Bus from Chicago to San Diego from $144

Compare 2 companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Chicago to San Diego

Here is a selection of the cheapest bus trips from the schedule from Chicago to San Diego from various bus operators like Greyhound US or FlixBus for the next days.
today
from $156
tomorrow
from $209
Sunday
Monday
from $144
Tuesday
from $162
Wednesday
from $169
Thursday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    63h 5m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    1:35 PM
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    $156
  • Greyhound US
    51h 20m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    1:50 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $158
  • Greyhound US
    60h 10m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    10:40 AM
    San Diego
    Balboa Park
    0
    Greyhound US
    Economy
    $158
  • FlixBus
    61h 25m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    1:15 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $194
  • FlixBus
    61h 5m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    12:55 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $196

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    55h 20m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $209
  • Greyhound US
    51h 35m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $210
  • Greyhound US
    62h 25m
    0
    8:35 PM
    Chicago
    95th Red Line Station
    11:00 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $211
  • FlixBus
    63h 15m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    3:05 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $221
  • Did you know that if you travel from Chicago to San Diego via Kansas City, you can save more than $33? You can find the corresponding connections below.
    • Busbud
      55h 5m
      0
      6:10 AM
      Chicago
      Downtown Bus Station
      9:00 PM
      Kansas City
      Greyhound Bus Station
      0
      Busbud
      Economy
      $52
      • Waiting Time 1h 20m
    • Busbud
      38h 55m
      0
      10:20 PM
      Kansas City
      Greyhound Bus Station
      1:15 PM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $124
    Travel time is 3h 30m longer, but you will save $33

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    61h 50m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $144
  • Greyhound US
    55h 5m
    0
    4:45 PM
    Chicago
    Downtown Bus Station
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $144
  • Greyhound US
    52h 45m
    0
    4:45 PM
    Chicago
    Downtown Bus Station
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $144
  • Greyhound US
    59h 30m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $146
  • Greyhound US
    56h 10m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $147

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    55h 5m
    0
    4:45 PM
    Chicago
    Downtown Bus Station
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $162
  • Greyhound US
    52h 45m
    0
    4:45 PM
    Chicago
    Downtown Bus Station
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $162
  • Greyhound US
    49h 25m
    0
    4:45 PM
    Chicago
    Downtown Bus Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $164
  • Greyhound US
    48h 50m
    0
    4:45 PM
    Chicago
    Downtown Bus Station
    5:35 PM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $164
  • Greyhound US
    51h 20m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    1:50 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $181

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    60h 10m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    10:40 AM
    San Diego
    Balboa Park
    0
    Greyhound US
    Economy
    $169
  • Greyhound US
    63h 5m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    1:35 PM
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    $170
  • Greyhound US
    54h 45m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    12:55 PM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $178
  • Greyhound US
    55h 5m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    1:15 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $180
  • Greyhound US
    55h 25m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    1:35 PM
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    $180

Frequency of bus connections between Chicago and San Diego

See here how frequent the connections between Chicago and San Diego are, during different times and days of the week.
Friday is the busiest day, with more than 57 daily buses from Chicago to San Diego. Tuesday has instead the fewest connections, with only 20 daily coaches between Chicago and San Diego.
The busiest time of the day is the Evening, with 79 buses from Chicago to San Diego, while Afternoon sees the fewest connections between Chicago and San Diego, with 39 offers.

Facts about the bus from Chicago to San Diego

Compare all providers like Greyhound US and FlixBus that travel 33 times every day by bus from Chicago to San Diego in one click! Book your bus ticket from Chicago to San Diego starting from $144!

Cheapest Bus $144
Fastest Bus 48h 50m
Earliest Bus 6:10 AM
Latest Bus 10:30 PM
Daily Bus Routes 33 Ø
Distance 1,730.9 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Chicago to San Diego

Every day, 33 buses from 2 bus companies leave Chicago for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/16
Monday 03/17
Tuesday 03/18
Wednesday 03/19
Thursday 03/20
Friday 03/21
$156
Saturday 03/22
$209
Sunday 03/23
Monday 03/24
$144
Tuesday 03/25
$162
Wednesday 03/26
$169
Thursday 03/27
Friday 03/28
$162
Saturday 03/29
$235
Sunday 03/30
$131
Monday 03/31
Tuesday 04/01
Wednesday 04/02
Thursday 04/03
Friday 04/04
Saturday 04/05
Sunday 04/06
Monday 04/07
Tuesday 04/08
Wednesday 04/09
Thursday 04/10
Friday 04/11
Saturday 04/12

The cheapest time to travel from Chicago to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to San Diego, for the next 30 days.
With a price starting from $144, Monday is the cheapest day for a bus from Chicago to San Diego. Saturday instead is the most expensive day with prices starting from $209.
Morning is the cheapest day time for bus tickets from Chicago to San Diego, with $144. Evening is the most expensive time of the day with prices starting from $149.

How to save money travelling from Chicago to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to San Diego are also emptier.

All bus stations and stops in Chicago and San Diego

In the map below, you can see where to find all bus stations in Chicago and San Diego.

Service and Comfort on the bus from Chicago to San Diego

Want to know which seat classes are available on the buses from Chicago to San Diego? Or which bus companies serve the route Chicago to San Diego? Below you will find answers to your questions.

FAQs about the Chicago to San Diego bus

How much does a Chicago San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $144 and takes 61h 50m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Chicago to San Diego?

This route is offered by 2 companies with a range of ticket prices between $144 and $366. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Chicago to San Diego each day?

Every day, the Chicago to San Diego bus route is served by approximately 33 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to San Diego take?

The fastest bus from Chicago to San Diego is offered by Greyhound US and takes 48h 50m. Bus tickets for this connection cost $151. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to San Diego?

The earliest bus arriving in San Diego from Chicago starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to San Diego?

The latest bus trip departing from Chicago for San Diego starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago San Diego route?

When traveling by bus from Chicago to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and San Diego?

You can check all the direct connections between Chicago and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Chicago to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to San Diego

Here’s an overview of the most popular bus routes to Chicago and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses St. Louis, MO to Chicago Buses St. Louis, MO to Chicago
Buses to Chicago from Atlanta, GA Buses to Chicago from Atlanta, GA
Bus from Lafayette, IN to Chicago Bus from Lafayette, IN to Chicago
Buses Ann Arbor, MI to Chicago Buses Ann Arbor, MI to Chicago
Buses to San Diego from Palm Springs, CA Buses to San Diego from Palm Springs, CA
Buses to San Diego from Tijuana, BC Buses to San Diego from Tijuana, BC
Buses San Francisco - San Diego Buses San Francisco - San Diego
Bus from Santa Monica, CA to San Diego Bus from Santa Monica, CA to San Diego
Popular Airport Shuttles to Chicago and to San Diego
CheckMyBus › Buses in USA › Bus to Chicago › Bus to San Diego

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.