Bus from Chicago to Knoxville, TN from $76

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Compare all timetables for the bus from Chicago to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Chicago to Knoxville, TN from various bus operators like Greyhound US or FlixBus for the next days.
today
from $97
tomorrow
from $96
Tuesday
from $76
Wednesday
from $82
Thursday
Friday
Saturday
from $103

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    16h 30m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $97
  • Greyhound US
    28h 30m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    6:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $98
  • FlixBus
    22h 50m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $99
  • Greyhound US
    21h 0m
    0
    10:10 PM
    Chicago
    Downtown Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $109

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    22h 55m
    0
    8:15 PM
    Chicago
    95th Red Line Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $96
  • FlixBus
    22h 50m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $112
  • Greyhound US
    21h 0m
    0
    10:10 PM
    Chicago
    Downtown Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $121
  • Greyhound US
    16h 30m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $135

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    22h 50m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $76
  • Greyhound US
    28h 30m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    6:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    22h 55m
    0
    8:15 PM
    Chicago
    95th Red Line Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    21h 0m
    0
    10:10 PM
    Chicago
    Downtown Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $96

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    22h 55m
    0
    8:15 PM
    Chicago
    95th Red Line Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $82
  • FlixBus
    22h 50m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $82
  • Greyhound US
    16h 30m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $104
  • Greyhound US
    21h 0m
    0
    10:10 PM
    Chicago
    Downtown Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $104

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    20h 40m
    0
    10:30 PM
    Chicago
    Downtown Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $103
  • Did you know that if you travel from Chicago to Knoxville, TN via Indianapolis, you can save more than $11? You can find the corresponding connections below.
    • Busbud
      30h 30m
      0
      12:40 PM
      Chicago
      Downtown Bus Station
      6:30 PM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $25
      • Waiting Time 14h 40m
    • FlixBus
      10h 0m
      0
      9:10 AM
      Indianapolis
      Central Bus Station
      7:10 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $67
    Travel time is 9h 50m longer, but you will save $11

Frequency of bus connections between Chicago and Knoxville, TN

See here how frequent the connections between Chicago and Knoxville, TN are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from Chicago to Knoxville, TN. Saturday has instead the fewest connections, with only 1 daily coaches between Chicago and Knoxville, TN.
The busiest time of the day is the Evening, with 17 buses from Chicago to Knoxville, TN, while Afternoon sees the fewest connections between Chicago and Knoxville, TN, with 2 offers.

Facts about the bus from Chicago to Knoxville, TN

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Chicago to Knoxville, TN in one click! Book your bus ticket from Chicago to Knoxville, TN starting from $76!

Cheapest Bus $76
Fastest Bus 16h 30m
Earliest Bus 6:10 AM
Latest Bus 10:30 PM
Daily Bus Routes 4 Ø
Distance 455.0 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Chicago to Knoxville, TN

Every day, 4 buses from 2 bus companies leave Chicago for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/11/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
$94
Monday 05/12
$94
Tuesday 05/13
$70
Wednesday 05/14
$104
Thursday 05/15
Friday 05/16
Saturday 05/17
$103
Sunday 05/18
$82
Monday 05/19
$97
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
Friday 05/23
$99
Saturday 05/24
$77
Sunday 05/25
$86
Monday 05/26
$90
Tuesday 05/27
Wednesday 05/28
Thursday 05/29
Friday 05/30
$80
Saturday 05/31
Sunday 06/01
$78
Monday 06/02
$73
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
$96
Saturday 06/07

The cheapest time to travel from Chicago to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Knoxville, TN, for the next 30 days.
With a price starting from $76, Tuesday is the cheapest day for a bus from Chicago to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $102.
Evening is the cheapest day time for bus tickets from Chicago to Knoxville, TN, with $76. Morning is the most expensive time of the day with prices starting from $97.

How to save money travelling from Chicago to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Knoxville, TN are also emptier.

All bus stations and stops in Chicago and Knoxville, TN

In the map below, you can see where to find all bus stations in Chicago and Knoxville, TN.

Service and Comfort on the bus from Chicago to Knoxville, TN

Want to know which seat classes are available on the buses from Chicago to Knoxville, TN? Or which bus companies serve the route Chicago to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Chicago to Knoxville, TN bus

How much does a Chicago Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $76 and takes 22h 50m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Chicago to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $76 and $181. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Chicago to Knoxville, TN each day?

Every day, the Chicago to Knoxville, TN bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Knoxville, TN take?

The fastest bus from Chicago to Knoxville, TN is offered by Greyhound US and takes 16h 30m. Bus tickets for this connection cost $97. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Chicago starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Knoxville, TN?

The latest bus trip departing from Chicago for Knoxville, TN starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Knoxville, TN route?

When traveling by bus from Chicago to Knoxville, TN, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Knoxville, TN?

You can check all the direct connections between Chicago and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Chicago to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Knoxville, TN

Here’s an overview of the most popular bus routes to Chicago and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Chicago and to Knoxville, TN
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