Bus from Rome to Palermo from $22

Compare 2 companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Rome to Palermo

Here is a selection of the cheapest bus trips from the schedule from Rome to Palermo from various bus operators like FlixBus or Autoservizi Salemi for the next days.
today
from $48
tomorrow
from $22
Monday
from $43
Tuesday
from $42
Wednesday
from $52
Thursday
from $28
Friday
from $28

Cheapest bus trips today

Prices are for one way and one person
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $48
  • FlixBus
    19h 15m
    0
    9:40 PM
    Rome
    Anagnina Bus Station
    4:55 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $52
  • FlixBus
    14h 55m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $57
  • FlixBus
    21h 0m
    0
    5:25 PM
    Rome
    Anagnina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $58
  • Did you know that if you travel from Rome to Palermo via Caserta, you can save more than $15? You can find the corresponding connections below.
    • FlixBus
      16h 45m
      0
      9:40 PM
      Rome
      Anagnina Bus Station
      11:50 PM
      Caserta
      Train Station
      0
      FlixBus
      Economy
      $11
      • Waiting Time 3h 40m
    • FlixBus
      10h 55m
      0
      3:30 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      2:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel time is 5h 0m longer, but you will save $15

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $22
  • FlixBus
    13h 10m
    0
    1:15 AM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $48
  • FlixBus
    14h 55m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $60
  • FlixBus
    14h 45m
    0
    8:15 PM
    Rome
    Tiburtina Bus Station
    11:00 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $77

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    1:15 AM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $43
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $52
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $54
  • FlixBus
    14h 55m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $70
  • FlixBus
    14h 45m
    0
    8:15 PM
    Rome
    Tiburtina Bus Station
    11:00 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $96
  • Did you know that if you travel from Rome to Palermo via Caserta, you can save more than $10? You can find the corresponding connections below.
    • FlixBus
      16h 45m
      0
      9:40 PM
      Rome
      Anagnina Bus Station
      11:50 PM
      Caserta
      Train Station
      0
      FlixBus
      Economy
      $11
      • Waiting Time 3h 40m
    • FlixBus
      10h 55m
      0
      3:30 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      2:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel time is 5h 0m longer, but you will save $10

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    1:15 AM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $42
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $54
  • FlixBus
    14h 55m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $81
  • Did you know that if you travel from Rome to Palermo via Caserta, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      16h 45m
      0
      9:40 PM
      Rome
      Anagnina Bus Station
      11:50 PM
      Caserta
      Train Station
      0
      FlixBus
      Economy
      $11
      • Waiting Time 3h 40m
    • FlixBus
      10h 55m
      0
      3:30 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      2:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel time is 5h 0m longer, but you will save $9

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    1:15 AM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $52
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $63
  • FlixBus
    17h 25m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    4:55 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $66
  • Did you know that if you travel from Rome to Palermo via Caserta, you can save more than $19? You can find the corresponding connections below.
    • FlixBus
      16h 45m
      0
      9:40 PM
      Rome
      Anagnina Bus Station
      11:50 PM
      Caserta
      Train Station
      0
      FlixBus
      Economy
      $11
      • Waiting Time 3h 40m
    • FlixBus
      10h 55m
      0
      3:30 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      2:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel time is 5h 0m longer, but you will save $19

Cheapest bus trips Thursday

Prices are for one way and one person
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $28
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $56
  • FlixBus
    19h 30m
    0
    3:30 PM
    Rome
    Tiburtina Bus Station
    11:00 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $58
  • FlixBus
    17h 25m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    4:55 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $68
  • FlixBus
    14h 45m
    0
    8:15 PM
    Rome
    Tiburtina Bus Station
    11:00 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $70

Cheapest bus trips Friday

Prices are for one way and one person
  • Autoservizi Salemi
    11h 45m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    7:45 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    $28
  • FlixBus
    19h 30m
    0
    3:30 PM
    Rome
    Tiburtina Bus Station
    11:00 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $34
  • FlixBus
    14h 55m
    0
    11:30 PM
    Rome
    Tiburtina Bus Station
    2:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $37
  • FlixBus
    19h 15m
    0
    9:40 PM
    Rome
    Anagnina Bus Station
    4:55 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    $42

Frequency of bus connections between Rome and Palermo

See here how frequent the connections between Rome and Palermo are, during different times and days of the week.
Saturday is the busiest day, with more than 6 daily buses from Rome to Palermo. Tuesday has instead the fewest connections, with only 3 daily coaches between Rome and Palermo.
The busiest time of the day is the Evening, with 23 buses from Rome to Palermo, while Afternoon sees the fewest connections between Rome and Palermo, with 4 offers.

