Bus from Siena to Rome from $6

Compare 3 companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Siena to Rome

Here is a selection of the cheapest bus trips from the schedule from Siena to Rome from various bus operators like Itabus, FlixBus or MarinoBus for the next days.
today
from $8
tomorrow
from $6
Monday
from $8
Tuesday
from $6
Wednesday
from $7
Thursday
from $6
Friday
from $6

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    2h 45m
    0
    10:25 PM
    Siena
    Train Station
    1:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • FlixBus
    3h 11m
    0
    11:39 PM
    Siena
    Bus Stop
    2:50 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $9
  • Itabus
    2h 50m
    0
    3:50 PM
    Siena
    Train Station
    6:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $9
  • Itabus
    2h 50m
    0
    6:40 PM
    Siena
    Train Station
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $9
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Central Bus Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $30

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    2h 50m
    0
    10:30 AM
    Siena
    Train Station
    1:20 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $6
  • FlixBus
    2h 40m
    0
    10:40 AM
    Siena
    Bus Stop
    1:20 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $6
  • Itabus
    2h 50m
    0
    6:40 PM
    Siena
    Train Station
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $14
  • Itabus
    2h 50m
    0
    4:10 AM
    Siena
    Train Station
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $17
  • MarinoBus
    4h 10m
    0
    7:30 PM
    Siena
    Train Station
    11:40 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $27

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    2h 45m
    0
    12:05 AM
    Siena
    Train Station
    2:50 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • FlixBus
    2h 45m
    0
    10:25 PM
    Siena
    Train Station
    1:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • Itabus
    2h 50m
    0
    5:05 AM
    Siena
    Train Station
    7:55 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $8
  • Itabus
    2h 50m
    0
    5:05 AM
    Siena
    Central Bus Station
    7:55 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $9
  • MarinoBus
    4h 10m
    0
    7:30 PM
    Siena
    Central Bus Station
    11:40 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $35

Cheapest bus trips Tuesday

Prices are for one way and one person
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Train Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $6
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Train Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $6
  • FlixBus
    2h 45m
    0
    10:25 PM
    Siena
    Train Station
    1:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $7
  • FlixBus
    2h 45m
    0
    12:05 AM
    Siena
    Train Station
    2:50 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • Itabus
    2h 50m
    0
    5:05 PM
    Siena
    Train Station
    7:55 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $10

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    3h 5m
    0
    5:35 AM
    Siena
    Train Station
    8:40 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $7
  • FlixBus
    2h 55m
    0
    7:15 AM
    Siena
    Train Station
    10:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • Itabus
    2h 50m
    0
    11:25 AM
    Siena
    Central Bus Station
    2:15 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $10
  • Itabus
    2h 50m
    0
    3:50 PM
    Siena
    Central Bus Station
    6:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $11
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Central Bus Station
    2:20 PM
    Rome
    Tiburtina Train Station
    0
    MarinoBus
    Economy
    $24

Cheapest bus trips Thursday

Prices are for one way and one person
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Train Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $6
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Central Bus Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $7
  • Itabus
    2h 50m
    0
    11:25 AM
    Siena
    Train Station
    2:15 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $8
  • FlixBus
    3h 5m
    0
    5:35 AM
    Siena
    Train Station
    8:40 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • FlixBus
    2h 55m
    0
    7:15 AM
    Siena
    Train Station
    10:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8

Cheapest bus trips Friday

Prices are for one way and one person
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Train Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $6
  • MarinoBus
    3h 5m
    0
    11:15 AM
    Siena
    Central Bus Station
    2:20 PM
    Rome
    Tiburtina Bus Station
    0
    MarinoBus
    Economy
    $6
  • FlixBus
    2h 45m
    0
    9:00 PM
    Siena
    Train Station
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $8
  • FlixBus
    2h 45m
    0
    6:25 PM
    Siena
    Train Station
    9:10 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $9
  • Itabus
    2h 50m
    0
    5:05 PM
    Siena
    Central Bus Station
    7:55 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $9

Frequency of bus connections between Siena and Rome

See here how frequent the connections between Siena and Rome are, during different times and days of the week.
Saturday is the busiest day, with more than 66 daily buses from Siena to Rome. Sunday has instead the fewest connections, with only 22 daily coaches between Siena and Rome.
The busiest time of the day is the Morning, with 139 buses from Siena to Rome, while Night sees the fewest connections between Siena and Rome, with 46 offers.

Facts about the bus from Siena to Rome

Compare all providers like Itabus, FlixBus and MarinoBus that travel 45 times every day by bus from Siena to Rome in one click! Book your bus ticket from Siena to Rome starting from $6!

