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How to get from St. Louis, MO to Pittsburgh

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What is the best way to travel from St. Louis, MO to Pittsburgh?

Looking for a trip? Compare all the available Buses and Flights for the journey to Pittsburgh from St. Louis, MO. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
13h 15m
$81
$103
8
Flight
4h 13m
$349
$475
14

What is the cheapest way to reach Pittsburgh from St. Louis, MO?

You can get to Pittsburgh with just $81 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

today
from $87
tomorrow
from $81
Friday
from $352
Saturday
from $108
Sunday
from $349
Monday
Tuesday

    Cheapest Buses today

  • Greyhound US
    24h 0m
    0
    11:15 PM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    14h 30m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $114
  • Greyhound US
    13h 15m
    0
    1:30 PM
    St. Louis, MO
    Gateway Station
    3:45 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $114
  • Cheapest Flights today

  • United Airlines
    5h 48m
    0
    6:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:18 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $352
  • United Airlines
    5h 23m
    0
    10:10 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    4:33 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $352
  • Skyscanner
    5h 2m
    0
    12:00 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    6:02 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $352
  • Skyscanner
    6h 16m
    0
    7:04 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    2:20 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $526
  • Alaska Airlines
    13h 30m
    0
    7:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    9:30 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from $534

    Cheapest Buses tomorrow

  • Greyhound US
    24h 0m
    0
    11:15 PM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $81
  • Greyhound US
    13h 35m
    0
    12:50 AM
    St. Louis, MO
    Gateway Station
    3:25 PM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $104
  • Greyhound US
    14h 30m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $104
  • Greyhound US
    13h 15m
    0
    1:30 PM
    St. Louis, MO
    Gateway Station
    3:45 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $104

    Cheapest Flights Friday

  • United Airlines
    4h 56m
    0
    5:40 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    11:36 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $352
  • United Airlines
    5h 23m
    0
    10:10 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    4:33 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $420
  • Alaska Airlines
    13h 30m
    0
    7:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    9:30 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from $586
  • Skyscanner
    5h 2m
    0
    12:00 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    6:02 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $668
  • Skyscanner
    4h 34m
    0
    8:25 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:59 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $873

    Cheapest Buses Saturday

  • Greyhound US
    13h 35m
    0
    12:50 AM
    St. Louis, MO
    Gateway Station
    3:25 PM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $108
  • Greyhound US
    14h 30m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $108
  • Greyhound US
    13h 15m
    0
    1:30 PM
    St. Louis, MO
    Gateway Station
    3:45 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $108

    Cheapest Flights Sunday

  • United Airlines
    5h 48m
    0
    6:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:18 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $349
  • United Airlines
    4h 13m
    0
    8:05 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:18 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $349
  • Spirit Airlines
    7h 46m
    0
    4:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:12 AM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Spirit Airlines
    Economy
    from $349
  • Skyscanner
    4h 34m
    0
    8:25 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:59 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $525
  • Alaska Airlines
    13h 30m
    0
    7:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    9:30 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from $532

What are the fastest trips from St. Louis, MO to Pittsburgh?

You can get to Pittsburgh from St. Louis, MO in just 4h 13m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

today
from 5h 2m
tomorrow
from 13h 15m
Friday
from 4h 34m
Saturday
from 13h 15m
Sunday
from 4h 13m
Monday
Tuesday

    Fastest Flights today

  • Skyscanner
    5h 2m
    0
    12:00 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    6:02 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $352
  • United Airlines
    5h 23m
    0
    10:10 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    4:33 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $352
  • United Airlines
    5h 48m
    0
    6:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:18 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $352
  • Skyscanner
    6h 16m
    0
    7:04 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    2:20 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $526
  • Alaska Airlines
    13h 30m
    0
    7:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    9:30 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from $534
  • Fastest Buses today

