Bus from Santa Cruz de la Sierra to São Paulo from $131

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Compare all timetables for the bus from Santa Cruz de la Sierra to São Paulo

Here is a selection of the cheapest bus trips from the schedule from Santa Cruz de la Sierra to São Paulo from various bus operators like La Preferida Bus for the next days.
today
from $141
tomorrow
from $131
Wednesday
Thursday
from $141
Friday
from $131
Saturday
Sunday
from $131

Cheapest bus trips today

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Praça do Patriarca
    0
    La Preferida Bus
    First Class
    $141

Cheapest bus trips tomorrow

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Tietê Bus Station
    0
    La Preferida Bus
    First Class
    $131
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Praça do Patriarca
    0
    La Preferida Bus
    First Class
    $195

Cheapest bus trips Thursday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Praça do Patriarca
    0
    La Preferida Bus
    First Class
    $141
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Tietê Bus Station
    0
    La Preferida Bus
    First Class
    $182

Cheapest bus trips Friday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Tietê Bus Station
    0
    La Preferida Bus
    First Class
    $131

Cheapest bus trips Sunday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Tietê Bus Station
    0
    La Preferida Bus
    First Class
    $131
  • La Preferida Bus
    38h 0m
    0
    8:30 PM
    Santa Cruz de la Sierra
    Terminal Bimodal
    10:30 AM
    São Paulo
    Praça do Patriarca
    0
    La Preferida Bus
    First Class
    $195

Facts about the bus from Santa Cruz de la Sierra to São Paulo

Compare all providers like La Preferida Bus that travel 1 times every day by bus from Santa Cruz de la Sierra to São Paulo in one click! Book your bus ticket from Santa Cruz de la Sierra to São Paulo starting from $131!

Cheapest Bus $131
Fastest Bus 38h 0m
Earliest Bus 8:30 PM
Latest Bus 8:30 PM
Daily Bus Routes 1 Ø
Distance 1,140.8 miles
Bus Companies La Preferida Bus

Cheapest bus connections from Santa Cruz de la Sierra to São Paulo

Every day, 1 buses from 1 bus companies leave Santa Cruz de la Sierra for São Paulo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/28/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/27
Monday 04/28
$141
Tuesday 04/29
$195
Wednesday 04/30
Thursday 05/01
$182
Friday 05/02
$131
Saturday 05/03
Sunday 05/04
$195
Monday 05/05
Tuesday 05/06
$182
Wednesday 05/07
$141
Thursday 05/08
Friday 05/09
$138
Saturday 05/10
Sunday 05/11
Monday 05/12
$131
Tuesday 05/13
Wednesday 05/14
$131
Thursday 05/15
Friday 05/16
$182
Saturday 05/17
Sunday 05/18
$182
Monday 05/19
Tuesday 05/20
$182
Wednesday 05/21
Thursday 05/22
Friday 05/23
Saturday 05/24

How to save money travelling from Santa Cruz de la Sierra to São Paulo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Cruz de la Sierra to São Paulo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Cruz de la Sierra to São Paulo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Cruz de la Sierra to São Paulo are also emptier.

Beloved bus companies from Santa Cruz de la Sierra to São Paulo

These are the most booked bus companies between Santa Cruz de la Sierra to São Paulo from our users.

La Preferida Bus from Santa Cruz de la Sierra to São Paulo

La Preferida Bus

Here you will find the key facts about the La Preferida Bus bus route Santa Cruz de la Sierra to São Paulo:

Cheapest Price $131
Fastest Bus 38h 0m
Earliest Bus 8:30 PM
Last Bus 8:30 PM
Daily Connections 1 Ø
Found on 4/26/2025

All bus stations and stops in Santa Cruz de la Sierra and São Paulo

In the map below, you can see where to find all bus stations in Santa Cruz de la Sierra and São Paulo.

Service and Comfort on the bus from Santa Cruz de la Sierra to São Paulo

Want to know which seat classes are available on the buses from Santa Cruz de la Sierra to São Paulo? Or which bus companies serve the route Santa Cruz de la Sierra to São Paulo? Below you will find answers to your questions.

FAQs about the Santa Cruz de la Sierra to São Paulo bus

How much does a Santa Cruz de la Sierra São Paulo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $131 and takes 38h 0m to reach São Paulo. Compare offers to save money!

How much could I save by comparing buses from Santa Cruz de la Sierra to São Paulo?

This route is offered by 1 companies with a range of ticket prices between $131 and $195. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to São Paulo.

On average, how many connections are available from Santa Cruz de la Sierra to São Paulo each day?

Every day, the Santa Cruz de la Sierra to São Paulo bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Cruz de la Sierra to São Paulo take?

The fastest bus from Santa Cruz de la Sierra to São Paulo is offered by La Preferida Bus and takes 38h 0m. Bus tickets for this connection cost $141. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Cruz de la Sierra to São Paulo?

The earliest bus arriving in São Paulo from Santa Cruz de la Sierra starts at 8:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Cruz de la Sierra to São Paulo?

The latest bus trip departing from Santa Cruz de la Sierra for São Paulo starts at 8:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Cruz de la Sierra São Paulo route?

When traveling by bus from Santa Cruz de la Sierra to São Paulo, passengers can travel with La Preferida Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Cruz de la Sierra and São Paulo?

You can check all the direct connections between Santa Cruz de la Sierra and São Paulo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: La Preferida Bus.

What can I take with me on the Santa Cruz de la Sierra to São Paulo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Cruz de la Sierra São Paulo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Cruz de la Sierra São Paulo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Cruz de la Sierra to São Paulo on your planned travel date.

Available seat classes which are offered on the bus route Santa Cruz de la Sierra to São Paulo

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santa Cruz de la Sierra and to São Paulo

Here’s an overview of the most popular bus routes to Santa Cruz de la Sierra and to São Paulo. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Asunción, PY to Santa Cruz de la Sierra bus From Asunción, PY to Santa Cruz de la Sierra bus
Buses Sucre - Santa Cruz de la Sierra Buses Sucre - Santa Cruz de la Sierra
Buses La Paz - Santa Cruz de la Sierra Buses La Paz - Santa Cruz de la Sierra
Buses Cochabamba - Santa Cruz de la Sierra Buses Cochabamba - Santa Cruz de la Sierra
Buses from Porto Alegre, RS to São Paulo Buses from Porto Alegre, RS to São Paulo
Buses from Londrina, PR to São Paulo Buses from Londrina, PR to São Paulo
Bus from Itu to São Paulo Bus from Itu to São Paulo
Bus Santiago, RM - São Paulo Bus Santiago, RM - São Paulo
Popular Airport Shuttles to Santa Cruz de la Sierra and to São Paulo
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