Bus from Durham, NC to Greenville, SC from $35

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Compare all timetables for the bus from Durham, NC to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Durham, NC to Greenville, SC from various bus operators like FlixBus, Wanda Coach or Greyhound US for the next days.
today
from $36
tomorrow
Saturday
from $50
Sunday
from $41
Monday
from $35
Tuesday
from $38
Wednesday
from $38

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    4h 25m
    0
    3:55 AM
    Durham, NC
    Transportation Center
    8:20 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $36
  • FlixBus
    4h 50m
    0
    5:55 AM
    Durham, NC
    Transportation Center
    10:45 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $36
  • Greyhound US
    6h 0m
    0
    4:55 AM
    Durham, NC
    Transportation Center
    10:55 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $36
  • Wanda Coach
    4h 40m
    0
    1:30 AM
    Durham, NC
    BP Guess Road
    6:10 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50
  • Wanda Coach
    4h 40m
    0
    4:20 AM
    Durham, NC
    BP Guess Road
    9:00 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50

Cheapest bus trips Saturday

Prices are for one way and one person
  • Wanda Coach
    4h 40m
    0
    1:30 AM
    Durham, NC
    BP Hillandale Rd
    6:10 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50
  • Wanda Coach
    4h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    9:00 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50
  • Wanda Coach
    4h 40m
    0
    1:30 AM
    Durham, NC
    BP Guess Road
    6:10 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50
  • Wanda Coach
    4h 40m
    0
    4:20 AM
    Durham, NC
    BP Guess Road
    9:00 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    6h 0m
    0
    4:55 AM
    Durham, NC
    Exxon
    10:55 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $41
  • FlixBus
    4h 25m
    0
    3:55 AM
    Durham, NC
    Exxon
    8:20 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $43
  • FlixBus
    4h 50m
    0
    5:55 AM
    Durham, NC
    Exxon
    10:45 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $43
  • Wanda Coach
    4h 40m
    0
    1:30 AM
    Durham, NC
    BP Hillandale Rd
    6:10 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50
  • Wanda Coach
    4h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    9:00 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    4h 25m
    0
    3:55 AM
    Durham, NC
    Transportation Center
    8:20 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $35
  • Greyhound US
    6h 0m
    0
    4:55 AM
    Durham, NC
    Transportation Center
    10:55 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $35
  • FlixBus
    4h 50m
    0
    5:55 AM
    Durham, NC
    Transportation Center
    10:45 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $36
  • FlixBus
    4h 35m
    0
    8:15 AM
    Durham, NC
    Transportation Center
    12:50 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $39
  • Greyhound US
    8h 5m
    0
    9:35 AM
    Durham, NC
    Transportation Center
    5:40 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $52

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    4h 25m
    0
    3:55 AM
    Durham, NC
    Exxon
    8:20 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $38
  • Greyhound US
    6h 0m
    0
    4:55 AM
    Durham, NC
    Exxon
    10:55 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $38
  • FlixBus
    4h 50m
    0
    5:55 AM
    Durham, NC
    Exxon
    10:45 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $39
  • FlixBus
    4h 35m
    0
    8:15 AM
    Durham, NC
    Exxon
    12:50 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $41

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    4h 25m
    0
    3:55 AM
    Durham, NC
    Exxon
    8:20 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $38
  • FlixBus
    4h 50m
    0
    5:55 AM
    Durham, NC
    Exxon
    10:45 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $40
  • Greyhound US
    6h 0m
    0
    4:55 AM
    Durham, NC
    Exxon
    10:55 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $48
  • Wanda Coach
    4h 40m
    0
    1:30 AM
    Durham, NC
    BP Hillandale Rd
    6:10 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50
  • Wanda Coach
    4h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    9:00 AM
    Greenville, SC
    McDonald's
    0
    Wanda Coach
    Economy
    $50

Frequency of bus connections between Durham, NC and Greenville, SC

See here how frequent the connections between Durham, NC and Greenville, SC are, during different times and days of the week.
Sunday is the busiest day, with more than 7 daily buses from Durham, NC to Greenville, SC. Saturday has instead the fewest connections, with only 4 daily coaches between Durham, NC and Greenville, SC.
The busiest time of the day is the Night, with 25 buses from Durham, NC to Greenville, SC, while Afternoon sees the fewest connections between Durham, NC and Greenville, SC, with 3 offers.

