Bus from Santiago, RM to Antofagasta from $24

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Compare all timetables for the bus from Santiago, RM to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Antofagasta from various bus operators like Cikbus Elité, Pullman San Andres or Pluss Chile for the next days.
today
from $24
tomorrow
from $31
Monday
from $24
Tuesday
from $31
Wednesday
from $24
Thursday
from $27
Friday
from $24

Cheapest bus trips today

Prices are for one way and one person
  • Cikbus Elité
    19h 5m
    0
    1:30 PM
    Santiago, RM
    Terminal San Borja
    8:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $24
  • Turbus
    17h 25m
    0
    1:50 PM
    Santiago, RM
    Terminal Alameda
    7:15 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $27
  • Nueva Andimar Vip
    19h 0m
    0
    7:50 AM
    Santiago, RM
    Sur Bus Station
    2:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman Bus
    18h 50m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    5:50 AM
    Antofagasta
    Terminal Buses Camus
    0
    Pullman Bus
    First Class
    $37
  • Pullman San Andres
    18h 30m
    0
    2:00 PM
    Santiago, RM
    Terminal San Borja
    8:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $37

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Cikbus Elité
    18h 15m
    0
    9:30 AM
    Santiago, RM
    Sur Bus Station
    3:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $31
  • Turbus
    18h 10m
    0
    8:30 AM
    Santiago, RM
    Terminal Alameda
    2:40 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $32
  • Nueva Andimar Vip
    19h 0m
    0
    7:50 AM
    Santiago, RM
    Sur Bus Station
    2:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman Bus
    18h 50m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    5:50 AM
    Antofagasta
    Terminal Buses Camus
    0
    Pullman Bus
    First Class
    $37
  • Pullman San Andres
    18h 0m
    0
    12:30 PM
    Santiago, RM
    Terminal San Borja
    6:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $37
  • Did you know that if you travel from Santiago, RM to Antofagasta via La Serena, you can save more than $5? You can find the corresponding connections below.
    • Recorrido CL
      18h 25m
      0
      10:30 AM
      Santiago, RM
      Sur Bus Station
      5:00 PM
      La Serena
      Bus Station
      0
      Recorrido CL
      Premium Economy
      $8
      • Waiting Time 0h 40m
    • kupos.cl
      11h 15m
      0
      5:40 PM
      La Serena
      Bus Stop
      4:55 AM
      Antofagasta
      Terminal Buses Camus
      0
      kupos.cl
      Premium Economy
      $18
    Travel time is 0h 25m longer, but you will save $5

Cheapest bus trips Monday

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    8:00 AM
    Santiago, RM
    Terminal San Borja
    3:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $24
  • Turbus
    18h 25m
    0
    11:15 AM
    Santiago, RM
    Terminal Alameda
    5:40 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $32
  • Nueva Andimar Vip
    19h 0m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    2:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $33
  • Pluss Chile
    18h 20m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    2:05 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman San Andres
    18h 0m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $37

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Turbus
    18h 25m
    0
    11:15 AM
    Santiago, RM
    Terminal Alameda
    5:40 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $31
  • Cikbus Elité
    18h 15m
    0
    9:30 AM
    Santiago, RM
    Sur Bus Station
    3:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $31
  • Nueva Andimar Vip
    19h 0m
    0
    7:50 AM
    Santiago, RM
    Sur Bus Station
    2:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pluss Chile
    18h 20m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    2:05 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman Bus
    18h 50m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    5:50 AM
    Antofagasta
    Terminal Buses Camus
    0
    Pullman Bus
    First Class
    $37
  • Did you know that if you travel from Santiago, RM to Antofagasta via La Serena, you can save more than $5? You can find the corresponding connections below.
    • Recorrido CL
      18h 25m
      0
      10:30 AM
      Santiago, RM
      Sur Bus Station
      5:00 PM
      La Serena
      Bus Station
      0
      Recorrido CL
      Premium Economy
      $8
      • Waiting Time 0h 40m
    • kupos.cl
      11h 15m
      0
      5:40 PM
      La Serena
      Bus Stop
      4:55 AM
      Antofagasta
      Terminal Buses Camus
      0
      kupos.cl
      Premium Economy
      $18
    Travel time is 0h 10m longer, but you will save $5

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    8:00 AM
    Santiago, RM
    Terminal San Borja
    3:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $24
  • Pullman Bus
    18h 50m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    5:50 AM
    Antofagasta
    Terminal Buses Camus
    0
    Pullman Bus
    First Class
    $32
  • Nueva Andimar Vip
    19h 0m
    0
    7:50 AM
    Santiago, RM
    Sur Bus Station
    2:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman San Andres
    18h 30m
    0
    2:00 PM
    Santiago, RM
    Terminal San Borja
    8:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $37
  • Turbus
    17h 20m
    0
    1:30 AM
    Santiago, RM
    Terminal Alameda
    6:50 PM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    First Class
    $43

Cheapest bus trips Thursday

Prices are for one way and one person
  • Turbus
    18h 25m
    0
    11:45 PM
    Santiago, RM
    Terminal Alameda
    6:10 PM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $27
  • Cikbus Elité
    18h 45m
    0
    12:30 PM
    Santiago, RM
    Sur Bus Station
    7:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $31
  • Nueva Andimar Vip
    19h 0m
    0
    11:00 AM
    Santiago, RM
    Sur Bus Station
    6:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman San Andres
    18h 0m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cormar Bus
    18h 20m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:20 AM
    Antofagasta
    Terminal Buses Camus
    0
    Cormar Bus
    First Class
    $40

