebagni, and look at flights from Lyons St. Exupery Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Rome?
The most popular companies between Lyon and Rome, are Itabus, FlixBus and LC Perú. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Airlines: LC Perú, Vueling Airlines, EasyJet Airline and 5 more.
All you need to know when you travel from Lyon to Rome
Check all information on comfort and services on all modes of transports from Lyon to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Rome
How can I reach Rome from Lyon?
Every day, there are on average 8 connections between Bus, Carpool and Flight, with which you can get to Rome from Lyon.
How far is Rome from Lyon?
The distance between Lyon and Rome is 465.5 miles.
What is the most ecofriendly mode of transport between Lyon and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Lyon to Rome?
You can get to Rome with just $40 by taking a Bus from Itabus.
What is the fastest way to get from Lyon to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 25m with a Flight from EasyJet Airline.
More routes to Lyon and to Rome
Looking for more options? Here you can see the most popular routes to Lyon and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Ambérieu-en-Bugey to Lyon
- Barcelona to Lyon
- Bergamo to Lyon
- Biarritz to Lyon
- Bordeaux to Lyon
- Brive-la-Gaillarde to Lyon
- Brussels to Lyon
- Frankfurt am Main to Lyon
- Geneva to Lyon
- Lille to Lyon
- London to Lyon
- Madrid to Lyon
- Marseille to Lyon
- Metz to Lyon
- Milan to Lyon
- Nantes to Lyon
- Paris to Lyon
- Porto to Lyon
- Rome to Lyon
- Saint-Étienne to Lyon
- Strasbourg to Lyon
- Toulon to Lyon
- Toulouse to Lyon
- Trips to Rome
- Battipaglia to Rome
- Catania to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitavecchia to Rome
- Fisciano to Rome
- Frascineto to Rome
- Grottaminarda to Rome
- Isernia to Rome
- L'Aquila to Rome
- Licata to Rome
- Messina to Rome
- Milan to Rome
- Milazzo to Rome
- Naples to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Porto San Giorgio to Rome
- Rome Ciampino Airport to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- San Benedetto del Tronto to Rome
- Vibo Valentia to Rome
- Villa Rosa to Rome