Bus Frankfurt am Main to Rome: Compare prices and save money

Compare all timetables for the bus from Frankfurt am Main to Rome

Here is a selection of the cheapest bus trips from the schedule from Frankfurt am Main to Rome from various bus operators like FlixBus for the next days.

today

from $157

tomorrow

from $139

Monday

from $127

Tuesday

from $117

Wednesday

from $122

Thursday

from $123

Friday

from $143

Cheapest bus trips today

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$157	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2025 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/27/2025 9:30:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 19h 45m
FlixBus	22h 50m	2:30 PM	Frankfurt am Main	Central Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$158	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2025 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/27/2025 1:20:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 22h 50m
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$164	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/27/2025 1:50:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 20h 5m
FlixBus	21h 30m	2:45 PM	Frankfurt am Main	Central Station	12:15 PM	Rome	Anagnina Bus Station	Economy	$166	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2025 2:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 7/27/2025 12:15:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 21h 30m
FlixBus	21h 20m	5:45 PM	Frankfurt am Main	Central Station	3:05 PM	Rome	Anagnina Bus Station	Economy	$166	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2025 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 7/27/2025 3:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 21h 20m

Did you know that if you travel from Frankfurt am Main to Rome via Verona, you can save more than $49? You can find the corresponding connections below.
- FlixBus
  
  23h 45m
  
  0
  
  4:15 AM
  
  Frankfurt am Main
  Central Station
  
  4:40 PM
  
  Verona
  Porta Nuova Bus Station
  
  0
  
  Economy
  
  $72
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 4:15:00 AM to Porta Nuova Bus Station, Verona (Italy) arriving at 7/28/2025 4:40:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 12h 25m
- FlixBus
  
  7h 10m
  
  0
  
  8:50 PM
  
  Verona
  Porta Nuova Bus Station
  
  4:00 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Porta Nuova Bus Station, Verona (Italy) at 7/28/2025 8:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 4:00:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 10m
Travel time is 4h 0m longer, but you will save $49

Cheapest bus trips tomorrow

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 20m	11:10 AM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$139	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2025 11:10:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2025 9:30:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 22h 20m
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$143	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2025 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/27/2025 11:00:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 21h 20m
FlixBus	18h 55m	10:30 PM	Frankfurt am Main	Central Station	5:25 PM	Rome	Tiburtina Bus Station	Economy	$150	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2025 10:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2025 5:25:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 18h 55m
FlixBus	21h 30m	2:45 PM	Frankfurt am Main	Central Station	12:15 PM	Rome	Anagnina Bus Station	Economy	$150	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2025 2:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 7/28/2025 12:15:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 21h 30m
FlixBus	22h 20m	7:15 AM	Frankfurt am Main	Central Station	5:35 AM	Rome	Tiburtina Bus Station	Economy	$151	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2025 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2025 5:35:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 22h 20m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $36? You can find the corresponding connections below.
- FlixBus
  
  25h 55m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $88
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 7/29/2025 8:25:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 14h 40m
- Distribusion
  
  4h 40m
  
  0
  
  3:00 PM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  7:40 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $15
  
  A Bus from Distribusion goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 7/29/2025 3:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 7:40:00 PM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 4h 40m
Travel time is 7h 0m longer, but you will save $36

Cheapest bus trips Monday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 55m	10:30 PM	Frankfurt am Main	Central Station	5:25 PM	Rome	Tiburtina Bus Station	Economy	$127	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 10:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 5:25:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 18h 55m
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$129	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2025 11:00:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 21h 20m
FlixBus	19h 30m	10:30 PM	Frankfurt am Main	Central Station	6:00 PM	Rome	Anagnina Bus Station	Economy	$129	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 10:30:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 7/29/2025 6:00:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 19h 30m
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$133	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 1:50:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 20h 5m
FlixBus	21h 40m	11:00 AM	Frankfurt am Main	Central Station	8:40 AM	Rome	Tiburtina Bus Station	Economy	$135	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2025 11:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 8:40:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 21h 40m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $37? You can find the corresponding connections below.
- FlixBus
  
  20h 20m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $80
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 7/30/2025 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 40m
- FlixBus
  
  5h 0m
  
  0
  
  9:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  2:05 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 7/30/2025 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 2:05:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 5h 0m
Travel time is 1h 25m longer, but you will save $37