Facts about the bus from Rome to Palermo

Compare all providers like FlixBus and Autoservizi Salemi that travel 4 times every day by bus from Rome to Palermo in one click! Book your bus ticket from Rome to Palermo starting from $22!

Cheapest Bus $22
Fastest Bus 11h 45m
Earliest Bus 3:30 PM
Latest Bus 11:30 PM
Daily Bus Routes 4 Ø
Distance 265.6 miles
Bus Companies FlixBus and Autoservizi Salemi

Cheapest bus connections from Rome to Palermo

Every day, 4 buses from 2 bus companies leave Rome for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/16
Monday 03/17
Tuesday 03/18
Wednesday 03/19
Thursday 03/20
Friday 03/21
Saturday 03/22
$52
Sunday 03/23
$48
Monday 03/24
$43
Tuesday 03/25
$42
Wednesday 03/26
$52
Thursday 03/27
$58
Friday 03/28
$34
Saturday 03/29
$54
Sunday 03/30
$26
Monday 03/31
$43
Tuesday 04/01
$37
Wednesday 04/02
$39
Thursday 04/03
$37
Friday 04/04
$31
Saturday 04/05
$27
Sunday 04/06
$54
Monday 04/07
$38
Tuesday 04/08
$36
Wednesday 04/09
$31
Thursday 04/10
$39
Friday 04/11
$30
Saturday 04/12

The cheapest time to travel from Rome to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Palermo, for the next 30 days.
With a price starting from $22, Sunday is the cheapest day for a bus from Rome to Palermo. Wednesday instead is the most expensive day with prices starting from $52.
Evening is the cheapest day time for bus tickets from Rome to Palermo, with $22. Night is the most expensive time of the day with prices starting from $42.

How to save money travelling from Rome to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Palermo are also emptier.

Beloved bus companies from Rome to Palermo

These are the most booked bus companies between Rome to Palermo from our users.

Autoservizi Salemi from Rome to Palermo

Autoservizi Salemi

Here you will find the key facts about the Autoservizi Salemi bus route Rome to Palermo:

Cheapest Price $22
Fastest Bus 11h 45m
Earliest Bus 8:00 PM
Last Bus 8:00 PM
Daily Connections 1 Ø
Found on 3/19/2025

All bus stations and stops in Rome and Palermo

In the map below, you can see where to find all bus stations in Rome and Palermo.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Palermo? Compare all modes of transports from Rome to Palermo.

Service and Comfort on the bus from Rome to Palermo

Want to know which seat classes are available on the buses from Rome to Palermo? Or which bus companies serve the route Rome to Palermo? Below you will find answers to your questions.

FAQs about the Rome to Palermo bus

How much does a Rome Palermo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 11h 45m to reach Palermo. Compare offers to save money!

How much could I save by comparing buses from Rome to Palermo?

This route is offered by 2 companies with a range of ticket prices between $22 and $96. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Palermo.

On average, how many connections are available from Rome to Palermo each day?

Every day, the Rome to Palermo bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Palermo take?

The fastest bus from Rome to Palermo is offered by Autoservizi Salemi and takes 11h 45m. Bus tickets for this connection cost $48. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Palermo?

The earliest bus arriving in Palermo from Rome starts at 3:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Palermo?

The latest bus trip departing from Rome for Palermo starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Palermo route?

When traveling by bus from Rome to Palermo, passengers can travel with FlixBus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Palermo?

You can check all the direct connections between Rome and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the Rome to Palermo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Palermo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Palermo on your planned travel date.

Available seat classes which are offered on the bus route Rome to Palermo

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Palermo

Here’s an overview of the most popular bus routes to Rome and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Florence - Rome Buses Florence - Rome
Buses Naples - Rome Buses Naples - Rome
Buses Venice to Rome Buses Venice to Rome
Sorrento to Rome bus Sorrento to Rome bus
Bus Marsala to Palermo Bus Marsala to Palermo
Buses to Palermo from Modica Buses to Palermo from Modica
Buses Messina - Palermo Buses Messina - Palermo
Buses Vittoria to Palermo Buses Vittoria to Palermo
Popular Airport Shuttles to Rome and to Palermo
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Palermo

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.