Bus Tampa to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Tampa to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Tampa to Knoxville, TN from various bus operators like FlixBus for the next days.

today

tomorrow

Saturday

from $103

Sunday

Monday

from $91

Tuesday

Wednesday

Cheapest bus trips Saturday

Prices are for one way and one person

FlixBus

24h 15m

0

9:50 PM

Tampa
USF

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$103

A Bus from FlixBus goes from USF, Tampa (USA) at 5/10/2025 9:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/11/2025 10:05:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 24h 15m
FlixBus

23h 30m

0

10:35 PM

Tampa
Marion Street

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$103

A Bus from FlixBus goes from Marion Street, Tampa (USA) at 5/10/2025 10:35:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/11/2025 10:05:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 23h 30m
Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $11? You can find the corresponding connections below.
- FlixBus
  
  27h 45m
  
  0
  
  6:20 PM
  
  Tampa
  USF
  
  4:15 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $56
  
  A Bus from FlixBus goes from USF, Tampa (USA) at 5/11/2025 6:20:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 5/12/2025 4:15:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 9h 55m
- FlixBus
  
  4h 0m
  
  0
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  10:05 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 5/12/2025 6:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/12/2025 10:05:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 4h 0m
Travel time is 4h 15m longer, but you will save $11

Cheapest bus trips Monday

Prices are for one way and one person

FlixBus

24h 15m

0

9:50 PM

Tampa
USF

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$91

A Bus from FlixBus goes from USF, Tampa (USA) at 5/12/2025 9:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/13/2025 10:05:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 24h 15m
FlixBus

24h 40m

0

9:25 PM

Tampa
Marion Street

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$92

A Bus from FlixBus goes from Marion Street, Tampa (USA) at 5/12/2025 9:25:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/13/2025 10:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 24h 40m
Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $11? You can find the corresponding connections below.
- Busbud
  
  34h 55m
  
  0
  
  11:10 AM
  
  Tampa
  Marion Street
  
  11:45 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $50
  
  A Bus from Busbud goes from Marion Street, Tampa (USA) at 5/13/2025 11:10:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 5/13/2025 11:45:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 12h 35m
- FlixBus
  
  4h 0m
  
  0
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  10:05 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  0
  
  Economy
  
  $30
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 5/14/2025 6:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/14/2025 10:05:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 4h 0m
Travel time is 10h 40m longer, but you will save $11

Facts about the bus from Tampa to Knoxville, TN

Compare all providers like FlixBus that travel 2 times every day by bus from Tampa to Knoxville, TN in one click! Book your bus ticket from Tampa to Knoxville, TN starting from $91!

Cheapest Bus	$91
Fastest Bus	23h 30m
Earliest Bus	9:50 PM
Latest Bus	9:50 PM
Daily Bus Routes	2 Ø
Distance	560.1 miles
Bus Companies	FlixBus

Cheapest bus connections from Tampa to Knoxville, TN

Every day, 2 buses from 1 bus companies leave Tampa for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/08/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/04

Monday 05/05

Tuesday 05/06

Wednesday 05/07

Thursday 05/08

Friday 05/09

Saturday 05/10

$103

Sunday 05/11

Monday 05/12

$91

Tuesday 05/13

Wednesday 05/14

$77

Thursday 05/15

$99

Friday 05/16

$100

Saturday 05/17

Sunday 05/18

Monday 05/19

Tuesday 05/20

Wednesday 05/21

Thursday 05/22

Friday 05/23

Saturday 05/24

Sunday 05/25

Monday 05/26

Tuesday 05/27

Wednesday 05/28

Thursday 05/29

Friday 05/30

Saturday 05/31

How to save money travelling from Tampa to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to Knoxville, TN are also emptier.

All bus stations and stops in Tampa and Knoxville, TN

In the map below, you can see where to find all bus stations in Tampa and Knoxville, TN.

Marion Street

N Marion St 1211

USF

USF Holly Drive 3755

Greyhound Bus Station

East Polk Street 602

Western Union

Tampa Gateway Blvd, I 4 Exit 10 11706

Desoto Park

Greyhound Bus Station

E Magnolia Ave 100

Kingston Pike

Kingston Pike 6927

Transit Center

E Church Ave 301

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Service and Comfort on the bus from Tampa to Knoxville, TN

Want to know which seat classes are available on the buses from Tampa to Knoxville, TN? Or which bus companies serve the route Tampa to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Tampa to Knoxville, TN bus

How much does a Tampa Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $91 and takes 24h 15m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Tampa to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $91 and $103. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Tampa to Knoxville, TN each day?

Every day, the Tampa to Knoxville, TN bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to Knoxville, TN take?

The fastest bus from Tampa to Knoxville, TN is offered by FlixBus and takes 23h 30m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Tampa starts at 9:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to Knoxville, TN?

The latest bus trip departing from Tampa for Knoxville, TN starts at 9:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa Knoxville, TN route?

When traveling by bus from Tampa to Knoxville, TN, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and Knoxville, TN?

You can check all the direct connections between Tampa and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Tampa to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Tampa to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to Knoxville, TN

Here’s an overview of the most popular bus routes to Tampa and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!