Bus from Rome to Frankfurt am Main from $66

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Compare all timetables for the bus from Rome to Frankfurt am Main

Here is a selection of the cheapest bus trips from the schedule from Rome to Frankfurt am Main from various bus operators like FlixBus for the next days.
today
from $74
tomorrow
from $73
Friday
from $82
Saturday
from $77
Sunday
from $96
Monday
from $66
Tuesday
from $67

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    20h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    5:55 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    24h 25m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $77
  • FlixBus
    20h 55m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $80
  • FlixBus
    19h 45m
    0
    10:40 AM
    Rome
    Tiburtina Bus Station
    6:25 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $85
  • FlixBus
    22h 55m
    0
    11:50 PM
    Rome
    Tiburtina Bus Station
    10:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $87
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $20? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 1h 10m longer, but you will save $20

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    22h 50m
    0
    11:40 PM
    Rome
    Anagnina Bus Station
    10:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $73
  • FlixBus
    21h 50m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    10:55 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $78
  • FlixBus
    19h 45m
    0
    10:40 AM
    Rome
    Tiburtina Bus Station
    6:25 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $80
  • FlixBus
    20h 55m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $83
  • FlixBus
    20h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    5:55 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $86
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $19? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 1h 10m longer, but you will save $19

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    22h 50m
    0
    11:40 PM
    Rome
    Anagnina Bus Station
    10:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $82
  • FlixBus
    23h 45m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    7:15 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $84
  • FlixBus
    20h 55m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $87
  • FlixBus
    21h 45m
    0
    9:30 AM
    Rome
    Tiburtina Bus Station
    7:15 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $88
  • FlixBus
    20h 30m
    0
    9:20 AM
    Rome
    Tiburtina Bus Station
    5:50 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $89
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $28? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 0h 25m longer, but you will save $28

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    22h 50m
    0
    11:40 PM
    Rome
    Anagnina Bus Station
    10:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $77
  • FlixBus
    25h 30m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    10:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $83
  • FlixBus
    21h 55m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    2:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $85
  • FlixBus
    23h 55m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    7:25 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $85
  • FlixBus
    20h 45m
    0
    10:40 AM
    Rome
    Tiburtina Bus Station
    7:25 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $87
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $23? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 0h 10m longer, but you will save $23

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    21h 55m
    0
    8:30 AM
    Rome
    Anagnina Bus Station
    6:25 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    19h 45m
    0
    10:40 AM
    Rome
    Tiburtina Bus Station
    6:25 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $101
  • FlixBus
    21h 50m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    10:55 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $101
  • FlixBus
    21h 55m
    0
    1:00 PM
    Rome
    Tiburtina Bus Station
    10:55 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $106
  • FlixBus
    20h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    5:55 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $114
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $42? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is 1h 10m longer, but you will save $42

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    6:15 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    20h 55m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $71
  • FlixBus
    21h 0m
    0
    9:20 AM
    Rome
    Tiburtina Bus Station
    6:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $72
  • FlixBus
    23h 45m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    7:15 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $77
  • FlixBus
    22h 55m
    0
    11:50 PM
    Rome
    Tiburtina Bus Station
    10:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $81
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is the same as the direct connection, but you will save $12

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    20h 55m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $67
  • FlixBus
    24h 25m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    1:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $72
  • FlixBus
    22h 15m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    6:15 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $72
  • FlixBus
    25h 30m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    9:00 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    21h 50m
    0
    8:30 AM
    Rome
    Tiburtina Bus Station
    6:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $78
  • Did you know that if you travel from Rome to Frankfurt am Main via Stuttgart Airport, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      20h 55m
      0
      4:35 PM
      Rome
      Tiburtina Bus Station
      9:55 AM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $42
      • Waiting Time 0h 5m
    • FlixBus
      3h 30m
      0
      10:00 AM
      Stuttgart Airport
      Stuttgart Airport
      1:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $12
    Travel time is the same as the direct connection, but you will save $13

Frequency of bus connections between Rome and Frankfurt am Main

See here how frequent the connections between Rome and Frankfurt am Main are, during different times and days of the week.
Sunday is the busiest day, with more than 11 daily buses from Rome to Frankfurt am Main. Tuesday has instead the fewest connections, with only 6 daily coaches between Rome and Frankfurt am Main.
The busiest time of the day is the Afternoon, with 22 buses from Rome to Frankfurt am Main, while Night sees the fewest connections between Rome and Frankfurt am Main, with 5 offers.

Facts about the bus from Rome to Frankfurt am Main

Compare all providers like FlixBus that travel 9 times every day by bus from Rome to Frankfurt am Main in one click! Book your bus ticket from Rome to Frankfurt am Main starting from $66!

