Bus from Messina to Rome from $21

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Compare all timetables for the bus from Messina to Rome

Here is a selection of the cheapest bus trips from the schedule from Messina to Rome from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.
today
from $22
tomorrow
from $24
Monday
from $21
Tuesday
from $22
Wednesday
from $22
Thursday
from $23
Friday
from $21

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    13h 25m
    0
    4:10 PM
    Messina
    Piazza della Repubblica
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $22
  • FlixBus
    10h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $23
  • FlixBus
    9h 35m
    0
    9:30 PM
    Messina
    Piazza della Repubblica
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $26
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $50
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $9? You will find the corresponding connections below.
    • Save more than 41%
      10h 35m
      Messina
      8 mi
      7:20 PM
      Reggio Calabria
      Via Caprera / Piazza Giuseppe Garibaldi
      5:55 AM
      Rome
      Tiburtina Bus Station
      0 mi
      Economy
      $13
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $8? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $8

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    10h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $24
  • Itabus
    13h 50m
    0
    11:50 PM
    Messina
    Piazza della Repubblica
    1:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $25
  • Itabus
    9h 35m
    0
    10:15 PM
    Messina
    Central Station
    7:50 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $28
  • FlixBus
    13h 25m
    0
    4:10 PM
    Messina
    Piazza della Repubblica
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $35
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Central Station
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $51
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $3? You will find the corresponding connections below.
    • FlixBus
      Save more than 12%
      10h 35m
      Messina
      8 mi
      8:50 PM
      Reggio Calabria
      Central Station
      7:25 AM
      Rome
      Anagnina Bus Station
      0 mi
      FlixBus
      Economy
      $21
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $10? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $10

Cheapest bus trips Monday

Prices are for one way and one person
  • Itabus
    13h 50m
    0
    11:50 PM
    Messina
    Central Station
    1:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $21
  • Itabus
    13h 50m
    0
    11:50 PM
    Messina
    Piazza della Repubblica
    1:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $22
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $28
  • FlixBus
    10h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $29
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Central Station
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $29
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $3? You will find the corresponding connections below.
    • Save more than 14%
      10h 35m
      Messina
      8 mi
      7:20 PM
      Reggio Calabria
      Central Station
      5:55 AM
      Rome
      Tiburtina Bus Station
      0 mi
      Premium Economy
      $18
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $7? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $7

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    10h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $22
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $51
  • FlixBus
    13h 25m
    0
    4:10 PM
    Messina
    Piazza della Repubblica
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $76
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $-6? You will find the corresponding connections below.
    • 9h 30m
      Messina
      8 mi
      4:00 AM
      Reggio Calabria
      Central Station
      1:30 PM
      Rome
      Tiburtina Bus Station
      0 mi
      Economy
      $28
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $8? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $8

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $22
  • FlixBus
    10h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $24
  • FlixBus
    12h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    11:30 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $50
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $54
  • FlixBus
    9h 20m
    0
    10:50 PM
    Messina
    Piazza della Repubblica
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $67
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $7? You will find the corresponding connections below.
    • Save more than 32%
      10h 35m
      Messina
      8 mi
      7:20 PM
      Reggio Calabria
      Via Caprera / Piazza Giuseppe Garibaldi
      5:55 AM
      Rome
      Tiburtina Bus Station
      0 mi
      Economy
      $15
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $8? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $8

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    10h 35m
    0
    10:55 AM
    Messina
    Piazza della Repubblica
    9:30 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $23
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $28
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $28
  • FlixBus
    9h 35m
    0
    9:30 PM
    Messina
    Piazza della Repubblica
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $30
  • Itabus
    9h 35m
    0
    10:15 PM
    Messina
    Piazza della Repubblica
    7:50 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $33
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $-5? You will find the corresponding connections below.
    • 9h 40m
      Messina
      8 mi
      3:50 AM
      Reggio Calabria
      Via Saracinello Al Torrente
      1:30 PM
      Rome
      Tiburtina Bus Station
      0 mi
      Economy
      $28
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $9? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $9

Cheapest bus trips Friday

Prices are for one way and one person
  • Itabus
    13h 50m
    0
    11:50 PM
    Messina
    Central Station
    1:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $21
  • Itabus
    13h 50m
    0
    11:50 PM
    Messina
    Piazza della Repubblica
    1:40 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $22
  • FlixBus
    9h 20m
    0
    10:50 PM
    Messina
    Piazza della Repubblica
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $33
  • FlixBus
    9h 35m
    0
    9:30 PM
    Messina
    Piazza della Repubblica
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $34
  • Autoservizi Salemi
    8h 55m
    0
    9:05 PM
    Messina
    Piazza della Repubblica
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $57
  • Did you know that if you travel from Messina to Rome via Reggio Calabria, you can save more than $0? You will find the corresponding connections below.
    • Save more than 1%
      10h 35m
      Messina
      8 mi
      7:20 PM
      Reggio Calabria
      Central Station
      5:55 AM
      Rome
      Tiburtina Bus Station
      0 mi
      Economy
      $21
  • Did you know that if you travel from Messina to Rome via Naples, you can save more than $7? You can find the corresponding connections below.
    • Distribusion
      11h 40m
      0
      10:15 PM
      Messina
      Central Station
      5:05 AM
      Naples
      Metropark Centrale
      0
      Distribusion
      Premium Economy
      $10
      • Waiting Time 2h 10m
    • Distribusion
      2h 40m
      0
      7:15 AM
      Naples
      Metropark Centrale
      9:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $4
    Travel time is 2h 45m longer, but you will save $7

