Bus San Antonio, TX to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from San Antonio, TX to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Greenville, SC from various bus operators like Greyhound US, FlixBus or Greyhound Lines Mexico for the next days.

today

tomorrow

Sunday

from $151

Monday

from $127

Tuesday

Wednesday

from $120

Thursday

from $122

Cheapest bus trips Sunday

Prices are for one way and one person

Greyhound Lines Mexico

36h 35m

0

7:00 PM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$151

A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 4/13/2025 7:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/15/2025 7:35:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 36h 35m
Greyhound US

30h 55m

0

1:30 PM

San Antonio, TX
Bus Station

8:25 PM

Greenville, SC
Woodruff Rd

0

Economy

$156

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/13/2025 1:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/14/2025 8:25:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 30h 55m
FlixBus

24h 40m

0

10:00 AM

San Antonio, TX
Bus Station

10:40 AM

Greenville, SC
Woodruff Rd

0

Economy

$162

A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 4/13/2025 10:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/14/2025 10:40:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 24h 40m
Greyhound US

30h 30m

0

1:05 AM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$217

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/13/2025 1:05:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/14/2025 7:35:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 30h 30m
Did you know that if you travel from San Antonio, TX to Greenville, SC via Austin, you can save more than $28? You can find the corresponding connections below.
- Busbud
  
  28h 35m
  
  0
  
  6:05 AM
  
  San Antonio, TX
  Bus Station
  
  7:40 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  0
  
  Economy
  
  $16
  
  A Bus from Busbud goes from Bus Station, San Antonio, TX (USA) at 4/14/2025 6:05:00 AM to 5119 Eastside Bus Plaza, Austin (USA) arriving at 4/14/2025 7:40:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 1h 35m
- Busbud
  
  25h 40m
  
  0
  
  9:00 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  10:40 AM
  
  Greenville, SC
  Woodruff Rd
  
  0
  
  Economy
  
  $107
  
  A Bus from Busbud goes from 5119 Eastside Bus Plaza, Austin (USA) at 4/14/2025 9:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/15/2025 10:40:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 40m
Travel time is 3h 55m longer, but you will save $28

Cheapest bus trips Monday

Prices are for one way and one person

Greyhound US

30h 55m

0

1:30 PM

San Antonio, TX
Bus Station

8:25 PM

Greenville, SC
Woodruff Rd

0

Economy

$127

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/14/2025 1:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/15/2025 8:25:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 30h 55m
Greyhound Lines Mexico

36h 35m

0

7:00 PM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$127

A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 4/14/2025 7:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/16/2025 7:35:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 36h 35m
FlixBus

24h 40m

0

10:00 AM

San Antonio, TX
Bus Station

10:40 AM

Greenville, SC
Woodruff Rd

0

Economy

$128

A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 4/14/2025 10:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/15/2025 10:40:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 24h 40m
Greyhound US

30h 30m

0

1:05 AM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$151

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/14/2025 1:05:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/15/2025 7:35:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 30h 30m

Cheapest bus trips Wednesday

Prices are for one way and one person

Greyhound US

30h 55m

0

1:30 PM

San Antonio, TX
Bus Station

8:25 PM

Greenville, SC
Woodruff Rd

0

Economy

$120

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/16/2025 1:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/17/2025 8:25:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 30h 55m
FlixBus

47h 50m

0

7:45 AM

San Antonio, TX
Pearl District

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$121

A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 4/16/2025 7:45:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/18/2025 7:35:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 47h 50m
Greyhound Lines Mexico

36h 35m

0

7:00 PM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$122

A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 4/16/2025 7:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/18/2025 7:35:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 36h 35m
Greyhound US

30h 30m

0

1:05 AM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$124

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/16/2025 1:05:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/17/2025 7:35:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 30h 30m

Cheapest bus trips Thursday

Prices are for one way and one person

Greyhound US

30h 30m

0

1:05 AM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$122

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/17/2025 1:05:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/18/2025 7:35:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 30h 30m
Greyhound Lines Mexico

36h 35m

0

7:00 PM

San Antonio, TX
Bus Station

7:35 AM

Greenville, SC
Woodruff Rd

0

Economy

$122

A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 4/17/2025 7:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/19/2025 7:35:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 36h 35m
Greyhound US

30h 55m

0

1:30 PM

San Antonio, TX
Bus Station

8:25 PM

Greenville, SC
Woodruff Rd

0

Economy

$138

A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 4/17/2025 1:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/18/2025 8:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 30h 55m
FlixBus

24h 40m

0

10:00 AM

San Antonio, TX
Bus Station

10:40 AM

Greenville, SC
Woodruff Rd

0

Economy

$179

A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 4/17/2025 10:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/18/2025 10:40:00 AM. 50 Economy ticket for $179 per person are available. Travel duration is 24h 40m

Frequency of bus connections between San Antonio, TX and Greenville, SC

See here how frequent the connections between San Antonio, TX and Greenville, SC are, during different times and days of the week.

