Bus Santiago del Estero to Mendoza: Compare prices and save money

Compare all timetables for the bus from Santiago del Estero to Mendoza

Here is a selection of the cheapest bus trips from the schedule from Santiago del Estero to Mendoza from various bus operators like Andesmar or San Juan Mar del Plata for the next days.

today

$74

tomorrow

$73

Tuesday

$73

Wednesday

$73

Thursday

$73

Friday

Saturday

$73

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Andesmar	16h 23m	4:15 PM	Santiago del Estero	Central Bus Station	8:38 AM	Mendoza	Bus Station		Basic	$74	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 12/14/2025 4:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/15/2025 8:38:00 AM. 50 Basic ticket for $74 per person are available. Travel duration is 16h 23m

Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $12? You can find the corresponding connections below.
- Central de Pasajes
  
  16h 50m
  
  0
  
  6:40 PM
  
  Santiago del Estero
  Central Bus Station
  
  8:55 PM
  
  San Miguel de Tucumán
  Bus Station
  
  0
  
  Basic
  
  $10
  
  A Bus from Central de Pasajes goes from Central Bus Station, Santiago del Estero (Argentina) at 12/15/2025 6:40:00 PM to Bus Station, San Miguel de Tucumán (Argentina) arriving at 12/15/2025 8:55:00 PM. 50 Basic ticket for $10 per person are available. Travel duration is 2h 15m
- Voyenbus
  
  14h 0m
  
  0
  
  9:30 PM
  
  San Miguel de Tucumán
  Bus Station
  
  11:30 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $53
  
  A Bus from Voyenbus goes from Bus Station, San Miguel de Tucumán (Argentina) at 12/15/2025 9:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/16/2025 11:30:00 AM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 14h 0m
Travel time is 0h 27m longer, but you will save $12

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station		Premium Economy	$73	A Bus from San Juan Mar del Plata goes from Central Bus Station, Santiago del Estero (Argentina) at 12/15/2025 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/15/2025 5:40:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 17h 20m
	Andesmar	16h 23m	4:15 PM	Santiago del Estero	Central Bus Station	8:38 AM	Mendoza	Bus Station		Premium Economy	$74	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 12/15/2025 4:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/16/2025 8:38:00 AM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 16h 23m

Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $11? You can find the corresponding connections below.
- Central de Pasajes
  
  16h 50m
  
  0
  
  6:40 PM
  
  Santiago del Estero
  Central Bus Station
  
  8:55 PM
  
  San Miguel de Tucumán
  Bus Station
  
  0
  
  Basic
  
  $10
  
  A Bus from Central de Pasajes goes from Central Bus Station, Santiago del Estero (Argentina) at 12/15/2025 6:40:00 PM to Bus Station, San Miguel de Tucumán (Argentina) arriving at 12/15/2025 8:55:00 PM. 50 Basic ticket for $10 per person are available. Travel duration is 2h 15m
- Voyenbus
  
  14h 0m
  
  0
  
  9:30 PM
  
  San Miguel de Tucumán
  Bus Station
  
  11:30 AM
  
  Mendoza
  Bus Station
  
  0
  
  Premium Economy
  
  $53
  
  A Bus from Voyenbus goes from Bus Station, San Miguel de Tucumán (Argentina) at 12/15/2025 9:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/16/2025 11:30:00 AM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 14h 0m
Travel time is 0h 27m longer, but you will save $11

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station		Premium Economy	$73	A Bus from San Juan Mar del Plata goes from Central Bus Station, Santiago del Estero (Argentina) at 12/16/2025 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/16/2025 5:40:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 17h 20m
	Andesmar	16h 23m	4:15 PM	Santiago del Estero	Central Bus Station	8:38 AM	Mendoza	Bus Station		Premium Economy	$74	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 12/16/2025 4:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/17/2025 8:38:00 AM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 16h 23m

Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $21? You can find the corresponding connections below.
- Central de Pasajes
  
  15h 30m
  
  0
  
  12:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  2:50 AM
  
  San Miguel de Tucumán
  Bus Station
  
  0
  
  Premium Economy
  
  $18
  
  A Bus from Central de Pasajes goes from Central Bus Station, Santiago del Estero (Argentina) at 12/18/2025 12:30:00 AM to Bus Station, San Miguel de Tucumán (Argentina) arriving at 12/18/2025 2:50:00 AM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 20m
- Plataforma 10
  
  12h 15m
  
  0
  
  3:45 AM
  
  San Miguel de Tucumán
  Bus Station
  
  4:00 PM
  
  Mendoza
  Bus Station
  
  0
  
  First Class
  
  $34
  
  A Bus from Plataforma 10 goes from Bus Station, San Miguel de Tucumán (Argentina) at 12/18/2025 3:45:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 4:00:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 12h 15m
Travel Time is 0h 53m shorter, and you will save $21

