What is the best way to travel from Prague to Brussels?
Looking for a trip? Compare all the available Buses, Flights and Carpool for the journey to Brussels from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Prague?
You can get to Brussels with just $35 by taking a Flight from Ryanair, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/27/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2025 7:20:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 15h 5m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/27/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2025 1:55:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 14h 50m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/27/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 3/27/2025 6:05:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/27/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 3/27/2025 6:05:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 13h 55m
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Transavia Airlines25h 25m09:00 AMPrague AirportPrague Airport - T1/210:25 AMAntwerp AirportAntwerp Airport0EconomyA Flight from Transavia Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 9:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/28/2025 10:25:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 25h 25m
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Buzz13h 55m06:00 AMPrague AirportPrague Airport - T1/27:55 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/27/2025 7:55:00 PM. 50 Economy ticket for $379 per person are available. Travel duration is 13h 55m
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British Airways27h 50m06:35 AMPrague AirportPrague Airport - T1/210:25 AMAntwerp AirportAntwerp Airport0EconomyA Flight from British Airways goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 6:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/28/2025 10:25:00 AM. 50 Economy ticket for $403 per person are available. Travel duration is 27h 50m
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Brussels Airlines27h 35m06:50 AMPrague AirportPrague Airport - T1/210:25 AMAntwerp AirportAntwerp Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 6:50:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/28/2025 10:25:00 AM. 50 Economy ticket for $445 per person are available. Travel duration is 27h 35m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/28/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/29/2025 7:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 15h 5m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/28/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/29/2025 1:55:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 50m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/28/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 3/28/2025 6:05:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/28/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 3/28/2025 6:05:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 55m
Cheapest Buses Friday
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FlixBus16h 5m04:15 PMPragueÚAN Florenc8:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2025 8:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 16h 5m
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FlixBus15h 50m011:05 PMPragueÚAN Florenc2:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2025 2:55:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 15h 50m
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FlixBus16h 55m05:30 PMPragueWilsonova Bus Station10:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/29/2025 5:30:00 PM to North Station, Brussels (Belgium) arriving at 3/30/2025 10:25:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 55m
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FlixBus19h 40m04:45 PMPragueWilsonova Bus Station12:25 PMBrusselsHeysel0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/29/2025 4:45:00 PM to Heysel, Brussels (Belgium) arriving at 3/30/2025 12:25:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 19h 40m
Cheapest Buses Saturday
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FlixBus14h 15m04:50 AMPragueWilsonova Bus Station7:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/30/2025 4:50:00 AM to North Station, Brussels (Belgium) arriving at 3/30/2025 7:05:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m05:10 AMPragueNa Knížecí Station7:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/30/2025 5:10:00 AM to North Station, Brussels (Belgium) arriving at 3/30/2025 7:05:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 13h 55m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/31/2025 1:55:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 14h 50m
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FlixBus18h 15m011:50 PMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/30/2025 11:50:00 PM to North Station, Brussels (Belgium) arriving at 3/31/2025 6:05:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 15m
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Ryanair43h 15m06:55 PMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 6:55:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $235 per person are available. Travel duration is 43h 15m
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Buzz31h 15m06:05 AMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 6:05:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $278 per person are available. Travel duration is 31h 15m
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Bringer Air Cargo Taxi Aereo20h 0m05:20 PMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 5:20:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $325 per person are available. Travel duration is 20h 0m
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Norwegian Air International29h 0m08:20 AMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Norwegian Air International goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 8:20:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $351 per person are available. Travel duration is 29h 0m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 3/31/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/31/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 3/31/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/31/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/1/2025 7:20:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 15h 5m
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FlixBus17h 45m02:45 PMPragueWilsonova Bus Station8:30 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2025 2:45:00 PM to North Station, Brussels (Belgium) arriving at 4/1/2025 8:30:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 17h 45m
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Smartwings20h 50m05:20 PMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 5:20:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 50m
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Buzz31h 35m06:35 AMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 6:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 31h 35m
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LC Perú29h 45m08:25 AMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 8:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 29h 45m
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Ryanair27h 45m010:25 AMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 10:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 27h 45m
Cheapest Buses Monday
Cheapest Flights Monday
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Ryanair1h 30m08:55 AMPrague AirportPrague Airport - T1/210:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 8:55:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/1/2025 10:25:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 1h 30m
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Vueling Airlines13h 5m08:40 PMPrague AirportPrague Airport - T1/29:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 8:40:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/2/2025 9:45:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 13h 5m
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Ryanair7h 50m09:05 AMPrague AirportPrague Airport - T1/24:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 9:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/1/2025 4:55:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 7h 50m
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LC Perú10h 40m09:20 AMPrague AirportPrague Airport - T1/28:00 PMBrussels AirportBrussels Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 9:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/1/2025 8:00:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 10h 40m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 4/1/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 4/1/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 4/1/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 4/1/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 55m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/2/2025 7:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 20h 0m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/1/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/2/2025 7:20:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 15h 5m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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Ryanair1h 30m09:15 AMPrague AirportPrague Airport - T1/210:45 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 9:15:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/2/2025 10:45:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 30m
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Buzz1h 30m02:20 PMPrague AirportPrague Airport - T1/23:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 2:20:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/2/2025 3:50:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 1h 30m
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Vueling Airlines13h 0m08:45 PMPrague AirportPrague Airport - T1/29:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 8:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/3/2025 9:45:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 0m
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LC Perú8h 40m08:25 AMPrague AirportPrague Airport - T1/25:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 8:25:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/2/2025 5:05:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 40m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/2/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 7:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 15h 5m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 7:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 20h 0m
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FlixBus22h 40m011:20 AMPrague AirportPrague Airport - T1/210:00 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 10:00:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 22h 40m
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FlixBus19h 0m08:50 AMPrague AirportPrague Airport - T1/23:50 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 3:50:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 19h 0m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
What are the fastest trips from Prague to Brussels?