Wednesday is the busiest day, with more than 5 daily buses from San Antonio, TX to Greenville, SC. Sunday has instead the fewest connections, with only 4 daily coaches between San Antonio, TX and Greenville, SC.

The busiest time of the day is the Morning, with 5 buses from San Antonio, TX to Greenville, SC, while Afternoon sees the fewest connections between San Antonio, TX and Greenville, SC, with 4 offers.

Facts about the bus from San Antonio, TX to Greenville, SC

Compare all providers like Greyhound US, FlixBus and Greyhound Lines Mexico that travel 4 times every day by bus from San Antonio, TX to Greenville, SC in one click! Book your bus ticket from San Antonio, TX to Greenville, SC starting from $120!

Cheapest Bus	$120
Fastest Bus	24h 40m
Earliest Bus	1:05 AM
Latest Bus	7:00 PM
Daily Bus Routes	4 Ø
Distance	1,012.1 miles
Bus Companies	Greyhound US, FlixBus and Greyhound Lines Mexico

Cheapest bus connections from San Antonio, TX to Greenville, SC

Every day, 4 buses from 3 bus companies leave San Antonio, TX for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/11/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/06

Monday 04/07

Tuesday 04/08

Wednesday 04/09

Thursday 04/10

Friday 04/11

Saturday 04/12

Sunday 04/13

$151

Monday 04/14

$127

Tuesday 04/15

Wednesday 04/16

$120

Thursday 04/17

$122

Friday 04/18

Saturday 04/19

$141

Sunday 04/20

Monday 04/21

Tuesday 04/22

Wednesday 04/23

Thursday 04/24

Friday 04/25

Saturday 04/26

Sunday 04/27

Monday 04/28

Tuesday 04/29

Wednesday 04/30

Thursday 05/01

Friday 05/02

Saturday 05/03

The cheapest time to travel from San Antonio, TX to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Greenville, SC, for the next 30 days.

With a price starting from $120, Wednesday is the cheapest day for a bus from San Antonio, TX to Greenville, SC. Sunday instead is the most expensive day with prices starting from $151.

Afternoon is the cheapest day time for bus tickets from San Antonio, TX to Greenville, SC, with $120. Night is the most expensive time of the day with prices starting from $122.

How to save money travelling from San Antonio, TX to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Greenville, SC are also emptier.

All bus stations and stops in San Antonio, TX and Greenville, SC

In the map below, you can see where to find all bus stations in San Antonio, TX and Greenville, SC.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Central Station

Urban Loop

McDonald's

Woodruff Rd 1111

Greyhound Bus Station

Hendrix Dr 9

Woodruff Rd

Woodruff Rd 1116

Guadalajara Supermarket

White Horse Rd 2803

N Church St

Service and Comfort on the bus from San Antonio, TX to Greenville, SC

Want to know which seat classes are available on the buses from San Antonio, TX to Greenville, SC? Or which bus companies serve the route San Antonio, TX to Greenville, SC? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Greenville, SC bus

How much does a San Antonio, TX Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $120 and takes 30h 55m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Greenville, SC?

This route is offered by 3 companies with a range of ticket prices between $120 and $217. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from San Antonio, TX to Greenville, SC each day?

Every day, the San Antonio, TX to Greenville, SC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Greenville, SC take?

The fastest bus from San Antonio, TX to Greenville, SC is offered by FlixBus and takes 24h 40m. Bus tickets for this connection cost $162. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Greenville, SC?

The earliest bus arriving in Greenville, SC from San Antonio, TX starts at 1:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Greenville, SC?

The latest bus trip departing from San Antonio, TX for Greenville, SC starts at 7:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Greenville, SC route?

When traveling by bus from San Antonio, TX to Greenville, SC, passengers can travel with Greyhound US, FlixBus and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Greenville, SC?

You can check all the direct connections between San Antonio, TX and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Greenville, SC on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Greenville, SC

Here’s an overview of the most popular bus routes to San Antonio, TX and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!