Bus from Rome to Lyon from $51

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Compare all timetables for the bus from Rome to Lyon

Here is a selection of the cheapest bus trips from the schedule from Rome to Lyon from various bus operators like FlixBus, Itabus or BlaBlaCar Bus for the next days.
today
from $57
tomorrow
from $58
Monday
from $63
Tuesday
from $63
Wednesday
from $51
Thursday
from $57
Friday
from $63

Cheapest bus trips today

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $57
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Economy
    $66
  • BlaBlaCar Bus
    14h 40m
    0
    4:30 PM
    Rome
    Tiburtina Bus Station
    7:10 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $74
  • FlixBus
    16h 45m
    0
    4:00 PM
    Rome
    Tiburtina Bus Station
    8:45 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $98
  • FlixBus
    18h 55m
    0
    11:50 PM
    Rome
    Tiburtina Bus Station
    6:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $98
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $17? You can find the corresponding connections below.
    • BlaBlaCar Bus
      21h 35m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 0m
    • Distribusion
      4h 55m
      0
      8:00 AM
      Turin
      Stura Bus Station
      12:55 PM
      Lyon
      Perrache Bus Stop
      0
      Distribusion
      Premium Economy
      $24
    Travel time is 6h 55m longer, but you will save $17

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Economy
    $58
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $68
  • BlaBlaCar Bus
    14h 40m
    0
    4:30 PM
    Rome
    Tiburtina Bus Station
    7:10 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $74
  • FlixBus
    16h 45m
    0
    4:00 PM
    Rome
    Tiburtina Bus Station
    8:45 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $95
  • BlaBlaCar Bus
    14h 50m
    0
    3:20 PM
    Rome
    Tiburtina Bus Station
    6:10 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $102
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $18? You can find the corresponding connections below.
    • BlaBlaCar Bus
      21h 35m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 0m
    • Distribusion
      4h 55m
      0
      8:00 AM
      Turin
      Stura Bus Station
      12:55 PM
      Lyon
      Perrache Bus Stop
      0
      Distribusion
      Premium Economy
      $24
    Travel time is 6h 55m longer, but you will save $18

Cheapest bus trips Monday

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $63
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $63
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Economy
    $72
  • FlixBus
    16h 20m
    0
    9:55 PM
    Rome
    Tiburtina Bus Station
    2:15 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $110
  • FlixBus
    16h 15m
    0
    12:10 AM
    Rome
    Tiburtina Bus Station
    4:25 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $125
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $27? You can find the corresponding connections below.
    • BlaBlaCar Bus
      22h 40m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 30m
    • INFOBUS
      5h 30m
      0
      8:30 AM
      Turin
      Central Bus Station
      2:00 PM
      Lyon
      Perrache Bus Stop
      0
      INFOBUS
      Economy
      $21
    Travel time is 7h 30m longer, but you will save $27

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $63
  • Itabus
    14h 30m
    0
    7:00 AM
    Rome
    Tiburtina Bus Station
    9:30 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $68
  • FlixBus
    18h 55m
    0
    11:50 PM
    Rome
    Tiburtina Bus Station
    6:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $100
  • FlixBus
    16h 0m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    12:00 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $102
  • BlaBlaCar Bus
    14h 50m
    0
    3:20 PM
    Rome
    Tiburtina Bus Station
    6:10 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $125
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $23? You can find the corresponding connections below.
    • BlaBlaCar Bus
      21h 35m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 0m
    • Distribusion
      4h 55m
      0
      8:00 AM
      Turin
      Stura Bus Station
      12:55 PM
      Lyon
      Perrache Bus Stop
      0
      Distribusion
      Premium Economy
      $24
    Travel time is 7h 5m longer, but you will save $23

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $51
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $52
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Economy
    $57
  • FlixBus
    18h 30m
    0
    12:15 AM
    Rome
    Tiburtina Bus Station
    6:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $103
  • FlixBus
    14h 55m
    0
    5:50 PM
    Rome
    Tiburtina Bus Station
    8:45 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $106
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $11? You can find the corresponding connections below.
    • BlaBlaCar Bus
      21h 35m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 0m
    • Distribusion
      4h 55m
      0
      8:00 AM
      Turin
      Stura Bus Station
      12:55 PM
      Lyon
      Perrache Bus Stop
      0
      Distribusion
      Premium Economy
      $24
    Travel time is 6h 40m longer, but you will save $11

Cheapest bus trips Thursday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    7:00 AM
    Rome
    Tiburtina Bus Station
    9:30 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $57
  • FlixBus
    14h 55m
    0
    7:45 AM
    Rome
    Tiburtina Bus Station
    10:40 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $59
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $63
  • BlaBlaCar Bus
    14h 50m
    0
    3:20 PM
    Rome
    Tiburtina Bus Station
    6:10 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $74
  • FlixBus
    14h 55m
    0
    8:50 AM
    Rome
    Tiburtina Bus Station
    11:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $83
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $17? You can find the corresponding connections below.
    • BlaBlaCar Bus
      21h 35m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 0m
    • Distribusion
      4h 55m
      0
      8:00 AM
      Turin
      Stura Bus Station
      12:55 PM
      Lyon
      Perrache Bus Stop
      0
      Distribusion
      Premium Economy
      $24
    Travel time is 7h 5m longer, but you will save $17