You can get to Brussels from Prague in just 1h 30m with a Flight from Ryanair. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/27/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 3/27/2025 6:05:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/27/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 3/27/2025 6:05:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 14h 15m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/27/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2025 1:55:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 14h 50m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/27/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2025 7:20:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 15h 5m
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Buzz13h 55m06:00 AMPrague AirportPrague Airport - T1/27:55 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/27/2025 7:55:00 PM. 50 Economy ticket for $379 per person are available. Travel duration is 13h 55m
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EasyJet Airline22h 55m011:30 AMPrague AirportPrague Airport - T1/210:25 AMAntwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 11:30:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/28/2025 10:25:00 AM. 50 Economy ticket for $468 per person are available. Travel duration is 22h 55m
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Transavia Airlines25h 25m09:00 AMPrague AirportPrague Airport - T1/210:25 AMAntwerp AirportAntwerp Airport0EconomyA Flight from Transavia Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 9:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/28/2025 10:25:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 25h 25m
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Brussels Airlines27h 35m06:50 AMPrague AirportPrague Airport - T1/210:25 AMAntwerp AirportAntwerp Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2025 6:50:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/28/2025 10:25:00 AM. 50 Economy ticket for $445 per person are available. Travel duration is 27h 35m
Fastest Buses Thursday
Fastest Flights Thursday
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/28/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 3/28/2025 6:05:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/28/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 3/28/2025 6:05:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 14h 15m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/28/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/29/2025 1:55:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 50m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/28/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/29/2025 7:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 15h 5m
Fastest Buses Friday
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FlixBus15h 50m011:05 PMPragueÚAN Florenc2:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2025 2:55:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 15h 50m
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FlixBus16h 5m04:15 PMPragueÚAN Florenc8:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2025 8:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 16h 5m
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FlixBus16h 55m05:30 PMPragueWilsonova Bus Station10:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/29/2025 5:30:00 PM to North Station, Brussels (Belgium) arriving at 3/30/2025 10:25:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 55m
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FlixBus18h 25m06:00 PMPragueÚAN Florenc12:25 PMBrusselsHeysel0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2025 6:00:00 PM to Heysel, Brussels (Belgium) arriving at 3/30/2025 12:25:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 18h 25m
Fastest Buses Saturday
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FlixBus13h 55m05:10 AMPragueNa Knížecí Station7:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/30/2025 5:10:00 AM to North Station, Brussels (Belgium) arriving at 3/30/2025 7:05:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m04:50 AMPragueWilsonova Bus Station7:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/30/2025 4:50:00 AM to North Station, Brussels (Belgium) arriving at 3/30/2025 7:05:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 15m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/31/2025 1:55:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 14h 50m
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FlixBus15h 15m011:05 PMPragueÚAN Florenc2:20 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2025 11:05:00 PM to North Station, Brussels (Belgium) arriving at 3/31/2025 2:20:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 15m
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Smartwings19h 15m06:05 PMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 6:05:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $355 per person are available. Travel duration is 19h 15m
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Bringer Air Cargo Taxi Aereo20h 0m05:20 PMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 5:20:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $325 per person are available. Travel duration is 20h 0m
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Norwegian Air International29h 0m08:20 AMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Norwegian Air International goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 8:20:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $351 per person are available. Travel duration is 29h 0m
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Buzz31h 15m06:05 AMPrague AirportPrague Airport - T1/21:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/30/2025 6:05:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/31/2025 1:20:00 PM. 50 Economy ticket for $278 per person are available. Travel duration is 31h 15m
Fastest Buses Sunday
Fastest Flights Sunday
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/31/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 3/31/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 3/31/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/31/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/1/2025 7:20:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 15h 5m
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FlixBus15h 25m06:00 PMPragueÚAN Florenc9:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/31/2025 6:00:00 PM to North Station, Brussels (Belgium) arriving at 4/1/2025 9:25:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 25m
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Smartwings20h 50m05:20 PMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 5:20:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 50m
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Ryanair27h 45m010:25 AMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 10:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 27h 45m
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Air Bagan28h 30m09:40 AMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 9:40:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 28h 30m
