What is the best way to travel from Rome to Brno?
Looking for a trip? Compare all the available Buses and Flights for the journey to Brno from Rome. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brno from Rome?
You can get to Brno with just $63 by taking a Bus from RegioJet, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/5/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 5:45:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 24h 45m
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FlixBus24h 35m01:05 PMRomeAnagnina Bus Station1:40 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/5/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 1:40:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 24h 35m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/5/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 8:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 40m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/5/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 8:00:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 20h 55m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/5/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 8:25:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 5m
Cheapest Buses Monday
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FlixBus24h 55m07:30 AMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/6/2025 7:30:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 5/7/2025 8:25:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 55m
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FlixBus23h 35m08:50 AMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/6/2025 8:50:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 5/7/2025 8:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 23h 35m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/6/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/7/2025 8:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 20h 55m
Cheapest Buses Tuesday
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/7/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 5:45:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 24h 45m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/7/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 5:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 24h 20m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/7/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 8:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 55m
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FlixBus23h 35m08:50 AMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/7/2025 8:50:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 8:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 23h 35m
Cheapest Buses Wednesday
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Ryanair9h 15m06:00 AMRome Ciampino AirportRome Ciampino Airport3:15 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 5/8/2025 6:00:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 3:15:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 15m
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Siam Air Transport1h 40m011:00 AMRome Fiumicino AirportRome Fiumicino Airport12:40 PMBrno AirportBrno Airport0EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 11:00:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 12:40:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 1h 40m
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Skyscanner46h 50m01:40 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 1:40:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 46h 50m
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South African Express Airways1h 40m011:00 AMRome Fiumicino AirportRome Fiumicino Airport12:40 PMBrno AirportBrno Airport0EconomyA Flight from South African Express Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 11:00:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 12:40:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 40m
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LC Perú8h 35m06:40 AMRome Fiumicino AirportRome Fiumicino Airport3:15 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 6:40:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 3:15:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 8h 35m
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FlixBus24h 35m01:05 PMRomeAnagnina Bus Station1:40 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/8/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 1:40:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 24h 35m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/8/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 8:25:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/8/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 8:25:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 5m
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/8/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 5:45:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 24h 45m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/8/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 5:45:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 24h 20m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/9/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 5:45:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 45m
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FlixBus24h 15m01:05 PMRomeAnagnina Bus Station1:20 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/9/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 1:20:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 24h 15m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/9/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 8:25:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/9/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 8:25:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/9/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 8:00:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 20h 55m
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Siam Air Transport27h 0m09:30 AMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 9:30:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 0m
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Siam Air Transport15h 20m09:10 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 9:10:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 15h 20m
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ITA Airways14h 30m010:00 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 10:00:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 14h 30m
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ITA Airways22h 30m02:00 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 2:00:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 22h 30m
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Ryanair27h 25m07:50 PMRome Ciampino AirportRome Ciampino Airport11:15 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 5/9/2025 7:50:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 11:15:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 27h 25m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus24h 15m01:05 PMRomeAnagnina Bus Station1:20 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/10/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 1:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 24h 15m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/10/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 8:25:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/10/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 8:25:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/10/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 8:00:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 20h 55m
Cheapest Buses Saturday
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RegioJet17h 40m01:00 PMRomeTiburtina Bus Station6:40 AMBrnoBenesova Bus Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 5/11/2025 1:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 5/12/2025 6:40:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 40m
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FlixBus24h 35m01:05 PMRomeAnagnina Bus Station1:40 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/11/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/12/2025 1:40:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 35m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/11/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/12/2025 5:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 20m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/11/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/12/2025 8:00:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 20h 55m
Cheapest Buses Sunday
What are the fastest trips from Rome to Brno?