  • Greyhound US
    13h 15m
    0
    1:30 PM
    St. Louis, MO
    Gateway Station
    3:45 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $114
  • Greyhound US
    14h 30m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $114
  • Greyhound US
    24h 0m
    0
    11:15 PM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $87

    Fastest Buses tomorrow

  • Greyhound US
    13h 15m
    0
    1:30 PM
    St. Louis, MO
    Gateway Station
    3:45 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $104
  • Greyhound US
    13h 35m
    0
    12:50 AM
    St. Louis, MO
    Gateway Station
    3:25 PM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $104
  • Greyhound US
    14h 30m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $104
  • Greyhound US
    24h 0m
    0
    11:15 PM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $81

    Fastest Flights Friday

  • Skyscanner
    4h 34m
    0
    8:25 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:59 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $873
  • United Airlines
    4h 56m
    0
    5:40 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    11:36 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $352
  • Skyscanner
    5h 2m
    0
    12:00 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    6:02 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $668
  • United Airlines
    5h 23m
    0
    10:10 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    4:33 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $420
  • Alaska Airlines
    13h 30m
    0
    7:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    9:30 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from $586

    Fastest Buses Saturday

  • Greyhound US
    13h 15m
    0
    1:30 PM
    St. Louis, MO
    Gateway Station
    3:45 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $108
  • Greyhound US
    13h 35m
    0
    12:50 AM
    St. Louis, MO
    Gateway Station
    3:25 PM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $108
  • Greyhound US
    14h 30m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    12:15 AM
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    $108

    Fastest Flights Sunday

  • United Airlines
    4h 13m
    0
    8:05 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:18 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $349
  • Skyscanner
    4h 34m
    0
    8:25 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:59 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from $525
  • United Airlines
    5h 48m
    0
    6:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:18 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from $349
  • Spirit Airlines
    7h 46m
    0
    4:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:12 AM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Spirit Airlines
    Economy
    from $349
  • Alaska Airlines
    13h 30m
    0
    7:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    9:30 PM
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from $532
Here you will find all operators and timetables for a Bus from St. Louis, MO to Pittsburgh

What are the most popular stations in St. Louis, MO and Pittsburgh?

In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Pittsburgh you will be arriving at David L. Lawrence Convention Center, University of or Central Station, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Pittsburgh from St. Louis, MO? With 5 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Pittsburgh, you can pay as low as $81 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Pittsburgh in just 4h 13m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Pittsburgh are Greyhound US, United Airlines and Skyscanner, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in St. Louis, MO and Pittsburgh is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Green Tree, PA, and look at flights from St. Louis Lambert Airport, and landing at Pittsburgh Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from St. Louis, MO to Pittsburgh?

The most popular companies between St. Louis, MO and Pittsburgh, are Greyhound US, United Airlines and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US

Airlines: United Airlines, Skyscanner, Alaska Airlines and 1 more.

All you need to know when you travel from St. Louis, MO to Pittsburgh

Check all information on comfort and services on all modes of transports from St. Louis, MO to Pittsburgh. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from St. Louis, MO to Pittsburgh

How can I reach Pittsburgh from St. Louis, MO?

Every day, there are on average 5 connections between Bus and Flight, with which you can get to Pittsburgh from St. Louis, MO.

How far is Pittsburgh from St. Louis, MO?

The distance between St. Louis, MO and Pittsburgh is 558.2 miles.

What is the most ecofriendly mode of transport between St. Louis, MO and Pittsburgh?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 153 kgs, and a flight 221 kgs.

What is the cheapest mode of transport from St. Louis, MO to Pittsburgh?

You can get to Pittsburgh with just $81 by taking a Bus from Greyhound US.

What is the fastest way to get from St. Louis, MO to Pittsburgh?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Pittsburgh in just 4h 13m with a Flight from United Airlines.

More routes to St. Louis, MO and to Pittsburgh

Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Pittsburgh. Simply click on a connection, and you’ll find all the details about the route!

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