Cheapest Bus $66
Fastest Bus 19h 45m
Earliest Bus 8:30 AM
Latest Bus 11:50 PM
Daily Bus Routes 9 Ø
Distance 596.0 miles
Bus Companies FlixBus

Cheapest bus connections from Rome to Frankfurt am Main

Every day, 9 buses from 1 bus companies leave Rome for Frankfurt am Main: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/26/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/23
Monday 03/24
Tuesday 03/25
Wednesday 03/26
$74
Thursday 03/27
$73
Friday 03/28
$82
Saturday 03/29
$77
Sunday 03/30
$96
Monday 03/31
$66
Tuesday 04/01
$67
Wednesday 04/02
$67
Thursday 04/03
$66
Friday 04/04
$77
Saturday 04/05
$82
Sunday 04/06
$95
Monday 04/07
$73
Tuesday 04/08
$70
Wednesday 04/09
$65
Thursday 04/10
$70
Friday 04/11
$81
Saturday 04/12
$84
Sunday 04/13
$81
Monday 04/14
$81
Tuesday 04/15
$79
Wednesday 04/16
$82
Thursday 04/17
$88
Friday 04/18
$108
Saturday 04/19

The cheapest time to travel from Rome to Frankfurt am Main

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Frankfurt am Main, for the next 30 days.
With a price starting from $66, Monday is the cheapest day for a bus from Rome to Frankfurt am Main. Sunday instead is the most expensive day with prices starting from $96.
Evening is the cheapest day time for bus tickets from Rome to Frankfurt am Main, with $66. Night is the most expensive time of the day with prices starting from $97.

How to save money travelling from Rome to Frankfurt am Main

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Frankfurt am Main in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Frankfurt am Main, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Frankfurt am Main are also emptier.

Beloved bus companies from Rome to Frankfurt am Main

These are the most booked bus companies between Rome to Frankfurt am Main from our users.

FlixBus from Rome to Frankfurt am Main

FlixBus

Here you will find the key facts about the FlixBus bus route Rome to Frankfurt am Main:

Cheapest Price $66
Fastest Bus 19h 45m
Earliest Bus 8:30 AM
Last Bus 11:50 PM
Daily Connections 9 Ø
Found on 3/25/2025

All bus stations and stops in Rome and Frankfurt am Main

In the map below, you can see where to find all bus stations in Rome and Frankfurt am Main.

Service and Comfort on the bus from Rome to Frankfurt am Main

Want to know which seat classes are available on the buses from Rome to Frankfurt am Main? Or which bus companies serve the route Rome to Frankfurt am Main? Below you will find answers to your questions.

FAQs about the Rome to Frankfurt am Main bus

How much does a Rome Frankfurt am Main bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $66 and takes 22h 15m to reach Frankfurt am Main. Compare offers to save money!

How much could I save by comparing buses from Rome to Frankfurt am Main?

This route is offered by 1 companies with a range of ticket prices between $66 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frankfurt am Main.

On average, how many connections are available from Rome to Frankfurt am Main each day?

Every day, the Rome to Frankfurt am Main bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Frankfurt am Main take?

The fastest bus from Rome to Frankfurt am Main is offered by FlixBus and takes 19h 45m. Bus tickets for this connection cost $85. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Frankfurt am Main?

The earliest bus arriving in Frankfurt am Main from Rome starts at 8:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Frankfurt am Main?

The latest bus trip departing from Rome for Frankfurt am Main starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Frankfurt am Main route?

When traveling by bus from Rome to Frankfurt am Main, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Frankfurt am Main?

You can check all the direct connections between Rome and Frankfurt am Main by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Frankfurt am Main bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Frankfurt am Main bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Frankfurt am Main bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Frankfurt am Main on your planned travel date.

Available seat classes which are offered on the bus route Rome to Frankfurt am Main

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Frankfurt am Main

Here’s an overview of the most popular bus routes to Rome and to Frankfurt am Main. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Amalfi to Rome Buses from Amalfi to Rome
Buses to Rome from Assisi Buses to Rome from Assisi
Buses Milan to Rome Buses Milan to Rome
Bus from Pisa to Rome Bus from Pisa to Rome
Buses Kosice - Frankfurt am Main Buses Kosice - Frankfurt am Main
Bus to Frankfurt am Main from Hanover Bus to Frankfurt am Main from Hanover
Paris to Frankfurt am Main bus Paris to Frankfurt am Main bus
Bus to Frankfurt am Main from Rothenburg ob der Tauber Bus to Frankfurt am Main from Rothenburg ob der Tauber
Popular Airport Shuttles to Rome and to Frankfurt am Main
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