You can get to Brno from Rome in just 1h 40m with a Flight from Siam Air Transport. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/5/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 8:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/5/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 8:25:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/5/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 8:00:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 20h 55m
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FlixBus24h 35m01:05 PMRomeAnagnina Bus Station1:40 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/5/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 1:40:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 24h 35m
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/5/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/6/2025 5:45:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 24h 45m
Fastest Buses Monday
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/6/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/7/2025 8:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 20h 55m
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FlixBus23h 35m08:50 AMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/6/2025 8:50:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 5/7/2025 8:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 23h 35m
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FlixBus24h 55m07:30 AMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/6/2025 7:30:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 5/7/2025 8:25:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 55m
Fastest Buses Tuesday
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/7/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 8:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 55m
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FlixBus23h 35m08:50 AMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/7/2025 8:50:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 8:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 23h 35m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/7/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 5:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 24h 20m
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/7/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/8/2025 5:45:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 24h 45m
Fastest Buses Wednesday
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Siam Air Transport1h 40m011:00 AMRome Fiumicino AirportRome Fiumicino Airport12:40 PMBrno AirportBrno Airport0EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 11:00:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 12:40:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 1h 40m
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South African Express Airways1h 40m011:00 AMRome Fiumicino AirportRome Fiumicino Airport12:40 PMBrno AirportBrno Airport0EconomyA Flight from South African Express Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 11:00:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 12:40:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 40m
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LC Perú8h 35m06:40 AMRome Fiumicino AirportRome Fiumicino Airport3:15 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 6:40:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 3:15:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 8h 35m
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Ryanair9h 15m06:00 AMRome Ciampino AirportRome Ciampino Airport3:15 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 5/8/2025 6:00:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/8/2025 3:15:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 15m
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Skyscanner46h 50m01:40 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/8/2025 1:40:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 46h 50m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/8/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 8:25:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/8/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 8:25:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 5m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/8/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 5:45:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 24h 20m
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FlixBus24h 35m01:05 PMRomeAnagnina Bus Station1:40 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/8/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 1:40:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 24h 35m
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/8/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/9/2025 5:45:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 24h 45m
Fastest Flights Thursday
Fastest Buses Thursday
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ITA Airways14h 30m010:00 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 10:00:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 14h 30m
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Siam Air Transport15h 20m09:10 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 9:10:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 15h 20m
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ITA Airways22h 30m02:00 PMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 2:00:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 22h 30m
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Siam Air Transport27h 0m09:30 AMRome Fiumicino AirportRome Fiumicino Airport12:30 PMBrno AirportBrno Airport0EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 5/9/2025 9:30:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 12:30:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 0m
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Ryanair27h 25m07:50 PMRome Ciampino AirportRome Ciampino Airport11:15 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 5/9/2025 7:50:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 5/10/2025 11:15:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 27h 25m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/9/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 8:25:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/9/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 8:25:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/9/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 8:00:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 20h 55m
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FlixBus24h 15m01:05 PMRomeAnagnina Bus Station1:20 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/9/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 1:20:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 24h 15m
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FlixBus24h 45m05:00 PMRomeTiburtina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/9/2025 5:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/10/2025 5:45:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 45m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/10/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 8:25:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/10/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 8:25:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/10/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 8:00:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 20h 55m
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FlixBus24h 15m01:05 PMRomeAnagnina Bus Station1:20 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/10/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/11/2025 1:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 24h 15m
Fastest Buses Saturday
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RegioJet17h 40m01:00 PMRomeTiburtina Bus Station6:40 AMBrnoBenesova Bus Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 5/11/2025 1:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 5/12/2025 6:40:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 40m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/11/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/12/2025 8:00:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 20h 55m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/11/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/12/2025 5:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 20m
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FlixBus24h 35m01:05 PMRomeAnagnina Bus Station1:40 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 5/11/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 5/12/2025 1:40:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 35m
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Rome to Brno
What are the most popular stations in Rome and Brno?
In Rome, you will usually depart from Tiburtina Bus Station, Anagnina Bus Station or Termini Central Station, while in Brno you will be arriving at Hotel Grand, Train station or Starý Čermákova Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brno from Rome? With 5 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Brno, you can pay as low as $63 with a Bus from RegioJet.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Siam Air Transport: you will get to Brno in just 1h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Brno are FlixBus, Siam Air Transport and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Brno is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Moravany, and look at flights from Rome Ciampino Airport, and landing at Brno Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Brno?
The most popular companies between Rome and Brno, are FlixBus, Siam Air Transport and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Siam Air Transport, Ryanair, ITA Airways and 3 more.
All you need to know when you travel from Rome to Brno
Check all information on comfort and services on all modes of transports from Rome to Brno. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Brno
How can I reach Brno from Rome?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Brno from Rome.
How far is Brno from Rome?
The distance between Rome and Brno is 541.7 miles.
What is the most ecofriendly mode of transport between Rome and Brno?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 148 kgs, and a flight 214 kgs.
What is the cheapest mode of transport from Rome to Brno?
You can get to Brno with just $63 by taking a Bus from RegioJet.
What is the fastest way to get from Rome to Brno?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brno in just 1h 40m with a Flight from Siam Air Transport.
More routes to Rome and to Brno
Looking for more options? Here you can see the most popular routes to Rome and to Brno. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Alba Adriatica to Rome
- Avellino to Rome
- Bologna to Rome
- Brindisi to Rome
- Caserta to Rome
- Catania to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitavecchia to Rome
- Frascineto to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Munich to Rome
- Naples to Rome
- Perugia to Rome
- Pescara to Rome
- Pisa to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Teramo to Rome
- Trips to Brno
- Berlin to Brno
- Bratislava to Brno
- Břeclav to Brno
- Ceske Budejovice to Brno
- Humenne to Brno
- Jihlava to Brno
- Levoca to Brno
- Nitra to Brno
- Olomouc to Brno
- Ostrava to Brno
- Piešťany to Brno
- Pilsen to Brno
- Poprad to Brno
- Prague Airport to Brno
- Prague to Brno
- Presov to Brno
- Salzburg to Brno
- Uherský Brod to Brno
- Vienna Airport to Brno
- Vienna to Brno
- Vsetín to Brno
- Warsaw to Brno
- Zlín to Brno
- Zvolen to Brno