Cheapest bus trips Friday

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $63
  • Itabus
    15h 10m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    12:55 PM
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    $63
  • FlixBus
    14h 55m
    0
    7:45 AM
    Rome
    Tiburtina Bus Station
    10:40 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $88
  • FlixBus
    14h 55m
    0
    8:50 AM
    Rome
    Tiburtina Bus Station
    11:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $88
  • BlaBlaCar Bus
    14h 50m
    0
    3:20 PM
    Rome
    Tiburtina Bus Station
    6:10 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $91
  • Did you know that if you travel from Rome to Lyon via Turin, you can save more than $23? You can find the corresponding connections below.
    • BlaBlaCar Bus
      21h 35m
      0
      3:20 PM
      Rome
      Tiburtina Bus Station
      1:00 AM
      Turin
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $16
      • Waiting Time 7h 0m
    • Distribusion
      4h 55m
      0
      8:00 AM
      Turin
      Stura Bus Station
      12:55 PM
      Lyon
      Perrache Bus Stop
      0
      Distribusion
      Premium Economy
      $24
    Travel time is 6h 45m longer, but you will save $23

Frequency of bus connections between Rome and Lyon

See here how frequent the connections between Rome and Lyon are, during different times and days of the week.
Sunday is the busiest day, with more than 22 daily buses from Rome to Lyon. Monday has instead the fewest connections, with only 16 daily coaches between Rome and Lyon.
The busiest time of the day is the Evening, with 62 buses from Rome to Lyon, while Night sees the fewest connections between Rome and Lyon, with 14 offers.

Facts about the bus from Rome to Lyon

Compare all providers like FlixBus, Itabus and BlaBlaCar Bus that travel 19 times every day by bus from Rome to Lyon in one click! Book your bus ticket from Rome to Lyon starting from $51!

Cheapest Bus $51
Fastest Bus 14h 30m
Earliest Bus 12:10 AM
Latest Bus 11:50 PM
Daily Bus Routes 19 Ø
Distance 465.5 miles
Bus Companies FlixBus, Itabus and BlaBlaCar Bus

Cheapest bus connections from Rome to Lyon

Every day, 19 buses from 3 bus companies leave Rome for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/13
Monday 04/14
Tuesday 04/15
Wednesday 04/16
Thursday 04/17
Friday 04/18
Saturday 04/19
$68
Sunday 04/20
$95
Monday 04/21
$110
Tuesday 04/22
$100
Wednesday 04/23
$103
Thursday 04/24
$57
Friday 04/25
$63
Saturday 04/26
$99
Sunday 04/27
$68
Monday 04/28
$68
Tuesday 04/29
$45
Wednesday 04/30
$68
Thursday 05/01
$68
Friday 05/02
$57
Saturday 05/03
$68
Sunday 05/04
$68
Monday 05/05
$57
Tuesday 05/06
$34
Wednesday 05/07
$34
Thursday 05/08
$51
Friday 05/09
$61
Saturday 05/10

The cheapest time to travel from Rome to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Lyon, for the next 30 days.
With a price starting from $51, Wednesday is the cheapest day for a bus from Rome to Lyon. Monday instead is the most expensive day with prices starting from $63.
Evening is the cheapest day time for bus tickets from Rome to Lyon, with $51. Night is the most expensive time of the day with prices starting from $103.

How to save money travelling from Rome to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Lyon are also emptier.

All bus stations and stops in Rome and Lyon

In the map below, you can see where to find all bus stations in Rome and Lyon.

Service and Comfort on the bus from Rome to Lyon

Want to know which seat classes are available on the buses from Rome to Lyon? Or which bus companies serve the route Rome to Lyon? Below you will find answers to your questions.

FAQs about the Rome to Lyon bus

How much does a Rome Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $51 and takes 15h 10m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Rome to Lyon?

This route is offered by 3 companies with a range of ticket prices between $51 and $182. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Rome to Lyon each day?

Every day, the Rome to Lyon bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Lyon take?

The fastest bus from Rome to Lyon is offered by Itabus and takes 14h 30m. Bus tickets for this connection cost $108. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Lyon?

The earliest bus arriving in Lyon from Rome starts at 12:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Lyon?

The latest bus trip departing from Rome for Lyon starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Lyon route?

When traveling by bus from Rome to Lyon, passengers can travel with FlixBus, Itabus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Lyon?

You can check all the direct connections between Rome and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and BlaBlaCar Bus.

What can I take with me on the Rome to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Lyon on your planned travel date.

Available seat classes which are offered on the bus route Rome to Lyon

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Lyon

Here’s an overview of the most popular bus routes to Rome and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus Caen - Lyon Bus Caen - Lyon
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Bus to Lyon from Clermont-Ferrand Bus to Lyon from Clermont-Ferrand
Buses Val-d'Isère - Lyon Buses Val-d'Isère - Lyon
Popular Airport Shuttles to Rome and to Lyon
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