Frequency of bus connections between Messina and Rome

See here how frequent the connections between Messina and Rome are, during different times and days of the week.
Friday is the busiest day, with more than 18 daily buses from Messina to Rome. Tuesday has instead the fewest connections, with only 3 daily coaches between Messina and Rome.
The busiest time of the day is the Evening, with 61 buses from Messina to Rome, while Afternoon sees the fewest connections between Messina and Rome, with 5 offers.

Facts about the bus from Messina to Rome

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 11 times every day by bus from Messina to Rome in one click! Book your bus ticket from Messina to Rome starting from $21!

Cheapest Bus $21
Fastest Bus 8h 55m
Earliest Bus 10:55 AM
Latest Bus 11:50 PM
Daily Bus Routes 11 Ø
Distance 303.0 miles
Bus Companies FlixBus, Itabus and Autoservizi Salemi

Cheapest bus connections from Messina to Rome

Every day, 11 buses from 3 bus companies leave Messina for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/16
Monday 03/17
Tuesday 03/18
Wednesday 03/19
Thursday 03/20
Friday 03/21
Saturday 03/22
$50
Sunday 03/23
$25
Monday 03/24
$21
Tuesday 03/25
$22
Wednesday 03/26
$54
Thursday 03/27
$39
Friday 03/28
$21
Saturday 03/29
$57
Sunday 03/30
$16
Monday 03/31
$34
Tuesday 04/01
$28
Wednesday 04/02
Thursday 04/03
$21
Friday 04/04
$28
Saturday 04/05
Sunday 04/06
$22
Monday 04/07
$17
Tuesday 04/08
$58
Wednesday 04/09
$58
Thursday 04/10
$11
Friday 04/11
$60
Saturday 04/12

The cheapest time to travel from Messina to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Messina to Rome, for the next 30 days.
With a price starting from $21, Monday is the cheapest day for a bus from Messina to Rome. Sunday instead is the most expensive day with prices starting from $24.
Evening is the cheapest day time for bus tickets from Messina to Rome, with $21. Morning is the most expensive time of the day with prices starting from $22.

How to save money travelling from Messina to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Messina to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Messina to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Messina to Rome are also emptier.

Beloved bus companies from Messina to Rome

These are the most booked bus companies between Messina to Rome from our users.

FlixBus from Messina to Rome

FlixBus

Here you will find the key facts about the FlixBus bus route Messina to Rome:

Cheapest Price $22
Fastest Bus 9h 20m
Earliest Bus 10:55 AM
Last Bus 10:50 PM
Daily Connections 4 Ø
Found on 3/22/2025

All bus stations and stops in Messina and Rome

In the map below, you can see where to find all bus stations in Messina and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Messina to Rome? Compare all modes of transports from Messina to Rome.

Service and Comfort on the bus from Messina to Rome

Want to know which seat classes are available on the buses from Messina to Rome? Or which bus companies serve the route Messina to Rome? Below you will find answers to your questions.

FAQs about the Messina to Rome bus

How much does a Messina Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 13h 50m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Messina to Rome?

This route is offered by 3 companies with a range of ticket prices between $21 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Messina to Rome each day?

Every day, the Messina to Rome bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Messina to Rome take?

The fastest bus from Messina to Rome is offered by Autoservizi Salemi and takes 8h 55m. Bus tickets for this connection cost $50. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Messina to Rome?

The earliest bus arriving in Rome from Messina starts at 10:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Messina to Rome?

The latest bus trip departing from Messina for Rome starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Messina Rome route?

When traveling by bus from Messina to Rome, passengers can travel with FlixBus, Itabus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Messina and Rome?

You can check all the direct connections between Messina and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the Messina to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Messina Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Messina Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Messina to Rome on your planned travel date.

Available seat classes which are offered on the bus route Messina to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Messina and to Rome

Here’s an overview of the most popular bus routes to Messina and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Taormina to Messina Buses Taormina to Messina
Bus from Palermo to Messina Bus from Palermo to Messina
Catania to Messina bus Catania to Messina bus
Bus Bari to Messina Bus Bari to Messina
Bus from Bologna to Rome Bus from Bologna to Rome
Buses to Rome from Zurich Buses to Rome from Zurich
Bus from Bari to Rome Bus from Bari to Rome
Buses to Rome from Barcelona Buses to Rome from Barcelona
Popular Airport Shuttles to Messina and to Rome
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