Compare all timetables for the bus from Rome to Isernia
Here is a selection of the cheapest bus trips from the schedule from Rome to Isernia from various bus operators like FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 10m | 2:50 PM | Rome | Tiburtina Bus Station | 5:00 PM | Isernia | Central Bus Station | Economy | $36 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 2:50:00 PM to Central Bus Station, Isernia (Italy) arriving at 12/21/2025 5:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 2h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 10m | 2:50 PM | Rome | Tiburtina Bus Station | 5:00 PM | Isernia | Central Bus Station | Economy | $42 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 2:50:00 PM to Central Bus Station, Isernia (Italy) arriving at 12/23/2025 5:00:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 2h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 10m | 2:50 PM | Rome | Tiburtina Bus Station | 5:00 PM | Isernia | Central Bus Station | Economy | $40 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 2:50:00 PM to Central Bus Station, Isernia (Italy) arriving at 12/24/2025 5:00:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 2h 10m
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Best Price Offer: The price for the cheapest bus from Rome to Isernia is $15 on 12/26/2025. Flexible travelers save on ticket prices.
Facts about the bus from Rome to Isernia
Compare all providers like FlixBus that travel 1 times every day by bus from Rome to Isernia in one click! Book your bus ticket from Rome to Isernia starting from $15!
| Cheapest Bus | $15 |
| Fastest Bus | 2h 10m |
| Earliest Bus | 2:50 PM |
| Latest Bus | 2:50 PM |
| Daily Bus Routes | 1 Ø |
| Distance | 91.9 miles |
| Bus Companies | FlixBus |
Cheapest bus connections from Rome to Isernia
Every day, 1 buses from 1 bus companies leave Rome for Isernia: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
$36
Monday
12/22
Tuesday
12/23
$42
Wednesday
12/24
$40
Thursday
12/25
Friday
12/26
$15
Saturday
12/27
Sunday
12/28
Monday
12/29
Tuesday
12/30
Wednesday
12/31
Thursday
01/01
Friday
01/02
Saturday
01/03
Sunday
01/04
Monday
01/05
Tuesday
01/06
Wednesday
01/07
Thursday
01/08
Friday
01/09
Saturday
01/10
How to save money travelling from Rome to Isernia
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Rome to Isernia in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Isernia, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Isernia are also emptier.All bus stations and stops in Rome and Isernia
In the map below, you can see where to find all bus stations in Rome and Isernia.
Compare the bus with other modes of transport
The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Isernia? Compare all modes of transports from
Rome to Isernia.
Service and Comfort on the bus from Rome to Isernia
Want to know which seat classes are available on the buses from Rome to Isernia? Or which bus companies serve the route Rome to Isernia? Below you will find answers to your questions.
FAQs about the Rome to Isernia bus
How much does a Rome Isernia bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $15 and takes 2h 10m to reach Isernia. Compare offers to save money!
How much could I save by comparing buses from Rome to Isernia?
This route is offered by 1 companies with a range of ticket prices between $15 and $42. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Isernia.
On average, how many connections are available from Rome to Isernia each day?
Every day, the Rome to Isernia bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Rome to Isernia take?
The fastest bus from Rome to Isernia is offered by FlixBus and takes 2h 10m. Bus tickets for this connection cost $36. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Rome to Isernia?
The earliest bus arriving in Isernia from Rome starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Rome to Isernia?
The latest bus trip departing from Rome for Isernia starts at 2:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Rome Isernia route?
When traveling by bus from Rome to Isernia, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Rome and Isernia?
You can check all the direct connections between Rome and Isernia by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.
What can I take with me on the Rome to Isernia bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Isernia bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Rome Isernia bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Isernia on your planned travel date.
How does CheckMyBus find the best bus deals from Rome to Isernia?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Rome and Isernia. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Rome to Isernia?
Prices and availability for 1 trips between Rome and Isernia change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Rome to Isernia
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Rome and to Isernia
Here’s an overview of the most popular bus routes to Rome and to Isernia. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Rome
- Arezzo to Rome bus
- Bus Ascoli Piceno - Rome
- Buses from Assisi to Rome
- From Civitavecchia to Rome bus
- From Lyon to Rome bus
- Bus from Matera to Rome
- Bus Mestre to Rome
- Bus Milan - Rome
- From Naples to Rome bus
- Buses Paris to Rome
- From Pescara to Rome bus
- Pisa to Rome bus
- Bus to Rome from Porto San Giorgio
- Bus to Rome from San Benedetto del Tronto
- Buses Siena to Rome
- Buses Sorrento - Rome
- Buses Termoli - Rome
- Bus to Rome from Venice
- From Vienna to Rome bus
- Buses to Rome from Villa Rosa
- Bus Routes to Isernia
- Bus to Isernia from Molfetta
- Montenero di Bisaccia to Isernia bus
- Bus to Isernia from Vasto
Popular Airport Shuttles to Rome and to Isernia