Facts about the bus from Durham, NC to Greenville, SC

Compare all providers like FlixBus, Wanda Coach and Greyhound US that travel 5 times every day by bus from Durham, NC to Greenville, SC in one click! Book your bus ticket from Durham, NC to Greenville, SC starting from $35!

Cheapest Bus $35
Fastest Bus 4h 25m
Earliest Bus 1:30 AM
Latest Bus 8:15 AM
Daily Bus Routes 5 Ø
Distance 211.7 miles
Bus Companies FlixBus, Wanda Coach and Greyhound US

Cheapest bus connections from Durham, NC to Greenville, SC

Every day, 5 buses from 3 bus companies leave Durham, NC for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/11/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/06
Monday 04/07
Tuesday 04/08
Wednesday 04/09
Thursday 04/10
$50
Friday 04/11
Saturday 04/12
$50
Sunday 04/13
$41
Monday 04/14
$35
Tuesday 04/15
$38
Wednesday 04/16
$38
Thursday 04/17
Friday 04/18
$50
Saturday 04/19
$50
Sunday 04/20
Monday 04/21
Tuesday 04/22
Wednesday 04/23
Thursday 04/24
Friday 04/25
Saturday 04/26
Sunday 04/27
Monday 04/28
Tuesday 04/29
Wednesday 04/30
Thursday 05/01
Friday 05/02
Saturday 05/03

The cheapest time to travel from Durham, NC to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Durham, NC to Greenville, SC, for the next 30 days.
With a price starting from $35, Monday is the cheapest day for a bus from Durham, NC to Greenville, SC. Saturday instead is the most expensive day with prices starting from $50.
Night is the cheapest day time for bus tickets from Durham, NC to Greenville, SC, with $35. Morning is the most expensive time of the day with prices starting from $39.

How to save money travelling from Durham, NC to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Durham, NC to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Durham, NC to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Durham, NC to Greenville, SC are also emptier.

Beloved bus companies from Durham, NC to Greenville, SC

These are the most booked bus companies between Durham, NC to Greenville, SC from our users.

Wanda Coach from Durham, NC to Greenville, SC

Wanda Coach

Here you will find the key facts about the Wanda Coach bus route Durham, NC to Greenville, SC:

Cheapest Price $50
Fastest Bus 4h 40m
Earliest Bus 1:30 AM
Last Bus 4:20 AM
Daily Connections 2 Ø
Found on 4/8/2025

All bus stations and stops in Durham, NC and Greenville, SC

In the map below, you can see where to find all bus stations in Durham, NC and Greenville, SC.

Service and Comfort on the bus from Durham, NC to Greenville, SC

Want to know which seat classes are available on the buses from Durham, NC to Greenville, SC? Or which bus companies serve the route Durham, NC to Greenville, SC? Below you will find answers to your questions.

FAQs about the Durham, NC to Greenville, SC bus

How much does a Durham, NC Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $35 and takes 4h 25m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Durham, NC to Greenville, SC?

This route is offered by 3 companies with a range of ticket prices between $35 and $52. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Durham, NC to Greenville, SC each day?

Every day, the Durham, NC to Greenville, SC bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Durham, NC to Greenville, SC take?

The fastest bus from Durham, NC to Greenville, SC is offered by FlixBus and takes 4h 25m. Bus tickets for this connection cost $36. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Durham, NC to Greenville, SC?

The earliest bus arriving in Greenville, SC from Durham, NC starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Durham, NC to Greenville, SC?

The latest bus trip departing from Durham, NC for Greenville, SC starts at 8:15 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Durham, NC Greenville, SC route?

When traveling by bus from Durham, NC to Greenville, SC, passengers can travel with FlixBus, Wanda Coach and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Durham, NC and Greenville, SC?

You can check all the direct connections between Durham, NC and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Wanda Coach and Greyhound US.

What can I take with me on the Durham, NC to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Durham, NC Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Durham, NC Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Durham, NC to Greenville, SC on your planned travel date.

Available seat classes which are offered on the bus route Durham, NC to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Durham, NC and to Greenville, SC

Here’s an overview of the most popular bus routes to Durham, NC and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Durham, NC and to Greenville, SC
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