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LC Perú29h 45m08:25 AMPrague AirportPrague Airport - T1/22:10 PMAntwerp AirportAntwerp Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/31/2025 8:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 4/1/2025 2:10:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 29h 45m
Fastest Buses Monday
Fastest Flights Monday
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Ryanair1h 30m08:55 AMPrague AirportPrague Airport - T1/210:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 8:55:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/1/2025 10:25:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 1h 30m
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Brussels Airlines1h 30m011:50 AMPrague AirportPrague Airport - T1/21:20 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 11:50:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/1/2025 1:20:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 1h 30m
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KLM - Royal Dutch Airlines3h 40m06:00 AMPrague AirportPrague Airport - T1/29:40 AMBrussels AirportBrussels Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/1/2025 9:40:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 3h 40m
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Skyscanner5h 10m012:50 PMPrague AirportPrague Airport - T1/26:00 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 12:50:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/1/2025 6:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 5h 10m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 4/1/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 4/1/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 4/1/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 4/1/2025 6:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/1/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/2/2025 7:20:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 15h 5m
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FlixBus19h 0m08:50 AMPrague AirportPrague Airport - T1/23:50 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/2/2025 3:50:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 19h 0m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Ryanair1h 30m09:15 AMPrague AirportPrague Airport - T1/210:45 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 9:15:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/2/2025 10:45:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 30m
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Buzz1h 30m02:20 PMPrague AirportPrague Airport - T1/23:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 2:20:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 4/2/2025 3:50:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 1h 30m
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Brussels Airlines1h 30m011:50 AMPrague AirportPrague Airport - T1/21:20 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 11:50:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/2/2025 1:20:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 1h 30m
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KLM - Royal Dutch Airlines3h 40m06:00 AMPrague AirportPrague Airport - T1/29:40 AMBrussels AirportBrussels Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 4/2/2025 9:40:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 3h 40m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/2/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 7:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 15h 5m
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FlixBus18h 40m06:50 PMPrague AirportPrague Airport - T1/21:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 6:50:00 PM to North Station, Brussels (Belgium) arriving at 4/3/2025 1:30:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 18h 40m
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FlixBus19h 0m08:50 AMPrague AirportPrague Airport - T1/23:50 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 3:50:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 19h 0m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/2/2025 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/3/2025 7:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 20h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Prague to Brussels
What are the most popular stations in Prague and Brussels?
In Prague, you will usually depart from ÚAN Florenc, Wilsonova Bus Station or Train station Wilsonova, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Prague? With 10 connections between 1 Bus, Flight and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Brussels, you can pay as low as $35 with a Flight from Ryanair.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Brussels in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Brussels are FlixBus, Ryanair and Buzz, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Saint-Gilles, and look at flights from Prague Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Brussels?
The most popular companies between Prague and Brussels, are FlixBus, Ryanair and Buzz. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Ryanair, Buzz, LC Perú and 13 more.
All you need to know when you travel from Prague to Brussels
Check all information on comfort and services on all modes of transports from Prague to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Brussels
How can I reach Brussels from Prague?
Every day, there are on average 10 connections between Bus, Flight and Carpool, with which you can get to Brussels from Prague.
How far is Brussels from Prague?
The distance between Prague and Brussels is 446.6 miles.
What is the most ecofriendly mode of transport between Prague and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Prague to Brussels?
You can get to Brussels with just $35 by taking a Flight from Ryanair.
What is the fastest way to get from Prague to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 30m with a Flight from Ryanair.
More routes to Prague and to Brussels
Looking for more options? Here you can see the most popular routes to Prague and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Cologne to Prague
- Dresden to Prague
- Dusseldorf to Prague
- Frankfurt am Main to Prague
- Hradec Kralove to Prague
- Humpolec to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- London to Prague
- Milan to Prague
- Most to Prague
- Munich to Prague
- Nuremberg to Prague
- Olomouc to Prague
- Paris to Prague
- Pilsen to Prague
- Prague Airport to Prague
- Rome to Prague
- Salzburg to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Brussels
- Aachen to Brussels
- Arnheim to Brussels
- Basel to Brussels
- Bordeaux to Brussels
- Brive-la-Gaillarde to Brussels
- Bruges (BE) to Brussels
- Charleroi to Brussels
- Dusseldorf to Brussels
- Fribourg im Uechtland to Brussels
- Geneva to Brussels
- Hamburg to Brussels
- Leeds to Brussels
- Liege to Brussels
- Lille to Brussels
- Lugano to Brussels
- Milan to Brussels
- Munich to Brussels
- Nancy to Brussels
- Nantes to Brussels
- Nice to Brussels
- Paris Charles de Gaulle Airport to Brussels
- Paris Orly Airport to Brussels
- Valencia to Brussels
- Vienna to Brussels