Bus from Orlando, FL to Knoxville, TN from $89

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Compare all timetables for the bus from Orlando, FL to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Orlando, FL to Knoxville, TN from various bus operators like FlixBus or Greyhound US for the next days.
today
tomorrow
Tuesday
Wednesday
from $91
Thursday
from $93
Friday
from $89
Saturday
from $95

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    24h 0m
    0
    10:40 PM
    Orlando, FL
    Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $91
  • Greyhound US
    16h 50m
    0
    5:15 AM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $100
  • FlixBus
    32h 30m
    0
    2:10 PM
    Orlando, FL
    Florida Mall
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $116
  • Did you know that if you travel from Orlando, FL to Knoxville, TN via Atlanta, GA, you can save more than $17? You can find the corresponding connections below.
    • Busbud
      23h 25m
      0
      10:40 PM
      Orlando, FL
      Bus Station
      7:15 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $44
      • Waiting Time 10h 50m
    • FlixBus
      4h 0m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      10:05 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $30
    Travel time is 6h 35m longer, but you will save $17

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    24h 0m
    0
    10:40 PM
    Orlando, FL
    Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $93
  • FlixBus
    16h 5m
    0
    6:00 AM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $94
  • FlixBus
    30h 25m
    0
    3:40 PM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $94
  • Did you know that if you travel from Orlando, FL to Knoxville, TN via Atlanta, GA, you can save more than $19? You can find the corresponding connections below.
    • Busbud
      23h 25m
      0
      10:40 PM
      Orlando, FL
      Bus Station
      7:15 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $44
      • Waiting Time 10h 50m
    • FlixBus
      4h 0m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      10:05 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $30
    Travel time is 7h 20m longer, but you will save $19

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    16h 50m
    0
    5:15 AM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $89
  • FlixBus
    24h 0m
    0
    10:40 PM
    Orlando, FL
    Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $91
  • FlixBus
    32h 30m
    0
    2:10 PM
    Orlando, FL
    Florida Mall
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $91
  • FlixBus
    30h 25m
    0
    3:40 PM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $95
  • Did you know that if you travel from Orlando, FL to Knoxville, TN via Atlanta, GA, you can save more than $15? You can find the corresponding connections below.
    • Busbud
      23h 25m
      0
      10:40 PM
      Orlando, FL
      Bus Station
      7:15 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $44
      • Waiting Time 10h 50m
    • FlixBus
      4h 0m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      10:05 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $30
    Travel time is 6h 35m longer, but you will save $15

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    16h 5m
    0
    6:00 AM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $95
  • FlixBus
    30h 25m
    0
    3:40 PM
    Orlando, FL
    Bus Station
    10:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $103
  • Did you know that if you travel from Orlando, FL to Knoxville, TN via Atlanta, GA, you can save more than $21? You can find the corresponding connections below.
    • Busbud
      23h 25m
      0
      10:40 PM
      Orlando, FL
      Bus Station
      7:15 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $44
      • Waiting Time 10h 50m
    • FlixBus
      4h 0m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      10:05 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $30
    Travel time is 7h 20m longer, but you will save $21

Frequency of bus connections between Orlando, FL and Knoxville, TN

See here how frequent the connections between Orlando, FL and Knoxville, TN are, during different times and days of the week.
Friday is the busiest day, with more than 4 daily buses from Orlando, FL to Knoxville, TN. Saturday has instead the fewest connections, with only 2 daily coaches between Orlando, FL and Knoxville, TN.
The busiest time of the day is the Afternoon, with 5 buses from Orlando, FL to Knoxville, TN, while Morning sees the fewest connections between Orlando, FL and Knoxville, TN, with 2 offers.

Facts about the bus from Orlando, FL to Knoxville, TN

Compare all providers like FlixBus and Greyhound US that travel 3 times every day by bus from Orlando, FL to Knoxville, TN in one click! Book your bus ticket from Orlando, FL to Knoxville, TN starting from $89!

Cheapest Bus $89
Fastest Bus 16h 5m
Earliest Bus 5:15 AM
Latest Bus 3:40 PM
Daily Bus Routes 3 Ø
Distance 534.0 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Orlando, FL to Knoxville, TN

Every day, 3 buses from 2 bus companies leave Orlando, FL for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/11/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
$91
Monday 05/12
Tuesday 05/13
Wednesday 05/14
$91
Thursday 05/15
$93
Friday 05/16
$92
Saturday 05/17
$95
Sunday 05/18
Monday 05/19
$121
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
Friday 05/23
Saturday 05/24
$82
Sunday 05/25
$80
Monday 05/26
Tuesday 05/27
Wednesday 05/28
Thursday 05/29
Friday 05/30
Saturday 05/31
Sunday 06/01
$84
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07

The cheapest time to travel from Orlando, FL to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Orlando, FL to Knoxville, TN, for the next 30 days.
With a price starting from $89, Friday is the cheapest day for a bus from Orlando, FL to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $95.
Night is the cheapest day time for bus tickets from Orlando, FL to Knoxville, TN, with $89. Morning is the most expensive time of the day with prices starting from $94.

How to save money travelling from Orlando, FL to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Orlando, FL to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Orlando, FL to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Orlando, FL to Knoxville, TN are also emptier.

All bus stations and stops in Orlando, FL and Knoxville, TN

In the map below, you can see where to find all bus stations in Orlando, FL and Knoxville, TN.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Orlando, FL to Knoxville, TN? Compare all modes of transports from Orlando, FL to Knoxville, TN.

Service and Comfort on the bus from Orlando, FL to Knoxville, TN

Want to know which seat classes are available on the buses from Orlando, FL to Knoxville, TN? Or which bus companies serve the route Orlando, FL to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Orlando, FL to Knoxville, TN bus

How much does a Orlando, FL Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $89 and takes 16h 50m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Orlando, FL to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $89 and $116. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Orlando, FL to Knoxville, TN each day?

Every day, the Orlando, FL to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Orlando, FL to Knoxville, TN take?

The fastest bus from Orlando, FL to Knoxville, TN is offered by FlixBus and takes 16h 5m. Bus tickets for this connection cost $94. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Orlando, FL to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Orlando, FL starts at 5:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Orlando, FL to Knoxville, TN?

The latest bus trip departing from Orlando, FL for Knoxville, TN starts at 3:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Orlando, FL Knoxville, TN route?

When traveling by bus from Orlando, FL to Knoxville, TN, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Orlando, FL and Knoxville, TN?

You can check all the direct connections between Orlando, FL and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Orlando, FL to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Orlando, FL Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Orlando, FL Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Orlando, FL to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Orlando, FL to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Orlando, FL and to Knoxville, TN

Here’s an overview of the most popular bus routes to Orlando, FL and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Orlando, FL and to Knoxville, TN
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