Bus from Lexington, KY to St. Louis, MO from $55

Compare 1 companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Lexington, KY to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Lexington, KY to St. Louis, MO from various bus operators like Greyhound US for the next days.
today
from $65
tomorrow
Sunday
from $88
Monday
from $67
Tuesday
from $61
Wednesday
Thursday
from $55

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Lexington, KY
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $65

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Lexington, KY
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $88
  • Did you know that if you travel from Lexington, KY to St. Louis, MO via Cincinnati, you can save more than $17? You can find the corresponding connections below.
    • FlixBus
      8h 50m
      0
      2:45 PM
      Lexington, KY
      Greyhound Bus Station
      4:25 PM
      Cincinnati
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $20
      • Waiting Time 0h 35m
    • Busbud
      6h 35m
      0
      5:00 PM
      Cincinnati
      E Galbraith Rd
      11:35 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $50
    Travel time is the same as the direct connection, but you will save $17

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Lexington, KY
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $67

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Lexington, KY
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $61

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Lexington, KY
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $55
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Lexington, KY
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $57

Facts about the bus from Lexington, KY to St. Louis, MO

Compare all providers like Greyhound US that travel 1 times every day by bus from Lexington, KY to St. Louis, MO in one click! Book your bus ticket from Lexington, KY to St. Louis, MO starting from $55!

Cheapest Bus $55
Fastest Bus 8h 50m
Earliest Bus 2:45 PM
Latest Bus 2:45 PM
Daily Bus Routes 1 Ø
Distance 311.9 miles
Bus Companies Greyhound US

Cheapest bus connections from Lexington, KY to St. Louis, MO

Every day, 1 buses from 1 bus companies leave Lexington, KY for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/25/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/20
Monday 04/21
Tuesday 04/22
Wednesday 04/23
Thursday 04/24
Friday 04/25
$65
Saturday 04/26
Sunday 04/27
$88
Monday 04/28
$67
Tuesday 04/29
$61
Wednesday 04/30
Thursday 05/01
$55
Friday 05/02
$64
Saturday 05/03
Sunday 05/04
Monday 05/05
Tuesday 05/06
Wednesday 05/07
Thursday 05/08
Friday 05/09
Saturday 05/10
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
Friday 05/16
Saturday 05/17

How to save money travelling from Lexington, KY to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lexington, KY to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lexington, KY to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lexington, KY to St. Louis, MO are also emptier.

Beloved bus companies from Lexington, KY to St. Louis, MO

These are the most booked bus companies between Lexington, KY to St. Louis, MO from our users.

Greyhound US from Lexington, KY to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Lexington, KY to St. Louis, MO:

Cheapest Price $55
Fastest Bus 8h 50m
Earliest Bus 2:45 PM
Last Bus 2:45 PM
Daily Connections 1 Ø
Found on 4/23/2025

All bus stations and stops in Lexington, KY and St. Louis, MO

In the map below, you can see where to find all bus stations in Lexington, KY and St. Louis, MO.

Service and Comfort on the bus from Lexington, KY to St. Louis, MO

Want to know which seat classes are available on the buses from Lexington, KY to St. Louis, MO? Or which bus companies serve the route Lexington, KY to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Lexington, KY to St. Louis, MO bus

How much does a Lexington, KY St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $55 and takes 8h 50m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Lexington, KY to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $55 and $88. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Lexington, KY to St. Louis, MO each day?

Every day, the Lexington, KY to St. Louis, MO bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lexington, KY to St. Louis, MO take?

The fastest bus from Lexington, KY to St. Louis, MO is offered by Greyhound US and takes 8h 50m. Bus tickets for this connection cost $65. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lexington, KY to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Lexington, KY starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lexington, KY to St. Louis, MO?

The latest bus trip departing from Lexington, KY for St. Louis, MO starts at 2:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lexington, KY St. Louis, MO route?

When traveling by bus from Lexington, KY to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lexington, KY and St. Louis, MO?

You can check all the direct connections between Lexington, KY and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Lexington, KY to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lexington, KY St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lexington, KY St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lexington, KY to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Lexington, KY to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lexington, KY and to St. Louis, MO

Here’s an overview of the most popular bus routes to Lexington, KY and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Knoxville, TN to Lexington, KY Bus from Knoxville, TN to Lexington, KY
Buses from Charlotte to Lexington, KY Buses from Charlotte to Lexington, KY
Buses Cleveland - Lexington, KY Buses Cleveland - Lexington, KY
Cincinnati to Lexington, KY bus Cincinnati to Lexington, KY bus
Buses to St. Louis, MO from Columbus, OH Buses to St. Louis, MO from Columbus, OH
Bus Wichita, KS to St. Louis, MO Bus Wichita, KS to St. Louis, MO
Bus Las Vegas - St. Louis, MO Bus Las Vegas - St. Louis, MO
From Evansville, IN to St. Louis, MO bus From Evansville, IN to St. Louis, MO bus
Popular Airport Shuttles to Lexington, KY and to St. Louis, MO
CheckMyBus › Buses in USA › Bus to Lexington, KY › Bus to St. Louis, MO

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.