Cheapest bus trips Tuesday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$117	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 11:00:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 21h 20m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$120	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 9:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 19h 45m
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$122	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 1:50:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 20h 5m
FlixBus	22h 10m	8:10 PM	Frankfurt am Main	Central Station	6:20 PM	Rome	Anagnina Bus Station	Economy	$122	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 8:10:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 7/30/2025 6:20:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 22h 10m
FlixBus	20h 25m	12:45 AM	Frankfurt am Main	Central Station	9:10 PM	Rome	Tiburtina Bus Station	Economy	$126	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 12:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2025 9:10:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 20h 25m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $27? You can find the corresponding connections below.
- FlixBus
  
  20h 20m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $80
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 7/30/2025 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 40m
- FlixBus
  
  5h 0m
  
  0
  
  9:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  2:05 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 7/30/2025 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 2:05:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 5h 0m
Travel time is 0h 35m longer, but you will save $27

Cheapest bus trips Wednesday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$122	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/31/2025 1:50:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 20h 5m
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$123	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2025 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 11:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 21h 20m
FlixBus	22h 50m	2:30 PM	Frankfurt am Main	Central Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$126	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2025 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/31/2025 1:20:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 22h 50m
FlixBus	21h 30m	2:45 PM	Frankfurt am Main	Central Station	12:15 PM	Rome	Anagnina Bus Station	Economy	$130	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2025 2:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 7/31/2025 12:15:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 30m
FlixBus	20h 25m	12:45 AM	Frankfurt am Main	Central Station	9:10 PM	Rome	Tiburtina Bus Station	Economy	$134	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2025 12:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 9:10:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 25m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $32? You can find the corresponding connections below.
- FlixBus
  
  20h 20m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $80
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 7/30/2025 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 40m
- FlixBus
  
  5h 0m
  
  0
  
  9:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  2:05 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 7/30/2025 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 2:05:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 5h 0m
Travel time is 0h 15m longer, but you will save $32

Cheapest bus trips Thursday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$123	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2025 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/31/2025 11:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 21h 20m
FlixBus	22h 20m	11:10 AM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$123	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2025 11:10:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 8/1/2025 9:30:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 22h 20m
FlixBus	21h 30m	2:45 PM	Frankfurt am Main	Central Station	12:15 PM	Rome	Anagnina Bus Station	Economy	$128	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2025 2:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 8/1/2025 12:15:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 21h 30m
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$137	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/1/2025 1:50:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 20h 5m
FlixBus	22h 5m	9:00 AM	Frankfurt am Main	Central Station	7:05 AM	Rome	Tiburtina Bus Station	Economy	$139	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2025 9:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 8/1/2025 7:05:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 22h 5m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $33? You can find the corresponding connections below.
- FlixBus
  
  20h 20m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $80
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 7/30/2025 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 40m
- FlixBus
  
  5h 0m
  
  0
  
  9:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  2:05 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 7/30/2025 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 2:05:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 5h 0m
Travel time is 0h 15m longer, but you will save $33

Cheapest bus trips Friday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 45m	4:15 AM	Frankfurt am Main	Central Station	4:00 AM	Rome	Tiburtina Bus Station	Economy	$143	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2025 4:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 8/2/2025 4:00:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 23h 45m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$149	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2025 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/2/2025 9:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 19h 45m
FlixBus	18h 55m	10:30 PM	Frankfurt am Main	Central Station	5:25 PM	Rome	Tiburtina Bus Station	Economy	$149	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2025 10:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/2/2025 5:25:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 18h 55m
FlixBus	22h 20m	7:15 AM	Frankfurt am Main	Central Station	5:35 AM	Rome	Tiburtina Bus Station	Economy	$151	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2025 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 8/2/2025 5:35:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 22h 20m
FlixBus	22h 50m	7:15 AM	Frankfurt am Main	Central Station	6:05 AM	Rome	Anagnina Bus Station	Economy	$151	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2025 7:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 8/2/2025 6:05:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 22h 50m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $53? You can find the corresponding connections below.
- FlixBus
  
  20h 20m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $80
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2025 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 7/30/2025 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 40m
- FlixBus
  
  5h 0m
  
  0
  
  9:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  2:05 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 7/30/2025 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/30/2025 2:05:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 5h 0m
Travel time is 1h 25m longer, but you will save $53

Frequency of bus connections between Frankfurt am Main and Rome

See here how frequent the connections between Frankfurt am Main and Rome are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily buses from Frankfurt am Main to Rome. Wednesday has instead the fewest connections, with only 12 daily coaches between Frankfurt am Main and Rome.

