Bus Houston to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Houston to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Houston to Knoxville, TN from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today

from $123

tomorrow

Monday

Tuesday

Wednesday

Thursday

from $117

Friday

Cheapest bus trips today

Prices are for one way and one person

FlixBus

32h 20m

0

1:45 PM

Houston
Main St & Airline Dr

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$123

A Bus from FlixBus goes from Main St & Airline Dr, Houston (USA) at 5/10/2025 1:45:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/11/2025 10:05:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 32h 20m
FlixBus

29h 5m

0

5:00 PM

Houston
Downtown Houston

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$123

A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/10/2025 5:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/11/2025 10:05:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 29h 5m
Greyhound US

24h 5m

0

10:00 PM

Houston
Harrisburg Blvd Station

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$123

A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/10/2025 10:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/11/2025 10:05:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 24h 5m
Greyhound Lines Mexico

36h 35m

0

10:05 AM

Houston
SW Agencia Autobuses

10:40 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$126

A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 5/10/2025 10:05:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/11/2025 10:40:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 36h 35m

Cheapest bus trips Thursday

Prices are for one way and one person

FlixBus

32h 5m

0

2:00 PM

Houston
Uptown/Upper Kirby

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$117

A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/15/2025 2:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/16/2025 10:05:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 32h 5m
FlixBus

29h 5m

0

5:00 PM

Houston
Downtown Houston

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$118

A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/15/2025 5:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/16/2025 10:05:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 29h 5m
Greyhound US

24h 5m

0

10:00 PM

Houston
Harrisburg Blvd Station

10:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$141

A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/15/2025 10:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/16/2025 10:05:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 24h 5m
Greyhound Lines Mexico

36h 35m

0

10:05 AM

Houston
SW Agencia Autobuses

10:40 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$143

A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 5/15/2025 10:05:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/16/2025 10:40:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 36h 35m

Frequency of bus connections between Houston and Knoxville, TN

See here how frequent the connections between Houston and Knoxville, TN are, during different times and days of the week.

Saturday is the busiest day, with more than 8 daily buses from Houston to Knoxville, TN. Thursday has instead the fewest connections, with only 6 daily coaches between Houston and Knoxville, TN.

The busiest time of the day is the Afternoon, with 7 buses from Houston to Knoxville, TN, while Evening sees the fewest connections between Houston and Knoxville, TN, with 3 offers.

Facts about the bus from Houston to Knoxville, TN

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 7 times every day by bus from Houston to Knoxville, TN in one click! Book your bus ticket from Houston to Knoxville, TN starting from $117!

Cheapest Bus	$117
Fastest Bus	24h 5m
Earliest Bus	6:35 AM
Latest Bus	10:00 PM
Daily Bus Routes	7 Ø
Distance	791.0 miles
Bus Companies	FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest bus connections from Houston to Knoxville, TN

Every day, 7 buses from 3 bus companies leave Houston for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/11/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/04

Monday 05/05

Tuesday 05/06

Wednesday 05/07

Thursday 05/08

Friday 05/09

Saturday 05/10

$123

Sunday 05/11

Monday 05/12

Tuesday 05/13

$109

Wednesday 05/14

$115

Thursday 05/15

$117

Friday 05/16

$112

Saturday 05/17

Sunday 05/18

$103

Monday 05/19

Tuesday 05/20

Wednesday 05/21

Thursday 05/22

Friday 05/23

Saturday 05/24

$117

Sunday 05/25

Monday 05/26

Tuesday 05/27

Wednesday 05/28

$121

Thursday 05/29

Friday 05/30

$116

Saturday 05/31

The cheapest time to travel from Houston to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Knoxville, TN, for the next 30 days.

With a price starting from $117, Thursday is the cheapest day for a bus from Houston to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $123.

Afternoon is the cheapest day time for bus tickets from Houston to Knoxville, TN, with $117. Morning is the most expensive time of the day with prices starting from $125.

How to save money travelling from Houston to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Knoxville, TN are also emptier.

All bus stations and stops in Houston and Knoxville, TN

In the map below, you can see where to find all bus stations in Houston and Knoxville, TN.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

SW Agencia Autobuses

Southwest Fwy 6590

Greyhound Bus Station

E Magnolia Ave 100

Kingston Pike

Kingston Pike 6927

Transit Center

E Church Ave 301

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Service and Comfort on the bus from Houston to Knoxville, TN

Want to know which seat classes are available on the buses from Houston to Knoxville, TN? Or which bus companies serve the route Houston to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Houston to Knoxville, TN bus

How much does a Houston Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $117 and takes 32h 5m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Houston to Knoxville, TN?

This route is offered by 3 companies with a range of ticket prices between $117 and $144. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Houston to Knoxville, TN each day?

Every day, the Houston to Knoxville, TN bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Knoxville, TN take?

The fastest bus from Houston to Knoxville, TN is offered by Greyhound US and takes 24h 5m. Bus tickets for this connection cost $123. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Houston starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Knoxville, TN?

The latest bus trip departing from Houston for Knoxville, TN starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Knoxville, TN route?

When traveling by bus from Houston to Knoxville, TN, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Knoxville, TN?

You can check all the direct connections between Houston and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the Houston to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Houston to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Knoxville, TN

Here’s an overview of the most popular bus routes to Houston and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!