Bus from Houston to St. Louis, MO from $110

Compare 3 companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Houston to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Houston to St. Louis, MO from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.
today
tomorrow
from $123
Friday
Saturday
from $124
Sunday
from $134
Monday
from $110
Tuesday
from $115

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • FlixBus
    29h 40m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $123
  • FlixBus
    25h 5m
    0
    11:10 AM
    Houston
    Downtown Houston
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $123
  • Greyhound US
    22h 5m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $124
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $130

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    22h 30m
    0
    1:45 PM
    Houston
    Main St & Airline Dr
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $124
  • Greyhound US
    22h 5m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $125
  • Greyhound US
    27h 10m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $125
  • FlixBus
    32h 45m
    0
    1:15 PM
    Houston
    Uptown/Upper Kirby
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $125
  • FlixBus
    22h 45m
    0
    1:30 PM
    Houston
    Downtown Houston
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $125

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    22h 5m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $134
  • FlixBus
    29h 0m
    0
    7:15 AM
    Houston
    Uptown/Upper Kirby
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $134
  • FlixBus
    22h 30m
    0
    1:45 PM
    Houston
    Main St & Airline Dr
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $134
  • FlixBus
    29h 40m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $136
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $146
  • Did you know that if you travel from Houston to St. Louis, MO via Memphis, you can save more than $20? You can find the corresponding connections below.
    • Busbud
      22h 5m
      0
      2:10 PM
      Houston
      Harrisburg Blvd Station
      3:35 AM
      Memphis
      Airways Transit Center
      0
      Busbud
      Economy
      $72
      • Waiting Time 1h 5m
    • Busbud
      7h 35m
      0
      4:40 AM
      Memphis
      Airways Transit Center
      12:15 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $42
    Travel time is the same as the direct connection, but you will save $20

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    27h 10m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • Greyhound Lines Mexico
    36h 5m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $110
  • Greyhound US
    22h 5m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $111
  • FlixBus
    26h 50m
    0
    7:50 PM
    Houston
    Uptown/Upper Kirby
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $111
  • FlixBus
    26h 20m
    0
    7:50 PM
    Houston
    Uptown/Upper Kirby
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $111

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    26h 50m
    0
    7:50 PM
    Houston
    Uptown/Upper Kirby
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $115
  • FlixBus
    27h 5m
    0
    7:35 PM
    Houston
    Downtown Houston
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $115
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $116
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $117

Frequency of bus connections between Houston and St. Louis, MO

See here how frequent the connections between Houston and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 26 daily buses from Houston to St. Louis, MO. Sunday has instead the fewest connections, with only 11 daily coaches between Houston and St. Louis, MO.
The busiest time of the day is the Afternoon, with 37 buses from Houston to St. Louis, MO, while Night sees the fewest connections between Houston and St. Louis, MO, with 13 offers.

Facts about the bus from Houston to St. Louis, MO

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 21 times every day by bus from Houston to St. Louis, MO in one click! Book your bus ticket from Houston to St. Louis, MO starting from $110!

Cheapest Bus $110
Fastest Bus 20h 10m
Earliest Bus 2:00 AM
Latest Bus 7:50 PM
Daily Bus Routes 21 Ø
Distance 680.5 miles
Bus Companies FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to St. Louis, MO

Every day, 21 buses from 3 bus companies leave Houston for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/24/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/20
Monday 04/21
Tuesday 04/22
Wednesday 04/23
Thursday 04/24
$123
Friday 04/25
Saturday 04/26
$124
Sunday 04/27
$134
Monday 04/28
$110
Tuesday 04/29
$117
Wednesday 04/30
Thursday 05/01
$140
Friday 05/02
Saturday 05/03
$109
Sunday 05/04
Monday 05/05
$123
Tuesday 05/06
$110
Wednesday 05/07
$104
Thursday 05/08
Friday 05/09
Saturday 05/10
$114
Sunday 05/11
$107
Monday 05/12
$113
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
Friday 05/16
Saturday 05/17

The cheapest time to travel from Houston to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to St. Louis, MO, for the next 30 days.
With a price starting from $110, Monday is the cheapest day for a bus from Houston to St. Louis, MO. Sunday instead is the most expensive day with prices starting from $134.
Morning is the cheapest day time for bus tickets from Houston to St. Louis, MO, with $110. Night is the most expensive time of the day with prices starting from $117.

How to save money travelling from Houston to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to St. Louis, MO are also emptier.

All bus stations and stops in Houston and St. Louis, MO

In the map below, you can see where to find all bus stations in Houston and St. Louis, MO.

Service and Comfort on the bus from Houston to St. Louis, MO

Want to know which seat classes are available on the buses from Houston to St. Louis, MO? Or which bus companies serve the route Houston to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Houston to St. Louis, MO bus

How much does a Houston St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 36h 5m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Houston to St. Louis, MO?

This route is offered by 3 companies with a range of ticket prices between $110 and $159. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Houston to St. Louis, MO each day?

Every day, the Houston to St. Louis, MO bus route is served by approximately 21 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to St. Louis, MO take?

The fastest bus from Houston to St. Louis, MO is offered by Greyhound US and takes 20h 10m. Bus tickets for this connection cost $139. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to St. Louis, MO?

The latest bus trip departing from Houston for St. Louis, MO starts at 7:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston St. Louis, MO route?

When traveling by bus from Houston to St. Louis, MO, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and St. Louis, MO?

You can check all the direct connections between Houston and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Houston to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to St. Louis, MO

Here’s an overview of the most popular bus routes to Houston and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus New Orleans, LA - Houston Bus New Orleans, LA - Houston
Bus College Station, TX - Houston Bus College Station, TX - Houston
Buses Fort Worth - Houston Buses Fort Worth - Houston
Buses Waco, TX - Houston Buses Waco, TX - Houston
Bus Charlotte to St. Louis, MO Bus Charlotte to St. Louis, MO
Bus Springfield, IL - St. Louis, MO Bus Springfield, IL - St. Louis, MO
Bus Kansas City to St. Louis, MO Bus Kansas City to St. Louis, MO
From Atlanta, GA to St. Louis, MO bus From Atlanta, GA to St. Louis, MO bus
Popular Airport Shuttles to Houston and to St. Louis, MO
CheckMyBus › Buses in USA › Bus to Houston › Bus to St. Louis, MO

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.