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station		Premium Economy	$73	A Bus from San Juan Mar del Plata goes from Central Bus Station, Santiago del Estero (Argentina) at 12/17/2025 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/17/2025 5:40:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 17h 20m
	Andesmar	16h 23m	4:15 PM	Santiago del Estero	Central Bus Station	8:38 AM	Mendoza	Bus Station		Premium Economy	$74	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 12/17/2025 4:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 8:38:00 AM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 16h 23m

Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $21? You can find the corresponding connections below.
- Central de Pasajes
  
  15h 30m
  
  0
  
  12:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  2:50 AM
  
  San Miguel de Tucumán
  Bus Station
  
  0
  
  Premium Economy
  
  $18
  
  A Bus from Central de Pasajes goes from Central Bus Station, Santiago del Estero (Argentina) at 12/18/2025 12:30:00 AM to Bus Station, San Miguel de Tucumán (Argentina) arriving at 12/18/2025 2:50:00 AM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 20m
- Plataforma 10
  
  12h 15m
  
  0
  
  3:45 AM
  
  San Miguel de Tucumán
  Bus Station
  
  4:00 PM
  
  Mendoza
  Bus Station
  
  0
  
  First Class
  
  $34
  
  A Bus from Plataforma 10 goes from Bus Station, San Miguel de Tucumán (Argentina) at 12/18/2025 3:45:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 4:00:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 12h 15m
Travel Time is 0h 53m shorter, and you will save $21

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station		Premium Economy	$73	A Bus from San Juan Mar del Plata goes from Central Bus Station, Santiago del Estero (Argentina) at 12/18/2025 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 5:40:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 17h 20m
	Andesmar	16h 23m	4:15 PM	Santiago del Estero	Central Bus Station	8:38 AM	Mendoza	Bus Station		Premium Economy	$74	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 12/18/2025 4:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/19/2025 8:38:00 AM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 16h 23m

Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $21? You can find the corresponding connections below.
- Central de Pasajes
  
  15h 30m
  
  0
  
  12:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  2:50 AM
  
  San Miguel de Tucumán
  Bus Station
  
  0
  
  Premium Economy
  
  $18
  
  A Bus from Central de Pasajes goes from Central Bus Station, Santiago del Estero (Argentina) at 12/18/2025 12:30:00 AM to Bus Station, San Miguel de Tucumán (Argentina) arriving at 12/18/2025 2:50:00 AM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 20m
- Plataforma 10
  
  12h 15m
  
  0
  
  3:45 AM
  
  San Miguel de Tucumán
  Bus Station
  
  4:00 PM
  
  Mendoza
  Bus Station
  
  0
  
  First Class
  
  $34
  
  A Bus from Plataforma 10 goes from Bus Station, San Miguel de Tucumán (Argentina) at 12/18/2025 3:45:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 4:00:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 12h 15m
Travel Time is 0h 53m shorter, and you will save $21

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 20m	12:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Mendoza	Bus Station		Premium Economy	$73	A Bus from San Juan Mar del Plata goes from Central Bus Station, Santiago del Estero (Argentina) at 12/20/2025 12:20:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/20/2025 5:40:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 17h 20m
	Andesmar	16h 23m	4:15 PM	Santiago del Estero	Central Bus Station	8:38 AM	Mendoza	Bus Station		Premium Economy	$74	A Bus from Andesmar goes from Central Bus Station, Santiago del Estero (Argentina) at 12/20/2025 4:15:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/21/2025 8:38:00 AM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 16h 23m

Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $21? You can find the corresponding connections below.
- Central de Pasajes
  
  15h 30m
  
  0
  
  12:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  2:50 AM
  
  San Miguel de Tucumán
  Bus Station
  
  0
  
  Premium Economy
  
  $18
  
  A Bus from Central de Pasajes goes from Central Bus Station, Santiago del Estero (Argentina) at 12/18/2025 12:30:00 AM to Bus Station, San Miguel de Tucumán (Argentina) arriving at 12/18/2025 2:50:00 AM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 20m
- Plataforma 10
  
  12h 15m
  
  0
  
  3:45 AM
  
  San Miguel de Tucumán
  Bus Station
  
  4:00 PM
  
  Mendoza
  Bus Station
  
  0
  
  First Class
  
  $34
  
  A Bus from Plataforma 10 goes from Bus Station, San Miguel de Tucumán (Argentina) at 12/18/2025 3:45:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 4:00:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 12h 15m
Travel Time is 0h 53m shorter, and you will save $21

Best Price Offer: The price for the cheapest bus from Santiago del Estero to Mendoza is $73 on 12/14/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago del Estero and Mendoza

See here how frequent the connections between Santiago del Estero and Mendoza are, during different times and days of the week.

