Bus from Detroit to Knoxville, TN from $74

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Compare all timetables for the bus from Detroit to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Detroit to Knoxville, TN from various bus operators like Greyhound US for the next days.
today
tomorrow
Tuesday
Wednesday
Thursday
from $74
Friday
from $76
Saturday
from $83

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    12h 30m
    0
    6:40 AM
    Detroit
    Central Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $74
  • Greyhound US
    23h 15m
    0
    11:25 PM
    Detroit
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    22h 25m
    0
    8:15 PM
    Detroit
    Central Bus Station
    6:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $88
  • Greyhound US
    21h 5m
    0
    10:05 PM
    Detroit
    Central Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $88

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    12h 30m
    0
    6:40 AM
    Detroit
    Central Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    21h 5m
    0
    10:05 PM
    Detroit
    Central Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $88
  • Greyhound US
    22h 25m
    0
    8:15 PM
    Detroit
    Central Bus Station
    6:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $90
  • Greyhound US
    23h 15m
    0
    11:25 PM
    Detroit
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $90

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    12h 30m
    0
    6:40 AM
    Detroit
    Central Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $83
  • Greyhound US
    21h 50m
    0
    8:15 PM
    Detroit
    Central Bus Station
    6:05 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    23h 0m
    0
    11:25 PM
    Detroit
    Central Bus Station
    10:25 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    21h 5m
    0
    10:05 PM
    Detroit
    Central Bus Station
    7:10 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $88

Frequency of bus connections between Detroit and Knoxville, TN

See here how frequent the connections between Detroit and Knoxville, TN are, during different times and days of the week.
Thursday is the busiest day, with more than 4 daily buses from Detroit to Knoxville, TN. Thursday has instead the fewest connections, with only 4 daily coaches between Detroit and Knoxville, TN.
The busiest time of the day is the Evening, with 9 buses from Detroit to Knoxville, TN, while Morning sees the fewest connections between Detroit and Knoxville, TN, with 3 offers.

Facts about the bus from Detroit to Knoxville, TN

Compare all providers like Greyhound US that travel 4 times every day by bus from Detroit to Knoxville, TN in one click! Book your bus ticket from Detroit to Knoxville, TN starting from $74!

Cheapest Bus $74
Fastest Bus 12h 30m
Earliest Bus 6:40 AM
Latest Bus 11:25 PM
Daily Bus Routes 4 Ø
Distance 442.5 miles
Bus Companies Greyhound US

Cheapest bus connections from Detroit to Knoxville, TN

Every day, 4 buses from 1 bus companies leave Detroit for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/11/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
$74
Friday 05/16
$72
Saturday 05/17
$83
Sunday 05/18
$72
Monday 05/19
$81
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
$76
Friday 05/23
Saturday 05/24
Sunday 05/25
Monday 05/26
Tuesday 05/27
Wednesday 05/28
Thursday 05/29
$67
Friday 05/30
Saturday 05/31
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07

The cheapest time to travel from Detroit to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Detroit to Knoxville, TN, for the next 30 days.
With a price starting from $74, Thursday is the cheapest day for a bus from Detroit to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $83.
Morning is the cheapest day time for bus tickets from Detroit to Knoxville, TN, with $74. Evening is the most expensive time of the day with prices starting from $87.

How to save money travelling from Detroit to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Detroit to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Detroit to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Detroit to Knoxville, TN are also emptier.

Beloved bus companies from Detroit to Knoxville, TN

These are the most booked bus companies between Detroit to Knoxville, TN from our users.

Greyhound US from Detroit to Knoxville, TN

Greyhound US

Here you will find the key facts about the Greyhound US bus route Detroit to Knoxville, TN:

Cheapest Price $74
Fastest Bus 12h 30m
Earliest Bus 6:40 AM
Last Bus 11:25 PM
Daily Connections 4 Ø
Found on 5/9/2025

All bus stations and stops in Detroit and Knoxville, TN

In the map below, you can see where to find all bus stations in Detroit and Knoxville, TN.

Service and Comfort on the bus from Detroit to Knoxville, TN

Want to know which seat classes are available on the buses from Detroit to Knoxville, TN? Or which bus companies serve the route Detroit to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Detroit to Knoxville, TN bus

How much does a Detroit Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 12h 30m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Detroit to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $74 and $90. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Detroit to Knoxville, TN each day?

Every day, the Detroit to Knoxville, TN bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Detroit to Knoxville, TN take?

The fastest bus from Detroit to Knoxville, TN is offered by Greyhound US and takes 12h 30m. Bus tickets for this connection cost $74. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Detroit to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Detroit starts at 6:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Detroit to Knoxville, TN?

The latest bus trip departing from Detroit for Knoxville, TN starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Detroit Knoxville, TN route?

When traveling by bus from Detroit to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Detroit and Knoxville, TN?

You can check all the direct connections between Detroit and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Detroit to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Detroit Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Detroit Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Detroit to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Detroit to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Detroit and to Knoxville, TN

Here’s an overview of the most popular bus routes to Detroit and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Detroit from New York Buses to Detroit from New York
Bus to Detroit from Windsor, ON Bus to Detroit from Windsor, ON
Bus London, ON to Detroit Bus London, ON to Detroit
Bus Grand Rapids, MI - Detroit Bus Grand Rapids, MI - Detroit
Buses Indianapolis to Knoxville, TN Buses Indianapolis to Knoxville, TN
Buses from Cincinnati to Knoxville, TN Buses from Cincinnati to Knoxville, TN
Bus Tampa - Knoxville, TN Bus Tampa - Knoxville, TN
Bus Orlando, FL - Knoxville, TN Bus Orlando, FL - Knoxville, TN
Popular Airport Shuttles to Detroit and to Knoxville, TN
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