The busiest time of the day is the Afternoon, with 33 buses from Frankfurt am Main to Rome, while Evening sees the fewest connections between Frankfurt am Main and Rome, with 15 offers.

Facts about the bus from Frankfurt am Main to Rome

Compare all providers like FlixBus that travel 13 times every day by bus from Frankfurt am Main to Rome in one click! Book your bus ticket from Frankfurt am Main to Rome starting from $117!

Cheapest Bus	$117
Fastest Bus	18h 55m
Earliest Bus	12:45 AM
Latest Bus	10:30 PM
Daily Bus Routes	13 Ø
Distance	596.0 miles
Bus Companies	FlixBus

Cheapest bus connections from Frankfurt am Main to Rome

Every day, 13 buses from 1 bus companies leave Frankfurt am Main for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/20

Monday 07/21

Tuesday 07/22

Wednesday 07/23

Thursday 07/24

Friday 07/25

Saturday 07/26

$157

Sunday 07/27

$139

Monday 07/28

$127

Tuesday 07/29

$117

Wednesday 07/30

$122

Thursday 07/31

$122

Friday 08/01

$143

Saturday 08/02

$129

Sunday 08/03

$124

Monday 08/04

$110

Tuesday 08/05

$105

Wednesday 08/06

$110

Thursday 08/07

$99

Friday 08/08

$104

Saturday 08/09

$114

Sunday 08/10

$121

Monday 08/11

$102

Tuesday 08/12

$97

Wednesday 08/13

$115

Thursday 08/14

$100

Friday 08/15

$109

Saturday 08/16

The cheapest time to travel from Frankfurt am Main to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Frankfurt am Main to Rome, for the next 30 days.

With a price starting from $117, Tuesday is the cheapest day for a bus from Frankfurt am Main to Rome. Saturday instead is the most expensive day with prices starting from $157.

Night is the cheapest day time for bus tickets from Frankfurt am Main to Rome, with $117. Morning is the most expensive time of the day with prices starting from $123.

How to save money travelling from Frankfurt am Main to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frankfurt am Main to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frankfurt am Main to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frankfurt am Main to Rome are also emptier.

All bus stations and stops in Frankfurt am Main and Rome

In the map below, you can see where to find all bus stations in Frankfurt am Main and Rome.

Central Bus Station

Karlsruher Straße 10

Stuttgarter Strasse Bus Stop

Stuttgarter Str.

Seilerstraße Bus Stop

Baseler Platz Bus Stop

Stresemannallee/Mörfelder Landstr. Bus Stop

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Service and Comfort on the bus from Frankfurt am Main to Rome

Want to know which seat classes are available on the buses from Frankfurt am Main to Rome? Or which bus companies serve the route Frankfurt am Main to Rome? Below you will find answers to your questions.

FAQs about the Frankfurt am Main to Rome bus

How much does a Frankfurt am Main Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $117 and takes 21h 20m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Frankfurt am Main to Rome?

This route is offered by 1 companies with a range of ticket prices between $117 and $215. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Frankfurt am Main to Rome each day?

Every day, the Frankfurt am Main to Rome bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frankfurt am Main to Rome take?

The fastest bus from Frankfurt am Main to Rome is offered by FlixBus and takes 18h 55m. Bus tickets for this connection cost $150. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frankfurt am Main to Rome?

The earliest bus arriving in Rome from Frankfurt am Main starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frankfurt am Main to Rome?

The latest bus trip departing from Frankfurt am Main for Rome starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frankfurt am Main Rome route?

When traveling by bus from Frankfurt am Main to Rome, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frankfurt am Main and Rome?

You can check all the direct connections between Frankfurt am Main and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Frankfurt am Main to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frankfurt am Main Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frankfurt am Main Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frankfurt am Main to Rome on your planned travel date.

Available seat classes which are offered on the bus route Frankfurt am Main to Rome

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frankfurt am Main and to Rome

Here’s an overview of the most popular bus routes to Frankfurt am Main and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!