Cheapest Bus $6
Fastest Bus 2h 40m
Earliest Bus 12:05 AM
Latest Bus 11:39 PM
Daily Bus Routes 45 Ø
Distance 114.5 miles
Bus Companies Itabus, FlixBus and MarinoBus

Cheapest bus connections from Siena to Rome

Every day, 45 buses from 3 bus companies leave Siena for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/13
Monday 04/14
Tuesday 04/15
Wednesday 04/16
Thursday 04/17
Friday 04/18
Saturday 04/19
$15
Sunday 04/20
$8
Monday 04/21
$8
Tuesday 04/22
$6
Wednesday 04/23
$7
Thursday 04/24
$6
Friday 04/25
$6
Saturday 04/26
$6
Sunday 04/27
$8
Monday 04/28
$7
Tuesday 04/29
$6
Wednesday 04/30
$7
Thursday 05/01
$7
Friday 05/02
$6
Saturday 05/03
Sunday 05/04
$6
Monday 05/05
$10
Tuesday 05/06
$6
Wednesday 05/07
$10
Thursday 05/08
$7
Friday 05/09
$6
Saturday 05/10

The cheapest time to travel from Siena to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Siena to Rome, for the next 30 days.
With a price starting from $6, Tuesday is the cheapest day for a bus from Siena to Rome. Saturday instead is the most expensive day with prices starting from $8.
Morning is the cheapest day time for bus tickets from Siena to Rome, with $6. Afternoon is the most expensive time of the day with prices starting from $8.

How to save money travelling from Siena to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siena to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siena to Rome are also emptier.

Beloved bus companies from Siena to Rome

These are the most booked bus companies between Siena to Rome from our users.

FlixBus from Siena to Rome

FlixBus

Here you will find the key facts about the FlixBus bus route Siena to Rome:

Cheapest Price $6
Fastest Bus 2h 40m
Earliest Bus 12:05 AM
Last Bus 11:39 PM
Daily Connections 17 Ø
Found on 4/18/2025

Itabus from Siena to Rome

Itabus

Here you will find the key facts about the Itabus bus route Siena to Rome:

Cheapest Price $8
Fastest Bus 2h 50m
Earliest Bus 4:10 AM
Last Bus 6:40 PM
Daily Connections 19 Ø
Found on 4/18/2025

MarinoBus from Siena to Rome

MarinoBus

Here you will find the key facts about the MarinoBus bus route Siena to Rome:

Cheapest Price $6
Fastest Bus 3h 5m
Earliest Bus 11:15 AM
Last Bus 8:30 PM
Daily Connections 7 Ø
Found on 4/18/2025

All bus stations and stops in Siena and Rome

In the map below, you can see where to find all bus stations in Siena and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Siena to Rome? Compare all modes of transports from Siena to Rome.

Service and Comfort on the bus from Siena to Rome

Want to know which seat classes are available on the buses from Siena to Rome? Or which bus companies serve the route Siena to Rome? Below you will find answers to your questions.

FAQs about the Siena to Rome bus

How much does a Siena Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $6 and takes 3h 5m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Siena to Rome?

This route is offered by 3 companies with a range of ticket prices between $6 and $103. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Siena to Rome each day?

Every day, the Siena to Rome bus route is served by approximately 45 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Siena to Rome take?

The fastest bus from Siena to Rome is offered by FlixBus and takes 2h 40m. Bus tickets for this connection cost $14. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Siena to Rome?

The earliest bus arriving in Rome from Siena starts at 12:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Siena to Rome?

The latest bus trip departing from Siena for Rome starts at 11:39 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Siena Rome route?

When traveling by bus from Siena to Rome, passengers can travel with Itabus, FlixBus and MarinoBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Siena and Rome?

You can check all the direct connections between Siena and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, FlixBus and MarinoBus.

What can I take with me on the Siena to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Siena Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Siena Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siena to Rome on your planned travel date.

Available seat classes which are offered on the bus route Siena to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Siena and to Rome

Here’s an overview of the most popular bus routes to Siena and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Florence to Siena bus From Florence to Siena bus
Bus from Lucca to Siena Bus from Lucca to Siena
Buses Perugia to Siena Buses Perugia to Siena
Bus from Bologna to Siena Bus from Bologna to Siena
Bus from Sorrento to Rome Bus from Sorrento to Rome
Buses Pescara to Rome Buses Pescara to Rome
Buses to Rome from Amalfi Buses to Rome from Amalfi
From Assisi to Rome bus From Assisi to Rome bus
Popular Airport Shuttles to Siena and to Rome
CheckMyBus › Buses in Italy › Bus to Siena › Bus to Rome

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.