Tuesday is the busiest day, with more than 8 daily buses from Santiago del Estero to Mendoza. Sunday has instead the fewest connections, with only 5 daily coaches between Santiago del Estero and Mendoza.

The busiest time of the day is the Afternoon, with 24 buses from Santiago del Estero to Mendoza, while Night sees the fewest connections between Santiago del Estero and Mendoza, with 19 offers.

Facts about the bus from Santiago del Estero to Mendoza

Compare all providers like Andesmar and San Juan Mar del Plata that travel 7 times every day by bus from Santiago del Estero to Mendoza in one click! Book your bus ticket from Santiago del Estero to Mendoza starting from $73!

Cheapest Bus	$73
Fastest Bus	16h 23m
Earliest Bus	4:15 PM
Latest Bus	4:15 PM
Daily Bus Routes	7 Ø
Distance	445.5 miles
Bus Companies	Andesmar and San Juan Mar del Plata

Cheapest bus connections from Santiago del Estero to Mendoza

Every day, 7 buses from 2 bus companies leave Santiago del Estero for Mendoza: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/14/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

$73

Monday 12/15

$73

Tuesday 12/16

$73

Wednesday 12/17

$73

Thursday 12/18

$73

Friday 12/19

Saturday 12/20

$73

Sunday 12/21

$73

Monday 12/22

$73

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

$74

Friday 12/26

Saturday 12/27

Sunday 12/28

$73

Monday 12/29

Tuesday 12/30

$73

Wednesday 12/31

Thursday 01/01

Friday 01/02

$73

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Santiago del Estero to Mendoza

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago del Estero to Mendoza, for the next 30 days.

With a price starting from $73, Monday is the cheapest day for a bus from Santiago del Estero to Mendoza. Sunday instead is the most expensive day with prices starting from $73.

Night is the cheapest day time for bus tickets from Santiago del Estero to Mendoza, with $73. Afternoon is the most expensive time of the day with prices starting from $74.

How to save money travelling from Santiago del Estero to Mendoza

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago del Estero to Mendoza in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago del Estero to Mendoza, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago del Estero to Mendoza are also emptier.

All bus stations and stops in Santiago del Estero and Mendoza

In the map below, you can see where to find all bus stations in Santiago del Estero and Mendoza.

Central Bus Station

Av. Roca Norte 100

Av. Libertad & Av. Aguirre

Ambargasta

El Saladillo

Regional Hospital "Dr. Ramón Carrillo"

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel Hyatt

Chile 1124

Hotel NH Cordillera

1324 1324

Casa Juri

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago del Estero to Mendoza? Compare all modes of transports from Santiago del Estero to Mendoza.

Service and Comfort on the bus from Santiago del Estero to Mendoza

Want to know which seat classes are available on the buses from Santiago del Estero to Mendoza? Or which bus companies serve the route Santiago del Estero to Mendoza? Below you will find answers to your questions.

FAQs about the Santiago del Estero to Mendoza bus

How much does a Santiago del Estero Mendoza bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $73 and takes 17h 20m to reach Mendoza. Compare offers to save money!

How much could I save by comparing buses from Santiago del Estero to Mendoza?

This route is offered by 2 companies with a range of ticket prices between $73 and $89. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mendoza.

On average, how many connections are available from Santiago del Estero to Mendoza each day?

Every day, the Santiago del Estero to Mendoza bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago del Estero to Mendoza take?

The fastest bus from Santiago del Estero to Mendoza is offered by Andesmar and takes 16h 23m. Bus tickets for this connection cost $89. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago del Estero to Mendoza?

The earliest bus arriving in Mendoza from Santiago del Estero starts at 4:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago del Estero to Mendoza?

The latest bus trip departing from Santiago del Estero for Mendoza starts at 4:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago del Estero Mendoza route?

When traveling by bus from Santiago del Estero to Mendoza, passengers can travel with Andesmar and San Juan Mar del Plata. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago del Estero and Mendoza?

You can check all the direct connections between Santiago del Estero and Mendoza by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Andesmar and San Juan Mar del Plata.

What can I take with me on the Santiago del Estero to Mendoza bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago del Estero Mendoza bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago del Estero Mendoza bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago del Estero to Mendoza on your planned travel date.

Available seat classes which are offered on the bus route Santiago del Estero to Mendoza

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santiago del Estero and to Mendoza

Here’s an overview of the most popular bus routes to Santiago del Estero and to Mendoza. Simply click on the connection of your choice, and you will find all the details about your bus route!