Cheapest bus trips Friday

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    8:00 AM
    Santiago, RM
    Terminal San Borja
    3:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $24
  • Turbus
    18h 15m
    0
    7:20 AM
    Santiago, RM
    Terminal Alameda
    1:35 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $27
  • Nueva Andimar Vip
    19h 0m
    0
    7:50 AM
    Santiago, RM
    Sur Bus Station
    2:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pluss Chile
    18h 20m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    2:05 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman Bus
    18h 50m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    5:50 AM
    Antofagasta
    Terminal Buses Camus
    0
    Pullman Bus
    First Class
    $37

Frequency of bus connections between Santiago, RM and Antofagasta

See here how frequent the connections between Santiago, RM and Antofagasta are, during different times and days of the week.
Friday is the busiest day, with more than 154 daily buses from Santiago, RM to Antofagasta. Tuesday has instead the fewest connections, with only 98 daily coaches between Santiago, RM and Antofagasta.
The busiest time of the day is the Afternoon, with 321 buses from Santiago, RM to Antofagasta, while Night sees the fewest connections between Santiago, RM and Antofagasta, with 7 offers.

Facts about the bus from Santiago, RM to Antofagasta

Compare all providers like Cikbus Elité, Pullman San Andres and Pluss Chile that travel 122 times every day by bus from Santiago, RM to Antofagasta in one click! Book your bus ticket from Santiago, RM to Antofagasta starting from $24!

Cheapest Bus $24
Fastest Bus 17h 0m
Earliest Bus 1:30 AM
Latest Bus 11:45 PM
Daily Bus Routes 122 Ø
Distance 677.0 miles
Bus Companies Cikbus Elité, Pullman San Andres, Pluss Chile, Turbus, Pullman Bus, Nueva Andimar Vip and Cormar Bus

Cheapest bus connections from Santiago, RM to Antofagasta

Every day, 122 buses from 7 bus companies leave Santiago, RM for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/26/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/20
Monday 04/21
Tuesday 04/22
Wednesday 04/23
Thursday 04/24
Friday 04/25
Saturday 04/26
$23
Sunday 04/27
$32
Monday 04/28
$32
Tuesday 04/29
$31
Wednesday 04/30
$31
Thursday 05/01
$23
Friday 05/02
$27
Saturday 05/03
$29
Sunday 05/04
$37
Monday 05/05
$27
Tuesday 05/06
$38
Wednesday 05/07
$27
Thursday 05/08
$23
Friday 05/09
$34
Saturday 05/10
$27
Sunday 05/11
$27
Monday 05/12
$23
Tuesday 05/13
$27
Wednesday 05/14
$23
Thursday 05/15
$44
Friday 05/16
$27
Saturday 05/17

The cheapest time to travel from Santiago, RM to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Antofagasta, for the next 30 days.
With a price starting from $24, Monday is the cheapest day for a bus from Santiago, RM to Antofagasta. Sunday instead is the most expensive day with prices starting from $31.
Morning is the cheapest day time for bus tickets from Santiago, RM to Antofagasta, with $24. Night is the most expensive time of the day with prices starting from $41.

How to save money travelling from Santiago, RM to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago, RM to Antofagasta are also emptier.

All bus stations and stops in Santiago, RM and Antofagasta

In the map below, you can see where to find all bus stations in Santiago, RM and Antofagasta.

Service and Comfort on the bus from Santiago, RM to Antofagasta

Want to know which seat classes are available on the buses from Santiago, RM to Antofagasta? Or which bus companies serve the route Santiago, RM to Antofagasta? Below you will find answers to your questions.

FAQs about the Santiago, RM to Antofagasta bus

How much does a Santiago, RM Antofagasta bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $24 and takes 19h 0m to reach Antofagasta. Compare offers to save money!

How much could I save by comparing buses from Santiago, RM to Antofagasta?

This route is offered by 7 companies with a range of ticket prices between $24 and $75. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Antofagasta.

On average, how many connections are available from Santiago, RM to Antofagasta each day?

Every day, the Santiago, RM to Antofagasta bus route is served by approximately 122 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago, RM to Antofagasta take?

The fastest bus from Santiago, RM to Antofagasta is offered by Turbus and takes 17h 0m. Bus tickets for this connection cost $32. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago, RM to Antofagasta?

The earliest bus arriving in Antofagasta from Santiago, RM starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago, RM to Antofagasta?

The latest bus trip departing from Santiago, RM for Antofagasta starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago, RM Antofagasta route?

When traveling by bus from Santiago, RM to Antofagasta, passengers can travel with Cikbus Elité, Pullman San Andres and Pluss Chile. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago, RM and Antofagasta?

You can check all the direct connections between Santiago, RM and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Cikbus Elité, Pullman San Andres and Pluss Chile.

What can I take with me on the Santiago, RM to Antofagasta bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago, RM Antofagasta bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Antofagasta on your planned travel date.

Available seat classes which are offered on the bus route Santiago, RM to Antofagasta

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to Antofagasta

Here’s an overview of the most popular bus routes to Santiago, RM and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Pucón, AR to Santiago, RM Buses from Pucón, AR to Santiago, RM
Buses Bariloche - Santiago, RM Buses Bariloche - Santiago, RM
La Serena to Santiago, RM bus La Serena to Santiago, RM bus
Buses to Santiago, RM from Puerto Montt Buses to Santiago, RM from Puerto Montt
Bus Calama to Antofagasta Bus Calama to Antofagasta
Buses Iquique to Antofagasta Buses Iquique to Antofagasta
From Arica, AP to Antofagasta bus From Arica, AP to Antofagasta bus
Bus Cochabamba to Antofagasta Bus Cochabamba to Antofagasta
Popular Airport Shuttles to Santiago, RM and to Antofagasta
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