Bus from Mezcales to Mexico City from $97

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Compare all timetables for the bus from Mezcales to Mexico City

Here is a selection of the cheapest bus trips from the schedule from Mezcales to Mexico City from various bus operators like ETN Autobuses or Primera Plus for the next days.

today
from $100
tomorrow
from $100
Wednesday
from $100
Thursday
from $100
Friday
from $100
Saturday
from $100
Sunday
from $100

Cheapest bus trips today

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Premium Economy $142
ETN Autobuses 11h 40m 9:40 PM Mezcales Vallarte Plus 9:20 AM Mexico City Norte Bus Station  Premium Economy $142
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Basic $292
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Cheapest bus trips tomorrow

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Cheapest bus trips Wednesday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Premium Economy $147
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Cheapest bus trips Thursday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
ETN Autobuses 13h 0m 8:10 PM Mezcales Vallarte Plus 9:10 AM Mexico City Taxqueña Bus Station  Economy $131
ETN Autobuses 13h 0m 8:10 PM Mezcales Vallarte Plus 9:10 AM Mexico City Taxqueña Bus Station  Premium Economy $136
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Economy $139
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Cheapest bus trips Friday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Basic $141
ETN Autobuses 11h 40m 9:40 PM Mezcales Vallarte Plus 9:20 AM Mexico City Norte Bus Station  Basic $141
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Premium Economy $145
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Cheapest bus trips Saturday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Premium Economy $142
ETN Autobuses 11h 40m 9:40 PM Mezcales Vallarte Plus 9:20 AM Mexico City Norte Bus Station  Premium Economy $142
ETN Autobuses 11h 30m 5:40 PM Mezcales Vallarte Plus 5:10 AM Mexico City Norte Bus Station  Basic $147
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Cheapest bus trips Sunday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $100
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $100
ETN Autobuses 11h 30m 5:20 PM Mezcales Vallarte Plus 4:50 AM Mexico City Norte Bus Station  Basic $142
ETN Autobuses 11h 40m 9:20 PM Mezcales Vallarte Plus 9:00 AM Mexico City Norte Bus Station  Basic $142
ETN Autobuses 11h 30m 5:20 PM Mezcales Vallarte Plus 4:50 AM Mexico City Norte Bus Station  Premium Economy $145
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $21? You can find the corresponding connections below.
    • Primera Plus
      13h 15m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $46
      • Waiting Time 0h 40m
    • Busbud
      8h 5m
      0
      9:00 PM
      Guadalajara, JC
      Guadalupe
      5:05 AM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      0
      Busbud
      Economy
      $33
    Travel time is 3h 0m longer, but you will save $21

Best Price Offer: The price for the cheapest bus from Mezcales to Mexico City is $97 on 8/18/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Mezcales and Mexico City

See here how frequent the connections between Mezcales and Mexico City are, during different times and days of the week.
Thursday is the busiest day, with more than 8 daily buses from Mezcales to Mexico City. Tuesday has instead the fewest connections, with only 2 daily coaches between Mezcales and Mexico City.
The busiest time of the day is the Evening, with 23 buses from Mezcales to Mexico City, while Afternoon sees the fewest connections between Mezcales and Mexico City, with 11 offers.

Facts about the bus from Mezcales to Mexico City

Compare all providers like ETN Autobuses and Primera Plus that travel 4 times every day by bus from Mezcales to Mexico City in one click! Book your bus ticket from Mezcales to Mexico City starting from $97!

Cheapest Bus $97
Fastest Bus 10h 15m
Earliest Bus 5:40 PM
Latest Bus 9:30 PM
Daily Bus Routes 4 Ø
Distance 409.1 miles
Bus Companies ETN Autobuses and Primera Plus

Cheapest bus connections from Mezcales to Mexico City

Every day, 4 buses from 2 bus companies leave Mezcales for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/11/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/10
Monday 08/11
$101
Tuesday 08/12
$101
Wednesday 08/13
$101
Thursday 08/14
$101
Friday 08/15
$101
Saturday 08/16
$101
Sunday 08/17
$101
Monday 08/18
$97
Tuesday 08/19
$101
Wednesday 08/20
$101
Thursday 08/21
$101
Friday 08/22
$101
Saturday 08/23
$101
Sunday 08/24
$101
Monday 08/25
$101
Tuesday 08/26
$101
Wednesday 08/27
$101
Thursday 08/28
$101
Friday 08/29
$101
Saturday 08/30
$101
Sunday 08/31
$101
Monday 09/01
$101
Tuesday 09/02
$101
Wednesday 09/03
$101
Thursday 09/04
$101
Friday 09/05
$101
Saturday 09/06

The cheapest time to travel from Mezcales to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from Mezcales to Mexico City, for the next 30 days.
With a price starting from $97, Monday is the cheapest day for a bus from Mezcales to Mexico City. Sunday instead is the most expensive day with prices starting from $100.
Evening is the cheapest day time for bus tickets from Mezcales to Mexico City, with $100. Afternoon is the most expensive time of the day with prices starting from $139.

How to save money travelling from Mezcales to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mezcales to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mezcales to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mezcales to Mexico City are also emptier.

Beloved bus companies from Mezcales to Mexico City

These are the most booked bus companies between Mezcales to Mexico City from our users.

Primera Plus from Mezcales to Mexico City

Primera Plus

Here you will find the key facts about the Primera Plus bus route Mezcales to Mexico City:

Cheapest Price $100
Fastest Bus 10h 15m
Earliest Bus 8:30 PM
Last Bus 9:30 PM
Daily Connections 2 Ø
Found on 8/11/2025

All bus stations and stops in Mezcales and Mexico City

In the map below, you can see where to find all bus stations in Mezcales and Mexico City.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mezcales to Mexico City? Compare all modes of transports from Mezcales to Mexico City.

Service and Comfort on the bus from Mezcales to Mexico City

Want to know which seat classes are available on the buses from Mezcales to Mexico City? Or which bus companies serve the route Mezcales to Mexico City? Below you will find answers to your questions.

FAQs about the Mezcales to Mexico City bus

How much does a Mezcales Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $97 and takes 10h 20m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from Mezcales to Mexico City?

This route is offered by 2 companies with a range of ticket prices between $97 and $292. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from Mezcales to Mexico City each day?

Every day, the Mezcales to Mexico City bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mezcales to Mexico City take?

The fastest bus from Mezcales to Mexico City is offered by Primera Plus and takes 10h 15m. Bus tickets for this connection cost $100. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mezcales to Mexico City?

The earliest bus arriving in Mexico City from Mezcales starts at 5:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mezcales to Mexico City?

The latest bus trip departing from Mezcales for Mexico City starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mezcales Mexico City route?

When traveling by bus from Mezcales to Mexico City, passengers can travel with ETN Autobuses and Primera Plus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mezcales and Mexico City?

You can check all the direct connections between Mezcales and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses and Primera Plus.

What can I take with me on the Mezcales to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mezcales Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mezcales Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mezcales to Mexico City on your planned travel date.

Available seat classes which are offered on the bus route Mezcales to Mexico City

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mezcales and to Mexico City

Here’s an overview of the most popular bus routes to Mezcales and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Toluca, ME to Mezcales bus Toluca, ME to Mezcales bus
From León de los Aldama to Mezcales bus From León de los Aldama to Mezcales bus
Buses Oaxaca de Juárez - Mexico City Buses Oaxaca de Juárez - Mexico City
Bus from Puebla City, PL to Mexico City Bus from Puebla City, PL to Mexico City
Buses to Mexico City from Guanajuato Buses to Mexico City from Guanajuato
Bus to Mexico City from Taxco Bus to Mexico City from Taxco
Popular Airport Shuttles to Mezcales and to Mexico City
CheckMyBus › Buses in Mexico › Bus to Mezcales › Bus to Mexico City

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